Results 31 to 40 of about 490,947 (358)

Cytoscape stringApp: Network analysis and visualization of proteomics data

open access: yesbioRxiv, 2018
Protein networks have become a popular tool for analyzing and visualizing the often long lists of proteins or genes obtained from proteomics and other high-throughput technologies.
N. Doncheva   +3 more
semanticscholar   +1 more source

Protein Contaminants Matter: Building Universal Protein Contaminant Libraries for DDA and DIA Proteomics

open access: yesbioRxiv, 2022
Mass spectrometry-based proteomics is constantly challenged by the presence of contaminant background signals. In particular, protein contaminants from reagents and sample handling are often abundant and almost impossible to avoid.
Ashley M. Frankenfield   +3 more
semanticscholar   +1 more source

Proteomics Discovery of Disease Biomarkers

open access: yesBiomarker Insights, 2008
Recent technological developments in proteomics have shown promising initiatives in identifying novel biomarkers of various diseases. Such technologies are capable of investigating multiple samples and generating large amount of data end-points. Examples
Mamoun Ahram, Emanuel F. Petricoin
doaj   +2 more sources

GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein

open access: yesNature Communications, 2021
Coronavirus nucleocapsid (N) protein is important for viral genome packaging and virion assembly. Here the authors show that natural chemical (-)-gallocatechin gallate (GCG) disrupts the liquid–liquid phase separation of N and inhibits SARS-CoV-2 ...
Ming Zhao   +20 more
doaj   +1 more source

In silico Proteome Cleavage Reveals Iterative Digestion Strategy for High Sequence Coverage [PDF]

open access: yesISRN Computational Biology 2014, 2014
In the post-genome era, biologists have sought to measure the complete complement of proteins, termed proteomics. Currently, the most effective method to measure the proteome is with shotgun, or bottom-up, proteomics, in which the proteome is digested into peptides that are identified followed by protein inference.
arxiv   +1 more source

Two-dimensional gel electrophoresis in proteomics: past, present and future [PDF]

open access: yesJournal of proteomics (2010) epub ahead of print, 2010
Two-dimensional gel electrophoresis has been instrumental in the birth and developments of proteomics, although it is no longer the exclusive separation tool used in the field of proteomics. In this review, a historical perspective is made, starting from the days where two-dimensional gels were used and the word proteomics did not even exist.
arxiv   +1 more source

ProteomeXchange provides globally co-ordinated proteomics data submission and dissemination

open access: yesNature Biotechnology, 2014
223 12. Li, G.-Z. et al. Proteomics 9, 1696–1719 (2009). 13. Blackburn, K., Mbeunkui, F., Mitra, S.K., Mentzel, T. & Goshe, M.B. J. Proteome Res. 9, 3621–3637 (2010). 14. Huang, X. et al. Anal. Chem. 83, 6971–6979 (2011). 15. Geiger, T., Cox, J.
J. Vizcaíno   +24 more
semanticscholar   +1 more source

proteomics technologies: Probing the proteome [PDF]

open access: yesNature, 2003
The completion of the human genome sequence, coupled with analytical techniques such as mass spectrometry, has fuelled interest in proteomics. Diane Gershon reports.
openaire   +3 more sources

Cotton proteomics: Dissecting the stress response mechanisms in cotton

open access: yesFrontiers in Plant Science, 2022
The natural environment of plants comprises a complex set of biotic and abiotic stresses, and plant responses to these stresses are complex as well. Plant proteomics approaches have significantly revealed dynamic changes in plant proteome responses to ...
George Bawa   +6 more
doaj   +1 more source

A Cross-platform Toolkit for Mass Spectrometry and Proteomics

open access: yesNature Biotechnology, 2012
Mass-spectrometry-based proteomics has become an important component of biological research. Numerous proteomics methods have been developed to identify and quantify the proteins in biological and clinical samples1, identify pathways affected by ...
Matthew Chambers   +42 more
semanticscholar   +1 more source

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