Results 1 to 10 of about 490,798 (222)

Paired proteomic analysis reveals protein alterations in sun-exposed skin of professional drivers [PDF]

open access: yesScientific Reports
Professional drivers represent an ideal cohort for investigating the effects of solar radiation on skin due to their unique, asymmetric exposure to sun, a consequence of vehicle window orientations.
Amanda C. Camillo-Andrade   +5 more
doaj   +2 more sources

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

open access: yesNucleic Acids Res., 2021
The PRoteomics IDEntifications (PRIDE) database (https://www.ebi.ac.uk/pride/) is the world's largest data repository of mass spectrometry-based proteomics data.
Yasset Pérez-Riverol   +13 more
semanticscholar   +1 more source

Biomarkers of Endometriosis

open access: yesFertility & Reproduction, 2022
Background: Endometriosis is an under-recognised and often misdiagnosed chronic disease that affects one in ten women. It occurs when cells similar to those that line a uterus grow in other parts of the body, usually around the pelvis.
Kerryn L. GARRETT   +11 more
doaj   +1 more source

Deep Visual Proteomics defines single-cell identity and heterogeneity

open access: yesNature Biotechnology, 2022
Despite the availabilty of imaging-based and mass-spectrometry-based methods for spatial proteomics, a key challenge remains connecting images with single-cell-resolution protein abundance measurements.
A. Mund   +20 more
semanticscholar   +1 more source

Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance

open access: yesNature Communications, 2021
How ROS levels are regulated in cancer stem cells and their contribution to cancer resistance is currently not clear. Here, the authors show that prohibitin regulates mitochondrial ROS production stabilizing the peroxidase PRDX3 and this accounts for ...
Haohao Huang   +23 more
doaj   +1 more source

Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

open access: yesClinical Proteomics, 2023
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various disciplines of laboratory medicine to identify and quantify biomolecules in a variety of biological specimens.
A. Birhanu
semanticscholar   +1 more source

The New and the Old: Platform Cross-Validation of Immunoaffinity MASS Spectrometry versus ELISA for PromarkerD, a Predictive Test for Diabetic Kidney Disease

open access: yesProteomes, 2020
PromarkerD is a proteomics derived test for predicting diabetic kidney disease that measures the concentrations of three plasma protein biomarkers, APOA4, CD5L and IBP3.
Scott Bringans   +4 more
doaj   +1 more source

LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis

open access: yesNature Communications, 2021
Dynamic assembly and disassembly of primary cilia is critical for tissue development and homeostasis. Here the authors identify lysophosphatidic acid (LPA) as a physiological extracellular factor that initiates cilia disassembly through both YAP/TAZ ...
Huai-Bin Hu   +17 more
doaj   +1 more source

Quantitative single-cell proteomics as a tool to characterize cellular hierarchies

open access: yesNature Communications, 2021
Large-scale single-cell analyses are of fundamental importance in order to capture biological heterogeneity within complex cell systems, but have largely been limited to RNA-based technologies. Here we present a comprehensive benchmarked experimental and
E. Schoof   +9 more
semanticscholar   +1 more source

A knowledge graph to interpret clinical proteomics data

open access: yesNature Biotechnology, 2022
Implementing precision medicine hinges on the integration of omics data, such as proteomics, into the clinical decision-making process, but the quantity and diversity of biomedical data, and the spread of clinically relevant knowledge across multiple ...
Alberto Santos   +10 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy