Results 31 to 40 of about 784,733 (395)
Transcriptionally imprinted glycomic signatures of acute myeloid leukemia
Cell & Bioscience, 2023 Background Acute myeloid leukemia (AML) is a genetically and phenotypically heterogeneous disease that has been suffering from stagnant survival curves for decades.
Constantin Blöchl +4 more
doaj +1 more source
Clinical proteomics for precision medicine: the bladder cancer case [PDF]
, 2017 Precision medicine can improve patient management by guiding therapeutic decision based on molecular characteristics. The concept has been extensively addressed through the application of –omics based approaches.
Frantzi, Maria +4 more
core +1 more source
The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics.
Mass spectrometry reviews (Print), 2020 Skyline is a freely available, open-source Windows client application for accelerating targeted proteomics experimentation, with an emphasis on the proteomics and mass spectrometry community as users and as contributors.
Lindsay K. Pino +5 more
semanticscholar +1 more source
Cancer Communications, 2018 Background Our previous study demonstrated that aldolase A (ALDOA) is overexpressed in clinical human lung squamous cell carcinoma and that ALDOA promotes epithelial–mesenchymal transition and tumorigenesis.
Hailu Fu +9 more
doaj +1 more source
Sampling the proteome by emerging single-molecule and mass-spectrometry methods [PDF]
Nat Methods 20, 339--346 (2023), 2022 Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications in the development of proteomics technologies. We examine these implications for both liquid chromatography-tandem mass spectrometry (LC-MS/MS) and single-molecule counting ...
arxiv +1 more source
Molecular & Cellular Proteomics, 2002 Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric methods based on stable isotope quantitation have shown great promise for the simultaneous and automated identification and ...
Shao-En Ong +6 more
semanticscholar +1 more source
Progress of phosphorylated proteomics in breast cancer [PDF]
Yixue xinzhi zazhi, 2020 With the development of genomics, proteomics and transcriptomics, tumor research is becoming more and more systematic and in-depth. Compared with the genome, the proteome is more complex, more active and closer to the essence of life.
Yu-Jiao DENG +3 more
doaj +1 more source
Skyline: an open source document editor for creating and analyzing targeted proteomics experiments
Bioinform., 2010 SUMMARY Skyline is a Windows client application for targeted proteomics method creation and quantitative data analysis. It is open source and freely available for academic and commercial use.
B. MacLean +9 more
semanticscholar +1 more source
Proteomics Discovery of Disease Biomarkers
Biomarker Insights, 2008 Recent technological developments in proteomics have shown promising initiatives in identifying novel biomarkers of various diseases. Such technologies are capable of investigating multiple samples and generating large amount of data end-points. Examples
Mamoun Ahram, Emanuel F. Petricoin
doaj +2 more sources
How to use 2D gel electrophoresis in plant proteomics [PDF]
Methods in Molecular Biology -Clifton then Totowa- 1072 (2014)
43-50, 2013 Two-dimensional electrophoresis has nurtured the birth of proteomics. It is however no longer the exclusive setup used in proteomics, with the development of shotgun proteomics techniques that appear more fancy and fashionable nowadays.Nevertheless, 2D gel-based proteomics still has valuable features, and sometimes unique ones, which make it often an ...
arxiv +1 more source