Results 51 to 60 of about 93 (92)

ILC2 Diversity, Location, and Function in Pulmonary Disease

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma, Uryan I. Can, R. Lee Reinhardt   +2 more
wiley   +1 more source

The Future of Pathogen Detection in Aquaculture: Miniature Labs, Field‐Compatible Assays, environmental DNA and RNA, CRISPR and Metatranscriptomics

Aquaculture, Fish and Fisheries, Volume 5, Issue 3, June 2025.
ABSTRACT Inland recirculating aquaculture is a thriving food industry providing sustainable and locally sourced high‐quality protein. However, its expansion is accompanied by emerging challenges regarding the spread of pathogens and diseases. Detection and management of pathogens in aquaculture remain underdeveloped compared to other animal farming ...
Jessica Rieder, Anastasiia Berezenko, Alexandra Meziti, Irene Adrian‐Kalchhauser   +3 more
wiley   +1 more source

Cost‐Effective Nanosensor Solutions for Ultra‐Sensitive Detection of Metronidazole

Analytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Metronidazole (MNZ) is a widely used imidazole antibiotic effective against bacterial and protozoal infections, including giardiasis, trichomoniasis, bacterial vaginosis, and antibiotic‐associated colitis. However, prolonged and excessive use of MNZ can lead to serious side effects, such as peripheral neuropathies, toxicity, and optic ...
Ahmad Mobed, Mohammad Darvishi, Vahid Alivirdiloo, Sara Ebrahimi, Mobasher Hajiabbasi, Farhood Ghazi, Hamidreza Hassanzadeh Khanmiri   +6 more
wiley   +1 more source

A novel EF-hand calcium-binding protein in the flagellum of the protozoan Tritrichomonas suis

Parasitology, 2001
The cloning and characterization of Ts-p41, an EF-hand calcium-binding protein of the protozoan parasite Tritrichomonas suis is described. A T. suis cDNA library was screened with monospecific antibodies affinity purified on an immunoreactive 41 kDa antigen in a Triton X-114 membrane-protein fraction.
Felleisen, R S, Hemphill, Andrew, Gottstein, Bruno   +2 more
openaire   +3 more sources

Can Unicellular Organisms Sequester a Germline? The Yeast‐Germline Hypothesis

BioEssays, Volume 47, Issue 6, June 2025.
Asymmetrical inheritance of template‐DNA and copy‐DNA strands during mitosis can reduce the number of mutant cells. This requires that cells continuing to divide inherit the “immortal” template‐DNA, while their daughter cells become quiescent and inherit copy‐DNA strands.
Bhavya Sree Vadlamudi, Duur K. Aanen
wiley   +1 more source

Native synthetic microbial communities enhance zha‐chili by boosting the fermentation capacity of indigenous microorganisms

iMetaOmics, Volume 2, Issue 2, June 2025.
Traditional fermented foods in synthetic microbial communities (SynComs). We simulated the production of zha‐chili, a traditional fermented food, in the laboratory, intending to address the following questions: How are SynComs constructed, and what is the effect of inoculation with SynComs on the quality of zha‐chilli? How does inoculation with SynComs
Hongye Shen, Chuanyu Du, Shu Jiang, Weiwei Dong, Jinshan Li, Yongmei Hu, Nan Peng, Shumiao Zhao   +7 more
wiley   +1 more source

Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies

MedComm, Volume 6, Issue 6, June 2025.
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen, Yixiao Yuan, Fan Zhou, Lihua Li, Jun Pu, Yong Zeng, Xiulin Jiang   +6 more
wiley   +1 more source

Molecular characterization of a synthetic neutralizing antibody targeting p67 of Theileria parva

Protein Science, Volume 34, Issue 6, June 2025.
Abstract The Theileria parva sporozoite surface antigen p67 is a target of the bovine humoral immune response that generates antibodies capable of providing protection against subsequent infection. As a result, p67 has been the subject of efforts aimed at the development of an anti‐sporozoite subunit vaccine.
Shane Miersch, Alex U. Singer, Chao Chen, Fred Fellouse, Anupriya Gopalsamy, Luciano Silva e Costa, Anna Lacasta, Hannah Chege, Naomi Chege, Vishvanath Nene, Sachdev S. Sidhu   +10 more
wiley   +1 more source

Land Use Change and Infectious Disease Emergence

Reviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli, Paolo D’Odorico, Nikolas Galli, Reju S. John, Renata L. Muylaert, Monia Santini, David T. S. Hayman   +6 more
wiley   +1 more source

The efficacy of toltrazuril for prevention of oriental theileriosis (Theileria orientalis Ikeda genotype) in Friesian calves

Australian Veterinary Journal, Volume 103, Issue 6, Page 322-329, June 2025.
The aim of this non‐blinded, randomised, controlled study was to determine the efficacy of toltrazuril for the prevention of oriental theileriosis in calves. Thirty calves were infected with Theileria orientalis Ikeda genotype through the application and retention of infected female bush ticks (Haemaphysalis longicornis). 15 Group 1 calves were treated
SG de Burgh, DL Emery
wiley   +1 more source