Results 11 to 20 of about 490,947 (358)

Proteomics

open access: yesJournal of Education, Health and Sport, 2021
Proteomics is a branch of molecular biology that deals with the identification and quantification of proteins in living objects, as well as the analysis of protein functions and their interactions. Proteomics is studied by proteins that are expressed
S. Dolomatov, V. Kazakova, W. Zukow
doaj   +6 more sources

Organelle proteomics [PDF]

open access: yesCurr Protoc Protein Sci Chapter 24 (2006) Unit 24.2, 2009
This unit describes strategies for studying the proteomes of organelles, which is one example of targeted proteomics. It relies heavily on previously published units dealing with organelle preparation, protein solubilization, and proteomics techniques. A specific commentary for organelle proteomics is provided.
Lescuyer, Pierre   +3 more
arxiv   +8 more sources

Proteomics of Brucella [PDF]

open access: yesProteomes, 2020
Brucella spp. are Gram negative intracellular bacteria responsible for brucellosis, a worldwide distributed zoonosis. A prominent aspect of the Brucella life cycle is its ability to invade, survive and multiply within host cells. Comprehensive approaches, such as proteomics, have aided in unravelling the molecular mechanisms underlying Brucella ...
Ansgar Poetsch   +2 more
openaire   +6 more sources

Applied Proteomics in ‘One Health’

open access: yesProteomes, 2021
‘One Health’ summarises the idea that human health and animal health are interdependent and bound to the health of ecosystems. The purpose of proteomics methodologies and studies is to determine proteins present in samples of interest and to quantify ...
Eleni I. Katsarou   +5 more
doaj   +1 more source

Streamlined single-cell proteomics by an integrated microfluidic chip and data-independent acquisition mass spectrometry

open access: yesNature Communications, 2022
Single-cell proteomics can reveal cellular phenotypic heterogeneity and cell-specific functional networks underlying biological processes. Here, we present a streamlined workflow combining microfluidic chips for all-in-one proteomic sample preparation ...
S. Gebreyesus   +8 more
semanticscholar   +1 more source

High-throughput proteomics: a methodological mini-review

open access: yesLaboratory Investigation, 2022
Proteomics plays a vital role in biomedical research in the post-genomic era. With the technological revolution and emerging computational and statistic models, proteomic methodology has evolved rapidly in the past decade and shed light on solving ...
Miao Cui, Chao Cheng, Lanjing Zhang
semanticscholar   +1 more source

Transcriptionally imprinted glycomic signatures of acute myeloid leukemia

open access: yesCell & Bioscience, 2023
Background Acute myeloid leukemia (AML) is a genetically and phenotypically heterogeneous disease that has been suffering from stagnant survival curves for decades.
Constantin Blöchl   +4 more
doaj   +1 more source

Discovery and validation of a colorectal cancer classifier in a new blood test with improved performance for high-risk subjects

open access: yesClinical Proteomics, 2017
Background The aim was to improve upon an existing blood-based colorectal cancer (CRC) test directed to high-risk symptomatic patients, by developing a new CRC classifier to be used with a new test embodiment.
Lisa J. Croner   +8 more
doaj   +1 more source

dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts

open access: yesNature Communications, 2022
The dia-PASEF technology uses ion mobility separation to reduce signal interferences and increase sensitivity in proteomic experiments. Here we present a two-dimensional peak-picking algorithm and generation of optimized spectral libraries, as well as ...
V. Demichev   +12 more
semanticscholar   +1 more source

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