Results 11 to 20 of about 521,206 (335)
Journal of Education, Health and Sport, 2021 Proteomics is a branch of molecular biology that deals with the identification and quantification of proteins in living objects, as well as the analysis of protein functions and their interactions. Proteomics is studied by proteins that are expressed
S. Dolomatov, V. Kazakova, W. Zukow
doaj +5 more sources
Proteomes, 2020 Brucella spp. are Gram negative intracellular bacteria responsible for brucellosis, a worldwide distributed zoonosis. A prominent aspect of the Brucella life cycle is its ability to invade, survive and multiply within host cells. Comprehensive approaches, such as proteomics, have aided in unravelling the molecular mechanisms underlying Brucella ...
Ansgar Poetsch +2 more
openaire +6 more sources
High-throughput proteomics: a methodological mini-review
Laboratory Investigation, 2022 Proteomics plays a vital role in biomedical research in the post-genomic era. With the technological revolution and emerging computational and statistic models, proteomic methodology has evolved rapidly in the past decade and shed light on solving ...
Miao Cui, Chao Cheng, Lanjing Zhang
semanticscholar +1 more source
Transcriptionally imprinted glycomic signatures of acute myeloid leukemia
Cell & Bioscience, 2023 Background Acute myeloid leukemia (AML) is a genetically and phenotypically heterogeneous disease that has been suffering from stagnant survival curves for decades.
Constantin Blöchl +4 more
doaj +1 more source
Applied Proteomics in ‘One Health’
Proteomes, 2021 ‘One Health’ summarises the idea that human health and animal health are interdependent and bound to the health of ecosystems. The purpose of proteomics methodologies and studies is to determine proteins present in samples of interest and to quantify ...
Eleni I. Katsarou +5 more
doaj +1 more source
Clinical Proteomics, 2017 Background The aim was to improve upon an existing blood-based colorectal cancer (CRC) test directed to high-risk symptomatic patients, by developing a new CRC classifier to be used with a new test embodiment.
Lisa J. Croner +8 more
doaj +1 more source
Quantitative single-cell proteomics as a tool to characterize cellular hierarchies
Nature Communications, 2021 Large-scale single-cell analyses are of fundamental importance in order to capture biological heterogeneity within complex cell systems, but have largely been limited to RNA-based technologies. Here we present a comprehensive benchmarked experimental and
E. Schoof +9 more
semanticscholar +1 more source
A knowledge graph to interpret clinical proteomics data
Nature Biotechnology, 2022 Implementing precision medicine hinges on the integration of omics data, such as proteomics, into the clinical decision-making process, but the quantity and diversity of biomedical data, and the spread of clinically relevant knowledge across multiple ...
Alberto Santos +10 more
semanticscholar +1 more source
Cancer Communications, 2018 Background Our previous study demonstrated that aldolase A (ALDOA) is overexpressed in clinical human lung squamous cell carcinoma and that ALDOA promotes epithelial–mesenchymal transition and tumorigenesis.
Hailu Fu +9 more
doaj +1 more source