Results 21 to 30 of about 651,926 (331)

Proceedings of the EuBIC Winter School 2019 [PDF]

open access: yes, 2019
The 2019 European Bioinformatics Community (EuBIC) Winter School was held from January 15th to January 18th 2019 in Zakopane, Poland. This year’s meeting was the third of its kind and gathered international researchers in the field of (computational ...
Bittremieux, Wout   +9 more
core   +4 more sources

Pathway analysis and transcriptomics improve protein identification by shotgun proteomics from samples comprising small number of cells - a benchmarking study [PDF]

open access: yes, 2014
BACKGROUND: Proteomics research is enabled with the high-throughput technologies, but our ability to identify expressed proteome is limited in small samples. The coverage and consistency of proteome expression are critical problems in proteomics.
Brusic, Vladimir   +8 more
core   +5 more sources

Membrane proteins and proteomics: Love is possible, but so difficult [PDF]

open access: yes, 2009
Despite decades of extensive research, the large-scale analysis of membrane proteins remains a difficult task. This is due to the fact that membrane proteins require a carefully balanced hydrophilic and lipophilic environment, which optimum varies with ...
Adessi   +103 more
core   +4 more sources

Bacterial riboproteogenomics : the era of N-terminal proteoform existence revealed [PDF]

open access: yes, 2020
With the rapid increase in the number of sequenced prokaryotic genomes, relying on automated gene annotation became a necessity. Multiple lines of evidence, however, suggest that current bacterial genome annotations may contain inconsistencies and are ...
Fijalkowska, Daria   +3 more
core   +2 more sources

Nanotechnologies in Proteomics [PDF]

open access: yesChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Yuri D, Ivanov   +3 more
openaire   +2 more sources

Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples

open access: yesNature Communications, 2019
In-depth characterization of complex glycomes is complicated by the immense structural diversity of glycans. Here, the authors present a mass spectrometry-based strategy for untargeted, sensitive glycan profiling and identify 167 N-glycan compositions in
Guinevere S. M. Lageveen-Kammeijer   +7 more
doaj   +1 more source

Definition of valid proteomic biomarkers: a bayesian solution [PDF]

open access: yes, 2009
Clinical proteomics is suffering from high hopes generated by reports on apparent biomarkers, most of which could not be later substantiated via validation.
C.C. Holmes   +10 more
core   +1 more source

The Endogenous Metabolite Glycerophosphocholine Promotes Longevity and Fitness in Caenorhabditis elegans

open access: yesMetabolites, 2022
Metabolism and aging are closely connected. The choline derivative glycerophosphocholine (GPC), an important precursor of the neurotransmitter acetylcholine, plays important roles in brain and nervous system function.
Jia-Yu Liu   +11 more
doaj   +1 more source

Proteomics: in pursuit of effective traumatic brain injury therapeutics [PDF]

open access: yes, 2015
Effective traumatic brain injury (TBI) therapeutics remain stubbornly elusive. Efforts in the field have been challenged by the heterogeneity of clinical TBI, with greater complexity among underlying molecular phenotypes than initially conceived.
Ahmed F   +64 more
core   +2 more sources

Organelle Proteomics [PDF]

open access: yesCurrent Protocols in Protein Science, 2006
AbstractThis unit describes strategies for studying the proteomes of organelles, which is one example of targeted proteomics. It relies heavily on previously published units dealing with organelle preparation, protein solubilization, and proteomics techniques. A specific commentary for organelle proteomics is provided.
Lescuyer, Pierre   +3 more
openaire   +5 more sources

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