Results 51 to 60 of about 11,109 (130)

Evasion of immune responses by Trypanosoma cruzi, the etiological agent of Chagas disease

Brazilian Journal of Medical and Biological Research, 2011
Infection with the protozoan parasite Trypanosoma cruzi leads to Chagas disease, which affects millions of people in Latin America. Infection with T. cruzi cannot be eliminated by the immune system.
G.A. DosReis
doaj   +3 more sources

Risk Ranking of Microbiological Hazards in Food (2015–2019)

Food Risk Assess Europe, Volume 4, Issue 3, July 2026.
Abstract Microbiological food safety risks arise from pathogens that can contaminate food at different points along the food chain. Exposure to these hazards can result in illnesses that can vary widely in severity and duration, depending on factors such as the specific pathogen involved, the amount of the pathogen ingested, and the susceptibility of ...
Ms Chloe Glennon, Lisa O’Connor, Kevin Burke, Lauren Russell, Shaun Smith, Declan Bolton, Theo de Waal, Patricia Garvey, Montserrat Gutierrez, Noel McCarthy, Lois O’Connor, Helen O’Shea, Geraldine Duffy   +12 more
wiley   +1 more source

Overview of Commercial Vaccines Against Canine Visceral Leishmaniasis: Current Landscape and Future Directions

Pathogens
Visceral leishmaniasis is a zoonosis commonly caused in Brazil by the parasite Leishmania infantum. This protozoan parasite can infect several species of mammals, with dogs being the main reservoir in urban areas.
Josiane Aparecida Martiniano de Pádua, Diego Ribeiro, Victor Freire Ferreira de Aguilar, Tuane Ferreira Melo, Lilian Lacerda Bueno, Ana Laura Grossi de Oliveira, Ricardo Toshio Fujiwara, Kelly Moura Keller   +7 more
doaj   +1 more source

Prospects and Challenges of Genetically Modified Live-Attenuated Leishmania Vaccines

Zoonoses
Leishmaniases are transmitted by the protozoan parasite Leishmania through the bites of infected sandflies. Despite the availability of various medications, rising resistance and toxicity levels underscore the urgent need to explore and create a ...
Suman Karmakar, Mousumi Das, Monalisa Ray, Soumyadip Mukherjee, Sanhita Ghosh, Kamalika Roy, Chiranjib Pal   +6 more
doaj   +1 more source

Biomarkers of safety and immune protection for genetically modified live attenuated Leishmania vaccines against visceral leishmaniasis-Discovery and implications

Frontiers in Immunology, 2014
Despite intense efforts there is no safe and efficacious vaccine against visceral leishmaniasis, which is fatal and endemic in many tropical countries. A major shortcoming in the vaccine development against blood borne parasitic agents such as Leishmania
Sreenivas eGannavaram, Ranadhir eDey, Kumar eAvishek, Angamuthu eSelvapandiyan, Poonam eSalotra, Hira eNakhasi   +5 more
doaj   +1 more source

Extracellular Vesicles of Giardia duodenalis: Unravelling Their Virulence Factors and Potential to Induce Protection Against Experimental Giardiasis

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo, Argüello‐García Raúl, Ortiz‐Lozano Dalia, Salazar‐Villatoro Lizbeth, Pech‐Santiago Edar Onam, Espinosa‐Cantellano Martha, Hernández‐Cueto Daniel, Silva‐Olivares D. Angélica, Betanzos Abigail, Ortega‐Pierres M. Guadalupe   +9 more
wiley   +1 more source

A Self-Assembling Pfs230D1-Ferritin Nanoparticle Vaccine Has Potent and Durable Malaria Transmission-Reducing Activity

Vaccines
Malaria is caused by eukaryotic protozoan parasites of the genus Plasmodium. There are 249 million new cases and 608,000 deaths annually, and new interventions are desperately needed.
Nichole D. Salinas, Rui Ma, Holly McAleese, Tarik Ouahes, Carole A. Long, Kazutoyo Miura, Lynn E. Lambert, Niraj H. Tolia   +7 more
doaj   +1 more source

Synthetic biology for combating leishmaniasis

Frontiers in Microbiology
Leishmaniasis is a neglected tropical disease caused by protozoan parasites of the Leishmania genus. Despite the efforts to control and treat the disease, it still remains a major public health problem in many countries.
Shweta Khandibharad, Shailza Singh
doaj   +1 more source

Babesia bovis Enolase Is Expressed in Intracellular Merozoites and Contains B-Cell Epitopes That Induce Neutralizing Antibodies In Vitro

Vaccines
Background: Bovine babesiosis, caused by the tick-borne apicomplexan parasite Babesia spp., is an economically significant disease that threatens the cattle industry worldwide.
Alma Cárdenas-Flores, Minerva Camacho-Nuez, Massaro W. Ueti, Mario Hidalgo-Ruiz, Angelina Rodríguez-Torres, Diego Josimar Hernández-Silva, José Guadalupe Gómez-Soto, Masahito Asada, Shin-ichiro Kawazu, Alma R. Tamayo-Sosa, Rocío Alejandra Ruiz-Manzano, Juan Mosqueda   +11 more
doaj   +1 more source

Emerging role of γδ T cells in vaccine‐mediated protection from infectious diseases

Clinical & Translational Immunology, 2019
γδ T cells are fascinating cells that bridge the innate and adaptive immune systems. They have long been known to proliferate rapidly following infection; however, the identity of the specific γδ T cell subsets proliferating and the role of this ...
Kathleen W Dantzler, Lauren de laParte, Prasanna Jagannathan   +2 more
doaj   +1 more source