Results 31 to 40 of about 93 (92)

Chromogranin A-like proteins in the secretory granules of a protozoan, Paramecium tetraurelia.

Journal of Biological Chemistry, 1987
The ciliate protozoan Paramecium tetraurelia produces secretory granules (trichocysts) which release needle-like structures composed of small, acidic proteins. Using antibodies against isolated chromogranin A (CGA) and against trichocyst proteins, we found cross-reactive proteins in chromaffin granules and trichocysts.
R H Angeletti, E Ling, David L. Nelson, Joan B. Peterson   +3 more
openaire   +3 more sources

Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei [PDF]

Frontiers in Pharmacology, 2015
Drug resistance in pathogenic protozoa is very often caused by changes to the 'transportome' of the parasites. In Trypanosoma brucei, several transporters have been implicated in uptake of the main classes of drugs, diamidines and melaminophenyl arsenicals. The resistance mechanism had been thought to be due to loss of a transporter known to carry both
Jane Claire Munday, Luca eSettimo, Luca eSettimo, Harry P de Koning   +3 more
openaire   +5 more sources

Discospondylitis as a consequence of jugular vein septic thrombophlebitis in a Standardbred gelding

Equine Veterinary Education, EarlyView.
Summary This report describes the identification of C7‐T1 discospondylitis on myelography and confirmed on postmortem computed tomography and necropsy in a 4‐year‐old Standardbred gelding as the consequence of jugular vein catheterisation and secondary septic thrombophlebitis. Staphylococcus aureus was isolated from both sites.
F. Payette, J. A. Demchur, K. W. Bills, D. G. Levine, A. L. Johnson   +4 more
wiley   +1 more source

Evolutionary Origin of the Protozoan Parasites Histone-like Proteins (HU)

In Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation, 2008
The histone-like proteins (HU) belong to a family of DNA architectural proteins that stabilize nucleoprotein complexes. We found a putative HU protein (TgGlmHMM_3045) in Toxoplasma gondii genome that was homologous to the bacterial HU protein. This putative sequence was located in the scaffold TGG_995361 of the chromosome 10. The sequence included the
Aylan Farid, Arenas, Andrés J Gutierrez, Escobar, Jorge Enrique, Gómez-Marin   +2 more
openaire   +2 more sources

Spinal ataxia and computed tomography findings in a Poitou donkey affected with congenital occipitoatlantoaxial malformation

Equine Veterinary Education, EarlyView.
Summary A 3‐year‐old Poitou donkey was referred for a computed tomography (CT) examination of the cervical spine due to acute deterioration of spinal ataxia. Neurological assessment revealed restricted neck mobility, hypermetria and circumduction of all limbs, indicating a grade 2 out of 5 ataxia.
M. Mikic, F. Frers, L. Wittenberg‐Voges, M. Hellige   +3 more
wiley   +1 more source

Novel Features of a PIWI-Like Protein Homolog in the Parasitic Protozoan Leishmania

PLoS ONE, 2012
In contrast to nearly all eukaryotes, the Old World Leishmania species L. infantum and L. major lack the bona fide RNAi machinery genes. Interestingly, both Leishmania genomes code for an atypical Argonaute-like protein that possesses a PIWI domain but lacks the PAZ domain found in Argonautes from RNAi proficient organisms.
Carole Dumas, Mukesh Samant, Prasad K. Padmanabhan, Barbara Papadopoulou, Martin J. Simard, Annie Rochette   +5 more
openaire   +5 more sources

A case of visceral leishmaniasis mimicking connective tissue disease

Rheumatology &Autoimmunity, EarlyView.
Yucui Li, Hongxia Yang, Tingzi Zhao, Ke Xu, Liyun Zhang   +4 more
wiley   +1 more source

A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains

The FEBS Journal, EarlyView.
Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley   +1 more source

Adverse impact of acute Toxoplasma gondii infection on human spermatozoa

The FEBS Journal, EarlyView.
Toxoplasma gondii tachyzoites injected intraperitoneally crossed the blood‐testes barrier, appearing in testes/epididymis by day 6 post‐infection. In vitro exposure caused increased sperm necrosis/apoptosis and structural damage to heads/tails. Immunofluorescence and SEM revealed tachyzoites attaching to sperm tails, inducing twisting/detachment, and ...
Lisbeth Rojas‐Barón, Leandro Tana‐Hernandez, Mireille H. Nguele Ampama, Raúl Sanchéz, Ulrich Gärtner, Florian M. E. Wagenlehner, Christian Preußer, Elke Pogge von Strandmann, Carlos Hermosilla, Anja Taubert, María E. Francia, Zahady D. Velasquez   +11 more
wiley   +1 more source

Malignant Mixed Irido‐Melanophoroma in a Betta splendens with Concurrent Mycobacterium chelonae Isolation—A Case Report

Journal of Fish Diseases, EarlyView.
ABSTRACT A 10‐month‐old intact male blue Siamese fighting fish (Betta splendens) was presented to the Purdue University Small Animal Hospital with multiple bilateral masses on the caudal flank. Comprehensive evaluation using impression cytology, histopathology and transmission electron microscopy (TEM) revealed a tumour composed of a mixed‐cell ...
Zi An Yu, Lorraine A. Corriveau, Joanne B. Messick   +2 more
wiley   +1 more source