Safety assessment of membrane-associated protoporphyrinogen IX oxidase from Enterobacter cloacae expressed in genetically modified crops [PDF]
GM Crops & FoodCrops tolerant to protoporphyrinogen IX oxidase (PPO)-inhibiting herbicides were developed by expressing an herbicide insensitive PPO, a membrane-associated protein from Enterobacter cloacae. E.
Cunxi Wang +9 more
doaj +2 more sources
A Comprehensive Molecular Modeling Study of Phenyltriazolinone Derivatives as Protoporphyrinogen Oxidase (PPO) Inhibitors. [PDF]
Chem BiodiversAn integrated computational strategy (QSAR, docking, molecular dynamics, and PBSA) identified novel phenyltriazolinone‐based PPO inhibitors with enhanced predicted activity. Compound P7 emerged as the most promising candidate, while P4 and P5 also outperformed sulfentrazone.
de Faria AC +3 more
europepmc +2 more sources
Proteomics analysis of nitrogen stress on the influence of carbon and nitrogen metabolism of flue-cured tobacco [PDF]
BMC GenomicsNitrogen stress is the main abiotic stress factor affecting the carbon and nitrogen balance of flue-cured tobacco. Using tandem mass tag (TMT) proteomics, we identified 157 differentially expressed proteins (DEPs) under low nitrogen (LN, 60 kg/hm2; 65 ...
Xinwang Zhang +6 more
doaj +2 more sources
A Rare Clinical Presentation of Variegate Porphyria. [PDF]
Mol Genet Genomic MedWGS redirected the diagnostic focus, underscoring the complex interplay between porphyria and a potential MYMK‐related neuromuscular phenotype. ABSTRACT Background Variegate porphyria is a rare heme biosynthesis disorder caused by pathogenic variants in the PPOX gene.
Viakhireva I +5 more
europepmc +2 more sources
Fendioxypyracil, a new and systemic PPO-inhibiting herbicide for X-spectrum weed control. [PDF]
Pest Manag SciThis graphical abstract presents the discovery and synthesis of PPO herbicide structures with a central pyridine core, showing molecular conformations, dose–response inhibition curves for PPO1 and PPO2, and comparative weed and grass control efficacy of fendioxypyracil versus other herbicides in greenhouse and field trials.
Seiser T +8 more
europepmc +2 more sources
Tolerance of Brazilian bean cultivars to protoporphyrinogen oxidase inhibiting-herbicides
Journal of Plant Protection Research, 2021 The high sensitivity of beans to herbicides is one of the limiting factors regarding the management of dicot weeds in bean crops. Protoporphyrinogen oxidase (PPO) inhibition is an important mechanism of action that has unregistered molecules with ...
Antonio Pedro Brusamarello +7 more
doaj +1 more source
INHERITANCE OF RESISTANCE TO PROTOPORPHYRINOGEN OXIDASE INHIBITOR HERBICIDES IN WILD POINSETTIA [PDF]
Planta Daninha, 2016 Weed resistance to herbicides is a major global problem for agriculture. In recent years, the increased use of herbicides, without proper planning, has led to a large increase in the number of cases of weed biotypes that are resistant to one or more ...
A.P. BRUSAMARELLO +4 more
doaj +1 more source
Characteristics of murine protoporphyrinogen oxidase [PDF]
Protein Science, 1992 AbstractProtoporphyrinogen oxidase (EC 1.3.3.4) (PPO) is the penultimate enzyme of the heme biosynthetic pathway. Mouse PPO has been purified in low yield and kinetically characterized by this laboratory previously. A new more rapid purification procedure is described herein, and with this protein we detect a noncovalently bound flavin moiety.
K L, Proulx, H A, Dailey
openaire +2 more sources
Environmental and physiological factors that affect the efficacy of herbicides that inhibit the enzyme protoporphyrinogen oxidase: a literature review [PDF]
Planta Daninha, 2014 Herbicides that inhibit the enzyme protoporphyrinogen oxidase (PROTOX) are usually effective to control dicotyledonous weeds and their agronomic efficacy is affected by environmental and physiological factors. The objective of this review is to summarize
F.O. Matzenbacher +3 more
doaj +1 more source
Lesion mimic mutant 8 balances disease resistance and growth in rice
Frontiers in Plant Science, 2023 Lesion-mimic mutants (LMM) spontaneously produce necrotic spots, a process not affected by environmental stress or pathogen infection. In this study, we identified a LMM, lesion mimic mutant 8 (lmm8) in rice (Oryza sativa). The lmm8 mutant produces brown
Mengcan Zhao +11 more
doaj +1 more source