Expression profile of CREB knockdown in myeloid leukemia cells. [PDF]
, 2008 BackgroundThe cAMP Response Element Binding Protein, CREB, is a transcription factor that regulates cell proliferation, differentiation, and survival in several model systems, including neuronal and hematopoietic cells.
Cheng, Jerry C +6 more
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Plag1 and Plagl2 have overlapping and distinct functions in telencephalic development
Biology Open, 2018 The Plag gene family has three members; Plagl1/Zac1, which is a tumor suppressor gene, and Plag1 and Plagl2, which are proto-oncogenes. All three genes are known to be expressed in embryonic neural progenitors, and Zac1 regulates proliferation, neuronal ...
Lata Adnani +7 more
doaj +1 more source
E6 Protein Expressed by High-Risk HPV Activates Super-Enhancers of the EGFR and c-MET Oncogenes by Destabilizing the Histone [PDF]
, 2018 The high-risk (HR) human papillomaviruses (HPV) are causative agents of anogenital tract dysplasia and cancers and a fraction of head and neck cancers.
Chen, Xiaohua +13 more
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Expression of c-myc and c-fms oncogenes in trophoblastic cells in hydatidiform mole and normal human placenta [PDF]
, 1993 Aims: To compare the expression of c-myc and c-fms proto-oncogenes in the placenta and hydatidiform mole. Methods: Twelve hydatidiform moles and six induced abortion cases were collected. c-myc and c-fms proto-oncogene expression was analysed by northern
Cheung, ANY +5 more
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High-Resolution Three-Dimensional NMR Structure Of The KRAS Proto-Oncogene Promoter Reveals Key Features Of A G-Quadruplex Involved In Transcriptional Regulation [PDF]
, 2017 Non-canonical base pairing within guanine-rich DNA and RNA sequences can produce G-quartets, whose stacking leads to the formation of a G-quadruplex (G4).
Ivashchenko, S. +5 more
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Chronic lymphocytic leukaemia: contemporary conceptions of etiology, pathogenesis and peculiarities of clinical manifestations (review) [PDF]
Саратовский научно-медицинский журнал, 2011 The research work presents an analysis of literature review and results of investigations on the problems of etiology, pathogenesis, classification and peculiarities of clinical manifestations of chronic lymphocytic leukaemia.
Chesnokova N.P. +2 more
doaj
Proto-oncogene c-jun and c-fos messenger RNAs increase in the liver of carnitine-deficient juvenile visceral steatosis (jvs) mice [PDF]
, 1992 We determined the mRNA levels of c-jun and c-fos in the liver of C3H-H-2° jvs mice. Both were higher in jvs mice than in normal mice. The level of c-jun mRNA increased gradually after birth, but in the control mice there was almost no change. In addition,
Nakagawa, Kyoko +2 more
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Regulation of Proto-oncogenes Expression in Developmental Epilepsy [PDF]
, 2003 Seizures cause selective neuronal cell loss in vulnerable regions such as the hippocampus, cortex, thalamus or substantia nigra (SN) in human or experimental animals.
Shafiei, Mahnoush
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Aldehyde dehydrogenase-1a1 induces oncogene suppressor genes in B cell populations [PDF]
, 2013 The deregulation of B cell differentiation has been shown to contribute to autoimmune disorders, hematological cancers, and aging. We provide evidence that the retinoic acid-producing enzyme aldehyde dehydrogenase 1a1 (Aldh1a1) is an oncogene suppressor ...
Alder, H. +9 more
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Role of DNA methylation in cancer development and its clinical applications
Clinical and Translational Discoverymethyltransferase gene (DNA) methylation is a key process in epigenetic modification. This transformation leads to genomic instability that creates an impact on gene expression.
Swarup Sonar +3 more
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