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Journal of Education, Health and Sport, 2021 Proteomics is a branch of molecular biology that deals with the identification and quantification of proteins in living objects, as well as the analysis of protein functions and their interactions. Proteomics is studied by proteins that are expressed in a given cell, tissue or organism over a period of time (under certain conditions). It is
Dolomatov, S.I. +2 more
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Proteomes, 2020 Brucella spp. are Gram negative intracellular bacteria responsible for brucellosis, a worldwide distributed zoonosis. A prominent aspect of the Brucella life cycle is its ability to invade, survive and multiply within host cells. Comprehensive approaches, such as proteomics, have aided in unravelling the molecular mechanisms underlying Brucella ...
Ansgar Poetsch +2 more
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Nature Reviews Methods Primers, 2021 The eukaryotic cell is compartmentalized into subcellular niches, including membrane-bound and membrane-less organelles. Proteins localize to these niches to fulfil their function, enabling discreet biological processes to occur in synchrony. Dynamic movement of proteins between niches is essential for cellular processes such as signalling, growth ...
Josie A. Christopher +14 more
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Proteomes: A New Proteomic Journal [PDF]
Proteomes, 2012 In the early years of proteomics, mass spectrometry served only as a technique in protein chemistry facilitating the characterization of purified proteins and mapping their posttranslational modifications (PTMs). A bit later this technique almost completely replaced Edman degradation and amino acid analysis.
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proteomics technologies: Probing the proteome [PDF]
Nature, 2003 The completion of the human genome sequence, coupled with analytical techniques such as mass spectrometry, has fuelled interest in proteomics. Diane Gershon reports.
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Nanotechnologies in Proteomics [PDF]
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Victor A. Bykov +3 more
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Proteomics of the Spermatozoon [PDF]
Balkan Journal of Medical Genetics, 2012 ABSTRACT The study of the sperm proteins is crucial for understanding its normal function and alterations in infertile patients. The sperm is a highly specialized cell with a very large flagella, with little cytoplasm and a highly condensed nucleus. The most abundant proteins in the nucleus of mammalian sperm are the protamines. The main functions
JL Ballescá, R Oliva
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009 Defects in lysosomal function have been associated with numerous monogenic human diseases typically classified as lysosomal storage diseases. However, there is increasing evidence that lysosomal proteins are also involved in more widespread human diseases including cancer and Alzheimer disease.
Torben Lübke +4 more
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Proteomics in Diagnostics [PDF]
Disease Markers, 2004 For many diseases, such as heart disease and cancer, early detection plays a pivotal role in the survival rate of the patient. When detected early, many such lethal diseases can be effectively treated with existing remedies. The difficulty remains, however, how to effectively detect such conditions at the earliest possible stage with a high enough ...
Timothy D. Veenstra, Sudhir Srivastava
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Clinica Chimica Acta, 2005 With the increase in the number of genome sequencing projects, there is a concomitant exponential growth in the number of protein sequences whose function is still unknown. Functional proteomics constitutes an emerging research area in the proteomic field whose approaches are addressed towards two major targets: the elucidation of the biological ...
MONTI, MARIA +3 more
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