Results 141 to 150 of about 161,310 (344)

Relationships Between Serum Vitamin D, Inflammatory Markers, and Outcomes in Non‐Critically Ill Patients With COVID‐19: A Cross‐Sectional Study

Medicine Advances, EarlyView.
Serum urea levels have been identified as a significant predictor of in‐hospital mortality in COVID‐19 patients, whereas vitamin D deficiency correlates with elevated inflammatory markers such as CRP and RPR. To better understand these associations and their implications for clinical outcomes, further large‐scale studies are warranted, emphasizing the ...
Zahra Khorasanchi, Ali Jafazadeh Esfehani, Mohammad Reza Shadmand Foumani Moghadam, Sara Shojaei Saadatqoli, Payam Sharifan, Majid Ghayour Mobarhan, Sajjad Arefinia, Afshin Roghani, Naghme Mirhossini, Masoud Pezeshki Rad, Saeid Eslami, Hamidreza Naderi, Hassan Vatanparast, Reza Rezvani   +13 more
wiley   +1 more source

A pathway toward clinical translation of hyperpolarized [1,4‐13C2,2,3‐d2]fumarate as an imaging biomarker for early cellular necrosis in vivo

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose The detection of hyperpolarized carbon‐13 (HP 13C)‐fumarate conversion to 13C‐malate using 13C‐MRSI is a biomarker for early detection of cellular necrosis. Here, we describe the translation of HP 13C‐fumarate as a novel human imaging agent, including the evaluation of biocompatibility and scaling up of the hyperpolarization methods ...
Jonathan R. Birchall, Pascal Wodtke, Ashley Grimmer, Esben S. S. Hansen, Lotte B. Bertelsen, Nikolaj Bøgh, Marta Wylot, Maria J. Zamora‐Morales, Otso Arponen, Ines Horvat‐Menih, Elizabeth C. Latimer, Fung Tan, Evita Pappa, Johann Graggaber, Joseph Cheriyan, Kelly Holmes, Matthew J. Locke, Helen Sladen, Joan Boren, Mikko I. Kettunen, Anita Chhabra, Ian B. Wilkinson, Christoffer Laustsen, Kevin Brindle, Mary A. McLean, Ferdia A. Gallagher   +25 more
wiley   +1 more source

Reversible High-Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation. [PDF]

Adv Sci (Weinh)
A calcium‐dependent, specific biorecognition between coagulation factor Xa (FXa) and zeolite is discovered. It alters the prothrombin activation pathway to a more efficient mechanism by mimicking the FXa/factor Va (FXa/FVa) interaction formed during the natural coagulation cascade.
Shi C, He M, Chen H, Wei X, Xiao L, Shang X, Shi Y, Wang Q, Yu L, Fan J.   +9 more
europepmc   +2 more sources

Risk Factors and Clinical Features of Deterioration in 739 COVID‐19 Affected Children Aged Under 14 Years in Zhuhai, China: A Multicenter, Retrospective Study

Pediatric Discovery, EarlyView.
Seven hundred and thirty‐nine children infected with SARS‐CoV‐2 in Zhuhai tend to have close‐contact aggregated morbidity within the family, with fever and cough as the main manifestations. Low age, underlying disease, some laboratory indicators, and patchy exudative changes on CT of the lungs are the windsocks of the severity of the infection ...
Ting Liu, Zhaojun Pan, Cheng Zhang, Fanlin Huang, Jundong Ding, Wenxiu Song, Yongwu Xie, Guang Lin   +7 more
wiley   +1 more source

The role of rehabilitation across the continuum of liver disease from cirrhosis to transplantation and beyond: A narrative review

PM&R, EarlyView.
Abstract Objective The authors' objective with this narrative review is to explore the impact of rehabilitative interventions at each stage of liver disease. Type Narrative review. Literature Survey Literature search conducted in Medline, Embase, and Google Scholar databases.
Laura Malmut, Sarah Eickmeyer, Leslie Rydberg, Jacqueline Neal, Julie Lanphere, Kim Barker   +5 more
wiley   +1 more source

Tutorial for Modeling Delays in Biological Systems in the NONMEM Software

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Delays in biological systems are a common phenomenon. The models for delays require specialized mathematical and numerical techniques such as transit compartments, delay differential equations (DDEs), and distributed DDEs (DDDEs). Because of mathematical complexity, DDEs and particularly DDDEs are infrequently used for modeling.
Robert J. Bauer, Wojciech Krzyzanski
wiley   +1 more source

STUDIES ON THE NATURE AND THE PURIFICATION OF THE COAGULASE-REACTING FACTOR AND ITS RELATION TO PROTHROMBIN [PDF]

, 1956
Morris Tager
openalex   +1 more source

The Dysprothrombinemias due to Arg596 Mutations: A Conundrum With No Bleeding Tendency and Venous Thrombosis due to Antithrombin Resistance [PDF]

, 2019
Cosi, E., Ferrari, S., Girolami, A., Randi, M. L.   +3 more
core   +1 more source

HUMAN PROTHROMBIN: QUANTITATIVE STUDIES ON THE PLASMA LABILE FACTOR AND THE RESTORATIVE EFFECTS OF NORMAL, HYPOFI-BRINOGENEMIC, AND HEMOPHILIC PLASMA ON THE PROTHROMBIN OF STORED PLASMA 1 [PDF]

, 1949
Benjamin Alexander, André de Vries, Eunice Addelson   +2 more
openalex   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

Small Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han, Jieyun Xu, Xinyu Guo, Lingyu Liang, Linjun Zhang, Yu Su, Wendong Gao, Qingming Tang, Lili Chen, Zhuofan Chen, Yin Xiao, Zetao Chen   +11 more
wiley   +1 more source