Results 1 to 10 of about 521,206 (335)

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

open access: yesNucleic Acids Res., 2021
The PRoteomics IDEntifications (PRIDE) database (https://www.ebi.ac.uk/pride/) is the world's largest data repository of mass spectrometry-based proteomics data.
Yasset Pérez-Riverol   +13 more
semanticscholar   +1 more source

Biomarkers of Endometriosis

open access: yesFertility & Reproduction, 2022
Background: Endometriosis is an under-recognised and often misdiagnosed chronic disease that affects one in ten women. It occurs when cells similar to those that line a uterus grow in other parts of the body, usually around the pelvis.
Kerryn L. GARRETT   +11 more
doaj   +1 more source

Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

open access: yesClinical Proteomics, 2023
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various disciplines of laboratory medicine to identify and quantify biomolecules in a variety of biological specimens.
A. Birhanu
semanticscholar   +1 more source

Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance

open access: yesNature Communications, 2021
How ROS levels are regulated in cancer stem cells and their contribution to cancer resistance is currently not clear. Here, the authors show that prohibitin regulates mitochondrial ROS production stabilizing the peroxidase PRDX3 and this accounts for ...
Haohao Huang   +23 more
doaj   +1 more source

Foresight in clinical proteomics: current status, ethical considerations, and future perspectives [version 1; peer review: 2 approved]

open access: yesOpen Research Europe, 2023
With the advent of robust and high-throughput mass spectrometric technologies and bioinformatics tools to analyze large data sets, proteomics has penetrated broadly into basic and translational life sciences research.
Filip Mundt   +9 more
doaj   +1 more source

The New and the Old: Platform Cross-Validation of Immunoaffinity MASS Spectrometry versus ELISA for PromarkerD, a Predictive Test for Diabetic Kidney Disease

open access: yesProteomes, 2020
PromarkerD is a proteomics derived test for predicting diabetic kidney disease that measures the concentrations of three plasma protein biomarkers, APOA4, CD5L and IBP3.
Scott Bringans   +4 more
doaj   +1 more source

LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis

open access: yesNature Communications, 2021
Dynamic assembly and disassembly of primary cilia is critical for tissue development and homeostasis. Here the authors identify lysophosphatidic acid (LPA) as a physiological extracellular factor that initiates cilia disassembly through both YAP/TAZ ...
Huai-Bin Hu   +17 more
doaj   +1 more source

dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts

open access: yesNature Communications, 2022
The dia-PASEF technology uses ion mobility separation to reduce signal interferences and increase sensitivity in proteomic experiments. Here we present a two-dimensional peak-picking algorithm and generation of optimized spectral libraries, as well as ...
V. Demichev   +12 more
semanticscholar   +1 more source

Deep Visual Proteomics defines single-cell identity and heterogeneity

open access: yesNature Biotechnology, 2022
Despite the availabilty of imaging-based and mass-spectrometry-based methods for spatial proteomics, a key challenge remains connecting images with single-cell-resolution protein abundance measurements.
A. Mund   +20 more
semanticscholar   +1 more source

Foresight in clinical proteomics: current status, ethical considerations, and future perspectives [version 2; peer review: 3 approved]

open access: yesOpen Research Europe, 2023
With the advent of robust and high-throughput mass spectrometric technologies and bioinformatics tools to analyze large data sets, proteomics has penetrated broadly into basic and translational life sciences research.
Filip Mundt   +9 more
doaj   +1 more source

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