Results 31 to 40 of about 99,225 (351)

The Na+/H+ Exchanger 3 in the Intestines and the Proximal Tubule of the Kidney: Localization, Physiological Function, and Key Roles in Angiotensin II-Induced Hypertension

Frontiers in Physiology, 2022
The sodium (Na+)/hydrogen (H+) exchanger 3 (NHE3) is one of the most important Na+/H+ antiporters in the small intestines of the gastrointestinal tract and the proximal tubules of the kidney.
Sarah M. Nwia, Sarah M. Nwia, Xiao Chun Li, Xiao Chun Li, Ana Paula de Oliveira Leite, Ana Paula de Oliveira Leite, Rumana Hassan, Rumana Hassan, Jia Long Zhuo, Jia Long Zhuo   +9 more
doaj   +1 more source

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism

Scientific Reports, 2018
Fibroblast growth factor 23 (FGF23) plays critical roles in phosphate handling and vitamin D metabolism in the kidney. However, the effector cells of FGF23 in the kidney remain unclear.
Ai Takeshita, Kazuki Kawakami, Kenryo Furushima, Masayasu Miyajima, Kazushige Sakaguchi   +4 more
doaj   +1 more source

Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly [PDF]

, 2011
During mitosis, the nuclear envelope merges with the endoplasmic reticulum (ER), and nuclear pore complexes are disassembled. In a current model for reassembly after mitosis, the nuclear envelope forms by a reshaping of ER tubules.
Anderson, Anderson, Anderson, Antonin, Baumann, Belgareh, Bodoor, Burke, Chaudhary, Comings, Crisp, Cronshaw, Doucet, Drin, Dultz, Dultz, D’Angelo, Ehrlich, Ellenberg, Ferko, Franz, Gillespie, Goldberg, Haraguchi, Haraguchi, Haraguchi, Harel, Hetzer, Kiseleva, Kremer, Lei Lu, Lu, Macaulay, Mark S. Ladinsky, Mastronarde, Mastronarde, Maul, Patel, Puhka, Rabut, Rasala, Rasala, Rotem, Sheehan, Tomas Kirchhausen, Voeltz, Walther, Yang, Zuccolo   +48 more
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Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]

, 2017
Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola, E. O. Dada, I. B. Osho, O. O. Ogundolie   +3 more
core   +1 more source

Changes in renal WT-1 expression preceding hypertension development [PDF]

, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica, Calvo, Juan Pablo, Casarotto, Mariana, Cuello Carrión, Fernando Darío, Ferder, León, Fornes, Miguel Walter, García, Isabel Mercedes, Manucha, Walter Ariel Fernando, Mazzei, Luciana Jorgelina   +8 more
core   +2 more sources

The Antidiabetic Agent Sodium Tungstate Induces Abnormal Glycogen Accumulation in Renal Proximal Tubules from Diabetic IRS2-Knockout Mice

Journal of Diabetes Research, 2018
The kidney is an insulin-sensitive organ involved in glucose homeostasis. One major effect of insulin is to induce glycogen storage in the liver and muscle.
Romina Bertinat, Francisco Westermeier, Pamela Silva, Rodrigo Gatica, Joana Moitinho Oliveira, Francisco Nualart, Ramón Gomis, Alejandro J. Yáñez   +7 more
doaj   +1 more source

Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis [PDF]

, 2017
Removal of renal mass stimulates anatomical and functional adaptations in the surviving nephrons, including elevations in single-nephron glomerular filtration rate (SNGFR) and tubular hypertrophy. A goal of this study is to assess the extent to which the
Edwards, Aurelie, Layton, Anita T., Vallon, Volker   +2 more
core   +1 more source

Canine liver transplantation under nva cyclosporine versus cyclosporine [PDF]

, 1986
The immunosuppressive qualities and other features of a new cyclosporine (CsA) analogue, Nva 2-cyclosporine (Nva 2-CsA) were examined using canine orthotopic liver allografts.
DeWolf, A, Kam, I, Lynch, S, Porter, KA, Starzl, TE, Todo, S, Venkataramanan, R   +6 more
core   +1 more source

Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis [PDF]

, 2015
Spermatogenesis is a highly regulated process that involves both mitotic and meiotic divisions, as well as cellular differentiation to yield mature spermatozoa from undifferentiated germinal stem cells.
Cattaneo, Elizabeth Renee, Coleman, Rosalind A., Garcia Fabiani, Maria Belen, Gonzalez-Baró, Lacunza, Ezequiel, Montanaro, Mauro Aldo, Pellon Maison, Magali   +6 more
core   +2 more sources

Proximal Convoluted Tubules as the Primary Target of Renal Histopathological Injury by Ingestion of Pesticide-Residue-Laden Fruits and Vegetables

Journal of Islamic International Medical College, 2021
Objective: To determine the potential adverse renal histopathological effects on the proximal convoluted tubules in male, Wistar rats due to ingestion of subchronic dose of triazophos. Study Design: Randomized controlled trial.
Lubna Shahper , Shagufta Nasreen , Muhammad Qasim Muneer , Nazia Ayyub , Sadia Hassan
doaj