Results 11 to 20 of about 57,684 (329)

Identification of Candidate mRNA Genes and Their Potential MicroRNA Targets in Lung Cancer Induced by Smoking Tobacco

open access: yesFrontiers in Bioscience-Scholar, 2023
Background: Smoking is considered the single highest risk factor for lung cancer and has been suggested to be associated with accelerated somatic mutations in respiratory mucosa that lead to the development of lung cancer.
Amresh Kumar Mishra   +2 more
doaj   +1 more source

Characterization of Leukemia-Inducing Genes Using a Proto-Oncogene/Homeobox Gene Retroviral Human cDNA Library in a Mouse In Vivo Model. [PDF]

open access: yesPLoS ONE, 2015
The purpose of this research is to develop a method to screen a large number of potential driver mutations of acute myeloid leukemia (AML) using a retroviral cDNA library and murine bone marrow transduction-transplantation system.
Su Hwa Jang, Sohyun Lee, Hee Yong Chung
doaj   +1 more source

ProtoPred: Advancing Oncological Research Through Identification of Proto-Oncogene Proteins

open access: yesIEEE Access, 2021
Proto-oncogenes are the genes that have the potential to transform normal cells into cancer cells as a result of mutations. They usually contain encoding of proteins whose function is to inhibit cell differentiation, stimulate cell division, and prevent ...
Sharaf J. Malebary   +2 more
doaj   +1 more source

Syndrome in question [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
Costello syndrome (CS) is a rare genetic disorder, first described by Costello in 1971, caused by mutations in the HRAS proto-oncogene. Clinical findings include facial dysmorphism, skin disorders, cognitive impairment, cardiac and musculoskeletal ...
Isy Lima Peixoto   +5 more
doaj   +1 more source

Proto-oncogene Protein Sequence Classification using RNN and CNN with Attention Mechanism [PDF]

open access: yes, 2023
The fundamental tool for uncontrolled tumour progression is the lack of regulatory capacity of tumour suppression genes (TSG) and mutations in proto-oncogenes (OG). Even though tumour is a diverse complex of several diseases, discovering possibilities of
M.Vijayalakshmia, et al.
core   +2 more sources

Genetic Determinants of Feline Leukemia Virus-Induced Multicentric Lymphomas [PDF]

open access: yes, 1995
Three discrete forms of feline leukemia virus (FeLV)-associated lymphoma have been described clinically: (1) thymic, (2) alimentary, and (3) multicentric.
ATHAS, GRACE B.   +4 more
core   +1 more source

Proto‐oncogenes and spermatogenesis [PDF]

open access: yesInternational Journal of Andrology, 1989
Expression des protooncogenes dans l'epithelium seminifere et au cours de la spermatogenese; implication dans la regulation du developpement des cellules ...
openaire   +3 more sources

Hypoxic-ischemic encephalopathy: facts and insights [PDF]

open access: yes, 2005
Asphyxia may cause a hypoxic-ischemic encephalopathy due to an insufficient supply of oxygenated blood to the brain, which leads to a cerebral palsy. The transition state between both is called neonatal encephalopathy.
Braems, Geert
core   +2 more sources

C-fos and c-jun Proto-Oncogene Expression Is Decreased in Psoriasis: an In Situ Quantitative Analysis [PDF]

open access: yes, 1991
Psoriasis is a common, sometimes sevcre, non-malignant skin disease characterized by hyperproliferation and abnormal differentiation of keratinocytes. Because proto-oncogenes are implicated in both cell proliferation and differentiation, their expression
Basset-Séguin, Nicole.   +5 more
core   +1 more source

Molecular Pathogenesis and Targeted Therapies in Well-Differentiated Thyroid Carcinoma [PDF]

open access: yesEndocrinology and Metabolism, 2014
Four proto-oncogenes commonly associated with well-differentiated thyroid carcinoma, rearranged during transfection (RET)/papillary thyroid cancer, BRAF, RAS, and PAX8/peroxisome proliferator activated receptor-γ, may carry diagnostic and prognostic ...
Jung Guk Kim
doaj   +1 more source

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