Results 181 to 190 of about 98,202 (223)

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu, Ziyuan Wang, Huirong Zhu, Yicun Han, Qing Ji   +4 more
wiley   +1 more source

Targeting c-Myc-p300-CARM1 complex induces ferroptosis and reduces CD8⁺ T cell exhaustion in esophageal squamous cell carcinoma. [PDF]

Int J Biol Sci
Wang Y, Li Y, Ren G, Zhou J, Chen W, Zhang K, Yu X, Yin Y, Cong J, Ma L, Zheng X, Zhao Y, Liu Z.   +12 more
europepmc   +1 more source

State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge

MedComm, Volume 7, Issue 2, February 2026.
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding, Zai Luo, Liao Zhang, Shaopeng Zhang, Renchao Zhang, Zhengjun Qiu, Chen Huang   +6 more
wiley   +1 more source

The dual fate of DYRK2 in cancer: balancing the light and dark side of tumorigenesis. [PDF]

Cancer Metastasis Rev
Suanes-Cobos L, Torres-Ramos M, Aguilera-Ventura I, Serrano-Yubero A, Calzado MA.   +4 more
europepmc   +1 more source

Spatial analysis of HPV‐associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression

The Journal of Pathology, Volume 268, Issue 2, Page 200-214, February 2026.
Abstract Cervical cancer remains the fourth most common cancer affecting women worldwide, and incidences of other HPV‐related cancers continue to rise. For the development of effective prevention strategies in high‐risk patients, we aimed to better understand the roles of inflammatory pathways and the tumour microenvironment as the main driver of ...
Gianna Pavilion, Hani Vu, Zherui Xiong, Thi Viet Trinh Dang, Blake O'Brien, Michael Walsh, Andrew Causer, Janin Chandra, Quan Nguyen, Ian H Frazer   +9 more
wiley   +1 more source

Transcriptomics Analysis of the Adipogenic Differentiation Mechanism of Bovine Adipose-Derived Neural Crest Stem Cells. [PDF]

Animals (Basel)
Zhang K, Tang X, Zhao R, Yan Y, Song X.
europepmc   +1 more source

Molecular alterations in high‐grade neuroendocrine tumors of the small intestine

The Journal of Pathology, Volume 268, Issue 2, Page 215-226, February 2026.
Abstract High‐grade neuroendocrine tumors of the small intestine are separated into two groups: well‐differentiated neuroendocrine tumors (NETs, high‐grade) and poorly differentiated neuroendocrine carcinomas (NECs). They represent very rare entities, with few molecular data available, and are very challenging to treat.
Agathe Hercent, Julien Masliah‐Planchon, David Cohen, Remy Nicolle, Jean‐Yves Scoazec, Philippe Ruszniewski, Ivan Bièche, Louis de Mestier, Anne Couvelard, Jerome Cros   +9 more
wiley   +1 more source

A case of primary cutaneous diffuse large B-cell lymphoma, leg type with <i>MYC</i> rearrangement and high BCL2 protein expression due to trisomy 18. [PDF]

Nagoya J Med Sci
Matsui Y, Katsumi A, Tanaka K, Ohara F, Motegi K, Abe A, Tamura S, Yamamoto K, Matsushita T, Adachi M, Nagata Y, Hasegawa M.   +11 more
europepmc   +1 more source

Nanobiotechnology‐Based Approaches for Uveal Melanoma Treatment

SmartMat, Volume 7, Issue 1, February 2026.
Emerging platforms for uveal melanoma combine precision drug delivery, ROS‐amplifying modalities, and nucleic acid transport to overcome ocular barriers and immunosuppressive niches. Targeted nanoparticles, virus‐like constructs, and injectable depots enable localized activation, controlled release, and gene‐level reprogramming.
Nadezhda A. Pechnikova, Ioannis Iliadis, Malamati Poimenidou, Chrysi Patsidou, Maria Zafeiriou‐Chatziefraimidou, Diamantis D. Almaliotis, Ioannis T. Tsinopoulos, Ivan V. Zelepukin, Alexey V. Yaremenko   +8 more
wiley   +1 more source

VRK2 targeting potentiates anti-PD-1 immunotherapy in hepatocellular carcinoma through MYC destabilization. [PDF]

Nat Commun
Su C, Liao Z, Mo J, Liu F, Wang W, Zhang H, Zhang H, Liu Y, Pan Y, Zhu H, Chen X, Zhang Z, Zhu P, Zhang B.   +13 more
europepmc   +1 more source