Results 21 to 30 of about 651,926 (331)
Proceedings of the EuBIC Winter School 2019 [PDF]
The 2019 European Bioinformatics Community (EuBIC) Winter School was held from January 15th to January 18th 2019 in Zakopane, Poland. This year’s meeting was the third of its kind and gathered international researchers in the field of (computational ...
Bittremieux, Wout +9 more
core +4 more sources
Pathway analysis and transcriptomics improve protein identification by shotgun proteomics from samples comprising small number of cells - a benchmarking study [PDF]
BACKGROUND: Proteomics research is enabled with the high-throughput technologies, but our ability to identify expressed proteome is limited in small samples. The coverage and consistency of proteome expression are critical problems in proteomics.
Brusic, Vladimir +8 more
core +5 more sources
Membrane proteins and proteomics: Love is possible, but so difficult [PDF]
Despite decades of extensive research, the large-scale analysis of membrane proteins remains a difficult task. This is due to the fact that membrane proteins require a carefully balanced hydrophilic and lipophilic environment, which optimum varies with ...
Adessi +103 more
core +4 more sources
Bacterial riboproteogenomics : the era of N-terminal proteoform existence revealed [PDF]
With the rapid increase in the number of sequenced prokaryotic genomes, relying on automated gene annotation became a necessity. Multiple lines of evidence, however, suggest that current bacterial genome annotations may contain inconsistencies and are ...
Fijalkowska, Daria +3 more
core +2 more sources
Nanotechnologies in Proteomics [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Yuri D, Ivanov +3 more
openaire +2 more sources
Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples
In-depth characterization of complex glycomes is complicated by the immense structural diversity of glycans. Here, the authors present a mass spectrometry-based strategy for untargeted, sensitive glycan profiling and identify 167 N-glycan compositions in
Guinevere S. M. Lageveen-Kammeijer +7 more
doaj +1 more source
Definition of valid proteomic biomarkers: a bayesian solution [PDF]
Clinical proteomics is suffering from high hopes generated by reports on apparent biomarkers, most of which could not be later substantiated via validation.
C.C. Holmes +10 more
core +1 more source
Metabolism and aging are closely connected. The choline derivative glycerophosphocholine (GPC), an important precursor of the neurotransmitter acetylcholine, plays important roles in brain and nervous system function.
Jia-Yu Liu +11 more
doaj +1 more source
Proteomics: in pursuit of effective traumatic brain injury therapeutics [PDF]
Effective traumatic brain injury (TBI) therapeutics remain stubbornly elusive. Efforts in the field have been challenged by the heterogeneity of clinical TBI, with greater complexity among underlying molecular phenotypes than initially conceived.
Ahmed F +64 more
core +2 more sources
AbstractThis unit describes strategies for studying the proteomes of organelles, which is one example of targeted proteomics. It relies heavily on previously published units dealing with organelle preparation, protein solubilization, and proteomics techniques. A specific commentary for organelle proteomics is provided.
Lescuyer, Pierre +3 more
openaire +5 more sources

