Results 41 to 50 of about 651,926 (331)
Scientific Reports, 2017 Sialylation is a glycosylation feature that occurs in different linkages at the non-reducing end of a glycan moiety, the linkage isomers are often differentially associated with various biological processes.
Guinevere S. M. Kammeijer +7 more
doaj +1 more source
Present and future of proteomics data curation at the PRIDE database [PDF]
, 2009 Significant progress has been made in improving the accessibility and utility of the large amounts of generated high-throughput proteomics data by the introduction of publicly available proteomics repositories.
Henning Hermjakob +2 more
core +2 more sources
Proteomes: A New Proteomic Journal [PDF]
Proteomes, 2012 In the early years of proteomics, mass spectrometry served only as a technique in protein chemistry facilitating the characterization of purified proteins and mapping their posttranslational modifications (PTMs). A bit later this technique almost completely replaced Edman degradation and amino acid analysis.
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Clinical Diabetes and EndocrinologyBackground There are scant data relating to prognostic biomarkers for chronic kidney disease (CKD) complicating type 1 diabetes. The aim of this study was to assess the performance of the plasma protein biomarker-based PromarkerD test developed and ...
Timothy M. E. Davis +6 more
doaj +1 more source
Identifying individuals using proteomics: are we there yet?
Frontiers in Molecular Biosciences, 2022 Multi-omics approaches including proteomics analyses are becoming an integral component of precision medicine. As clinical proteomics studies gain momentum and their sensitivity increases, research on identifying individuals based on their proteomics ...
Ivo Fierro-Monti +3 more
doaj +1 more source
Serum proteomics of active tuberculosis patients and contacts reveals unique processes activated during Mycobacterium tuberculosis infection. [PDF]
, 2020 Tuberculosis (TB) is the most lethal infection among infectious diseases. The specific aim of this study was to establish panels of serum protein biomarkers representative of active TB patients and their household contacts who were either infected (LTBI)
Anibarro, L +11 more
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis
Nature Communications, 2018 Microtubule asters originate from centrosomes but their role during interphase remains largely unknown. Here, the authors find that microtubule asters anchored by previously-uncharacterized FSD1 play a role in ciliogenesis by maintaining the dynamic ...
Hai-Qing Tu +16 more
doaj +1 more source
Progress of phosphorylated proteomics in breast cancer [PDF]
Yixue xinzhi zazhi, 2020 With the development of genomics, proteomics and transcriptomics, tumor research is becoming more and more systematic and in-depth. Compared with the genome, the proteome is more complex, more active and closer to the essence of life.
Yu-Jiao DENG +3 more
doaj +1 more source