Results 111 to 120 of about 14,311 (225)

Vaccination of sows against type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) before artificial insemination protects against type 2 PRRSV challenge but does not protect against type 1 PRRSV challenge in late gestation [PDF]

, 2014
International audienceThe objective of the present study was to determine the effects of the commercially available type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)-based modified live vaccine against type 1 and type 2 PRRSV challenge ...
Seo, Hwi Won, Changhoon Park, Kiwon Han, Han, Kiwon, Chae, Chanhee, Park, Changhoon, Chanhee Chae, Hwi Seo, Hwi Won Seo   +8 more
core   +1 more source

Establishment of Systems to Enable Isolation of Porcine Monoclonal Antibodies Broadly Neutralizing the Porcine Reproductive and Respiratory Syndrome Virus

Frontiers in Immunology, 2019
The rapid evolution of porcine reproductive and respiratory syndrome viruses (PRRSV) poses a major challenge to effective disease control since available vaccines show variable efficacy against divergent strains.
David Goldeck, Dana M. Perry, Dana M. Perry, Jack W. P. Hayes, Jack W. P. Hayes, Luke P. M. Johnson, Luke P. M. Johnson, Jordan E. Young, Parimal Roychoudhury, Parimal Roychoudhury, Elle L. McLuskey, Elle L. McLuskey, Katy Moffat, Arjen Q. Bakker, Mark J. Kwakkenbos, Jean-Pierre Frossard, Raymond R. R. Rowland, Michael P. Murtaugh, Simon P. Graham, Simon P. Graham   +19 more
doaj   +1 more source

Epitope mapping and characterization of a novel Nsp10-specific monoclonal antibody that differentiates genotype 2 PRRSV from genotype 1 PRRSV [PDF]

, 2017
Background Porcine reproductive and respiratory syndrome virus (PRRSV), the causative agent of PRRS, has two distinct and highly diverse genotypes (genotype 1 and genotype 2) in the field.
Xin Guo, Xuexia Wen, Hanchun Yang, Zhibang Zhang, Xinna Ge, Lei Zhou, Jianguo Dong   +6 more
core   +1 more source

A centralised immunogen approach to develop a more broadly protective modified live porcine reproductive and respiratory syndrome virus 1 vaccine candidate

npj Vaccines
More efficacious vaccines are required to improve control of porcine reproductive and respiratory syndrome viruses (PRRSV). One strategy that has shown promise is the use of centralized antigens, generated from consensus sequence data. Here, we evaluated
Rory C. F. de Brito, Yashar Sadigh, Joseph Bowman, Stephanie Clive, Ben Jackson, Miriam Pedrera, Fraser Crofts, Matthieu Bernard, Fabian Z. X. Lean, Alejandro Núñez, Julian Seago, Jean-Pierre Frossard, Simon P. Graham   +12 more
doaj   +1 more source

Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression

Virulence
Porcine reproductive and respiratory syndrome virus (PRRSV) has a disastrous impact on the global swine industry. Even though PRRS commercial vaccines can provide homologous protection, broadly effective anti-PRRSV strategies are still in urgent need ...
Ming Qiu, Xinshuai Li, Shuai Li, Shubin Li, Ningjun Xie, Zhe Sun, Hong Lin, Jianzhong Zhu, Kegong Tian, Nanhua Chen   +9 more
doaj   +1 more source

T Cell Response to Infection by the Porcine Reproductive and Respiratory Syndrome Virus [PDF]

, 2006
The purpose of the research has been to characterize the response of naïve or virus-specific swine T lymphocytes from different lymphoid compartments to Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Peripheral blood mononuclear cells (
Chen, Hsin-Ying
core  

A chimeric strain of porcine reproductive and respiratory syndrome virus 2 derived from HP-PRRSV and NADC30-like PRRSV confers cross-protection against both strains

Veterinary Research
Porcine reproductive and respiratory syndrome (PRRS) is one of the most significant swine viral infectious diseases worldwide. Vaccination is a key strategy for the control and prevention of PRRS.
Yang Li, Yumiao Wang, Xiuxiu Pei, Shao Chen, Yang Jing, Yongshuai Wu, Zhiqian Ma, Zhiwei Li, Zifang Zheng, Yingtong Feng, Lele Xu, Xiao Liu, Xuyang Guo, Haixue Zheng, Shuqi Xiao   +14 more
doaj   +1 more source

Etiological Detection, Isolation, and Pathogenicity of Porcine Reproductive and Respiratory Syndrome Virus in China

Veterinary Sciences
Due to its high genomic variability, the epidemiological landscape of porcine reproductive and respiratory syndrome virus (PRRSV) has become increasingly complex in recent years.
Yingbin Du, Jingyi Chen, Tianze Ren, Chunying Xie, Yiye Zhang, Liurong Fang, Yanrong Zhou   +6 more
doaj   +1 more source

Single-cell RNA sequencing analysis reveals a novel porcine alveolar macrophage subtype with high SLAMF7 expression promoting PRRSV infection

Virulence
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major and highly contagious swine pathogen that severely impacts the global pork industry.
Ankang Hu, Yao Guo, Yusi Zhou, Piao Chen, Yuhua Zhu, Tingjun Liu, Lianlian Wu, Dandan Qiao, Zhutao Huang, Yang Chen, Xufeng Han, Jing Liu, Quangang Chen   +12 more
doaj   +1 more source

Deciphering immune features and cellular heterogeneity in PRRSV infection via single-cell RNA sequencing

Journal of Virology
Porcine reproductive and respiratory syndrome virus (PRRSV), a major immunosuppressive pathogen, inflicts substantial economic losses on the global swine industry.
Jianda Li, Yue Liang, Yuyu Zhang, Yulin Xu, Fei Liu, Luogang Ding, Yu Wang, Zhihao Zhang, Zhi Chen, Wenbo Sun, Jiang Yu, Jiaqiang Wu   +11 more
doaj   +1 more source