Results 101 to 110 of about 14,311 (225)

The GP2a 91/97/98 amino acid substitutions play critical roles in determining PRRSV tropism and infectivity but do not affect immune responses

Journal of Virology
Porcine reproductive and respiratory syndrome virus (PRRSV) isolates share a restricted cellular tropism. Marc-145 cells derived from African green monkey are one of the few cell lines supporting PRRSV propagation in vitro and are commonly used for PRRS ...
Ming Qiu, Shuai Li, Shubin Li, Zhe Sun, Hong Lin, Shuai Yang, Meng Cui, Yuejia Qiu, Wenhao Qi, Xiuling Yu, Shaobin Shang, Kegong Tian, François Meurens, Jianzhong Zhu, Nanhua Chen   +14 more
doaj   +1 more source

Protein nanoparticles assemble in plants, display antigenic viral peptides, and produce an epitope‐specific immune response

The FEBS Journal, Volume 293, Issue 7, Page 1891-1907, April 2026.
Current methods to control porcine reproductive and respiratory syndrome, a disease affecting pigs, are insufficient and a safer, more effective vaccine is needed. This study describes the design and plant production of a self‐assembling protein nanoparticle vaccine candidate against this disease.
Jordan T. VanderBurgt, Richard Strasser, Hong Zhu, Angelo Kaldis, Christopher P. Garnham, Rima Menassa   +5 more
wiley   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Diverse Scaffolds Facilitate NLRP3 Clustering and Inflammasome Formation in Response to Perturbations in Cell Homeostasis

BioEssays, Volume 48, Issue 3, March 2026.
NLRP3, a cytosolic innate immune sensor, responds to diverse activators that perturb cellular homeostasis. These disturbances generate molecular scaffolds that, through binding partners such as nucleic acids, lipids, and proteins, recruit and concentrate NLRP3. Scaffold‐mediated NLRP3 clustering promotes NLRP3 inflammasome assembly.
Elvira Boršić‐Mlinarič, Iva Hafner‐Bratkovič   +1 more
wiley   +1 more source

The impact of respiratory disease on production in the pig industry in Great Britain [PDF]

This thesis presents research on the epidemiology of respiratory diseases in pig herds in GB and their impact on pig morbidity and mortality. The role of management, characteristics of the herd, presence of multiple pathogens and control and ...
Evans, Charlotte Marie
core  

Development of a novel duplex crystal digital PCR for the detection of PRRSV-1 and PRRSV-2. [PDF]

Front Cell Infect Microbiol
Background Porcine reproductive and respiratory syndrome (PRRS) is a widely prevalent disease of reproductive failure of pregnant pigs and respiratory syndromes in pigs of different ages, especially in piglets.
Shi Y, He J, Shi K, Yin Y, Long F, Feng S, Wei Z.   +6 more
europepmc   +3 more sources

Mitochondrial dysfunction in PRRSV-2-infected macrophages [PDF]

International audienceIntroduction Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most economically devastating viruses for the global swine industry.
Liu, Hsiao-Ching, Vu Manh, Thien-Phong, Byrne, John, Frias-De-Diego, Alba, Hicks, Julie, Williams, Abigail, Crisci, Elisa, Sirisereewan, Chaitawat   +7 more
core   +1 more source

Relationships of CD163 and CD169 positive cell numbers in the endometrium and fetal placenta with type 2 PRRSV RNA concentration in fetal thymus [PDF]

, 2016
Several routes of porcine reproductive and respiratory virus PRRSV transmission across the porcine diffuse epitheliochorial placentation have been proposed, but none have been proven.
Detmer, Susan E., Harding, John C. S., Novakovic, Predrag, Ladning, Andrea, Al-Dissi, Ahmad N., MacPhee, Daniel J.   +5 more
core   +2 more sources

Xanthohumol inhibits PRRSV proliferation and alleviates oxidative stress induced by PRRSV via the Nrf2–HMOX1 axis [PDF]

, 2019
International audiencePorcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent and endemic swine pathogen that causes significant economic losses in the global swine industry.
Nauwynck, Hans, Bai, Juan, Song, Zhongbao, Zhao, Yongxiang, Jiang, Ping, Liu, Xuewei   +5 more
core   +2 more sources

Epidemiological surveillance and economic impact analysis of different porcine reproductive and respiratory syndrome virus infection statuses in 23 breeding pig farms in Hubei, China

Animal Diseases
Porcine reproductive and respiratory syndrome virus (PRRSV) has emerged as a significant threat to the pig farming industry worldwide, resulting in considerable economic losses. However, few reports detail its economic impact on the pig farming sector. A
Huifeng Zhao, Jingwei Zhou, Min Zhang, Xiutao Yang, Zhaofang Xi, Qingxia Gao, Rui Fang, Pengfei Zhao, Junlong Zhao   +8 more
doaj   +1 more source