Results 81 to 90 of about 226,605 (267)

T cell recognition of transforming proteins encoded by mutated ras proto-oncogenes.

Journal of Immunology, 1991
Activated ras proto-oncogenes contribute to the pathogenesis of many animal and human malignancies. ras proto-oncogenes are generally activated by point mutations within codons 12 or 61, which result in the expression of ras protein (p21) bearing ...
D. Peace, Wei Chen, H. Nelson, M. Cheever   +3 more
semanticscholar   +1 more source

Carcinogénesis bucal

Correo Científico Médico, 2020
El cáncer bucal es una neoplasia maligna multifactorial donde la predisposición genética a la enfermedad se relaciona con factores del ambiente para desarrollar un cáncer con evolución lenta y signos inespecíficos.
Raciel Jorge Sánchez Sánchez, Cristian Roberto Sigcho Romero, Alejandro Jesús Bermúdez Garcell, Nilvia Bienvenida Serrano Gámez, Rolando Teruel Ginés   +4 more
doaj  

Effect of (R)-(+) Pulegone on Ovarian Tissue; Correlation with Expression of Aromatase Cyp19 and Ovarian Selected Genes in Mice

Cell Journal, 2018
Objective Pulegone (PGN) is a monoterpene ketone, whose metabolites exert several cytotoxic effects in various tissues. The present study was conducted in order to evaluate the (R)-(+) PGN-induced alterations in ovarian aromatization, proto-oncogenes ...
Rohiyeh Souldouzi, Mazdak Razi, Ali Shalizar Jalali, Ghader Jalilzadeh-Amin, Saeedeh Amani   +4 more
doaj   +1 more source

Strong and prolonged induction of c-jun and c-fos proto-oncogenes by photodynamic therapy.

British Journal of Cancer, 1996
Photodynamic therapy (PDT) is currently under investigation in phase II and III clinical studies for the treatment of tumours in superficial localisations.
G. Kick, G. Messer, G. Plewig, P. Kind, A. Goetz   +4 more
semanticscholar   +1 more source

Expression of proto-oncogenes and gene mutation of sarcomeric proteins in patients with hypertrophic cardiomyopathy.

Circulation Research, 1998
Several mutations of cardiac beta-myosin heavy chain (beta-MHC) gene were reported in patients with hypertrophic cardiomyopathy (HCM). Involvement of proto-oncogenes has been shown in the mechanism of experimental cardiac hypertrophy.
H. Kai, Akihiko Muraishi, Yuji Sugiu, Hirohumi Nishi, Y. Seki, F. Kuwahara, Akinori Kimura, Hirohisa Kato, Tsutomu Imaizumi   +8 more
semanticscholar   +1 more source

Low Frequency of Rearrangements of the ret and trk Proto‐oncogenes in Japanese Thyroid Papillary Carcinomas

Japanese journal of cancer research : Gann, 1992
We investigated the frequency of rearrangements of the ret and trk proto‐oncogenes in Japanese thyroid tumors. DNAs from 38 thyroid papillary carcinomas and 14 follicular adenomas were analyzed by Southern blotting.
W. Wajjwalku, S. Nakamura, Y. Hasegawa, K. Miyazaki, Y. Satoh, H. Funahashi, M. Matsuyama, Masahide Takahashi   +7 more
semanticscholar   +1 more source

Helicobacter pylori Activates Mitogen-activated Protein Kinase Cascades and Induces Expression of the Proto-oncogenes c-fos and c-jun *

Journal of Biological Chemistry, 2000
Helicobacter pylori is an etiological agent in the development of mucosa-associated lymphoid tissue lymphoma and gastric adenocarcinoma. Patients infected with H.
T. Meyer-ter-Vehn, A. Covacci, M. Kist, H. Pahl   +3 more
semanticscholar   +1 more source

The epigenetic factor BORIS/CTCFL regulates the NOTCH3 gene expression in cancer cells. [PDF]

, 2014
Aberrant upregulation of NOTCH3 gene plays a critical role in cancer pathogenesis. However, the underlying mechanisms are still unknown. We tested here the hypothesis that aberrant epigenetic modifications in the NOTCH3 promoter region might account for ...
CAIAFA, Paola, CHIARETTI, sabina, CIALFI, Samantha, CICCARONE, FABIO, Claudio Passananti, NOCCHIA, DANIELA, PALERMO, ROCCO, SCREPANTI, Isabella, TALORA, Claudio, ZAMPIERI, Michele   +9 more
core   +3 more sources

Adefovir Dipivoxil as a Therapeutic Candidate for Medullary Thyroid Carcinoma: Targeting RET and STAT3 Proto-Oncogenes. [PDF]

Cancers (Basel), 2023
Alqahtani T, Kumarasamy V, Alghamdi SS, Suliman RS, Bin Saleh K, Alrashed MA, Aldhaeefi M, Sun D.   +7 more
europepmc   +1 more source

Aneuploidías del cromosoma 17 y deleción del Gen TP53 en neoplasias hematológicas

Iatreia, 2006
La oncogénesis es considerada un proceo de múltiples etapas, en donde los factores genéticos son esenciales para su origen y desarrollo; se afectan principalmente dos grandes grupos de genes; se afectan principalmente dos grandes grupos de genes: los ...
Carlos Mario Muñetón Peña, José Luis Ramírez Castro, Gonzálo Vásquez Palacio, Gloria Ramírez Gaviria, Luis Fernando Isaza Jiménez, Juan Carlos Herrera Patiño   +5 more
doaj