Results 21 to 30 of about 16,784 (210)

Longitudinal comparison of HIV‐1 plasma viral load and cellular proviral load [PDF]

Journal of the International AIDS Society, 2014
IntroductionThe goal of antiretroviral treatment (ART) in HIV‐1 infection is the permanent suppression of plasma viral load (pVL) below the currently existing limit of detection of 50 copies/mL (DAIG HIV‐therapy guidelines). Therefore, treatment effectiveness is based on pVL.
Schweitzer, Finja, Mikkola, Visa, Timmen-Wego, Monika, Jensen, Björn, Fätkenheuer, Gerd, Kaiser, Rolf   +5 more
openaire   +2 more sources

Bovine leukemia virus proviral load in naturally-infected animals [PDF]

Retrovirology, 2011
Due to the high prevalence of Bovine Leukemia Virus (BLV) in argentinean dairy herds, classical control based on the individual level of infection do not constitute a feasible strategy. An approach based on selective segregation of animals according to their peripheral-blood proviral load (PVL) could be a practical alternative.
Alvarez, Irene, Gutiérrez, Gerónimo, Politzki, Romina, González, Cintia, Martínez, Cecilia, Gammella, Mariela, Trono, Karina   +6 more
openaire   +1 more source

HTLV-1 integration into transcriptionally active genomic regions is associated with proviral expression and with HAM/TSP. [PDF]

PLoS Pathogens, 2008
Human T-lymphotropic virus type 1 (HTLV-1) causes leukaemia or chronic inflammatory disease in approximately 5% of infected hosts. The level of proviral expression of HTLV-1 differs significantly among infected people, even at the same proviral load ...
Kiran N Meekings, Jeremy Leipzig, Frederic D Bushman, Graham P Taylor, Charles R M Bangham   +4 more
doaj   +1 more source

Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients. [PDF]

PLoS ONE, 2013
Toll-like receptor (TLR) agonists can reactivate HIV from latently infected cells in vitro. We aimed to investigate the TLR-9 agonist, CPG 7909's in vivo effect on the proviral HIV reservoir and HIV-specific immunity.
Anni A Winckelmann, Lærke V Munk-Petersen, Thomas A Rasmussen, Jesper Melchjorsen, Thomas J Hjelholt, David Montefiori, Lars Østergaard, Ole S Søgaard, Martin Tolstrup   +8 more
doaj   +1 more source

HTLV-1 Proliferation after CD8+ Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques

Microbiology Spectrum, 2023
Human T-cell leukemia virus type 1 (HTLV-1) induces chronic asymptomatic latent infection with a substantial proviral load but without significant viral replication in vivo.
Midori Nakamura-Hoshi, Takushi Nomura, Masako Nishizawa, Trang Thi Thu Hau, Hiroyuki Yamamoto, Midori Okazaki, Hiroshi Ishii, Kenzo Yonemitsu, Yuriko Suzaki, Yasushi Ami, Tetsuro Matano   +10 more
doaj   +1 more source

Dynamics of perinatal bovine leukemia virus infection [PDF]

, 2014
BACKGROUND: Bovine leukemia virus (BLV) is highly endemic in many countries, including Argentina. As prevention of the spread from infected animals is of primary importance in breaking the cycle of BLV transmission, it is important to know the ...
Alvarez, Irene, Gutiérrez, Gerónimo, Merlini, Ramiro, Rondelli, Flavia, Trono, Karina Gabriela   +4 more
core   +3 more sources

Single nucleotide polymorphisms in the bovine MHC region of Japanese Black cattle are associated with bovine leukemia virus proviral load

Retrovirology, 2017
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, a malignant B cell lymphoma that has spread worldwide and causes serious problems for the cattle industry.
Shin-nosuke Takeshima, Shinji Sasaki, Polat Meripet, Yoshikazu Sugimoto, Yoko Aida   +4 more
doaj   +1 more source

High prevalence of bronchiectasis is linked to HTLV-1-associated inflammatory disease. [PDF]

, 2015
BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL).
A Gessain, A Gessain, AH Smith, AM Vine, CR Bangham, D Weycker, E Gotuzzo, EL Murphy, F Okada, Graham P Taylor, H Kawai, H Merle, H Nakamura, IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, J Crofton, JR Orland, K Nishioka, L Einsiedel, L Einsiedel, L Einsiedel, L LaGrenade, M Nagai, M Nakagawa, M Osame, M Sugimoto, M Sugimoto, MA Demontis, MG Flynn, OS Morgan, PJ McShane, S Mita, S Mori, Shohreh Honarbakhsh, T Arakaki, T Kondo, T Matsuda, T Yamashiro, W Matsuyama   +37 more
core   +1 more source

HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy [PDF]

, 1999
The risk of disease associated with persistent virus infections such as HIV-I, hepatitis B and C, and human T-lymphotropic virus-I (HTLV-I) is strongly determined by the virus load.
Bangham, C.R.M., Bunce, M., Hall, S.E., Izumo, S., Jeffery, K.J.M., Kodama, D., Lloyd, A.L., Matsumoto, W., Nagai, M., Nowak, M.A., Ogg, G.S., Osame, M., Procter, J., Taylor, G.P., Usuku, K., Weber, J.N., Welsh, K.I.   +16 more
core   +2 more sources

Genetic diversity in the env V1-V2 region of proviral quasispecies from long-term controller MHC-typed cynomolgus macaques infected with SHIVSF162P4cy [PDF]

, 2018
Intra-host evolution of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) has been shown by viral RNA analysis in subjects who naturally suppress plasma viremia to low levels, known as controllers.
Borsetti, Alessandra, Capone, Alessia, Cella, Eleonora, Ciccozzi, Massimo, Ensoli, Barbara, Farcomeni, Stefania, Ferrantelli, Flavia, Lo Presti, Alessandra, Maggiorella, Maria T, Mee, Edward T, Rose, Nicola J, Sernicola, Leonardo   +11 more
core   +1 more source