Results 81 to 90 of about 15,921 (224)

PRRSV-2 infection-induced PLIN2 degradation requires RAB18 and lysosome.

open access: yes
(A) Sgcontrol and sgRAB18 MARC-145 cells were infected with LP-PRRSV-2 (MOI = 10) for 0–36 h. PLIN2, RAB18, PRRSV-2-N and ATCB were analyzed by immunoblot analysis.
Guo-Yu Yang (1728175)   +9 more
core   +1 more source

PRRSVSD23983-infected and clinically recovered gilt-2 had PRRSV-specific cytotoxic T-cells.

open access: yes, 2018
Cytotoxic T-lymphocyte responses were measured by the percentage of PRRSV-infected MDM (TFL4+) that received the lethal death signal (PS+) at 0, 3 and 24 hours post-PRRSV infection. The phenotypes of cytotoxic T-cells were determined by the percentage of
Jieun Yu (5725070)   +8 more
core   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

open access: yesAdvanced Science, Volume 13, Issue 45, 13 August 2026.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan   +7 more
wiley   +1 more source

Diagnosis and characteristics of simultaneous PRRSV-1 and PRRSV-2 infection

open access: yes, 2023
Virus reproduktivnog i respiratornog sindroma svinja (PRRSV) je prvi put u Srbiji otkriven 2001. godine. PRRSV pripada familiji Arteriviridae i razvrstava se u dva genotipa, genotip PRRSV-1 i PRRSV-2.
Veljović, Ljubiša   +4 more
core   +1 more source

Analysis of PRRSV-ADE infection in poFcγRII bearing cell lines.

open access: yes, 2013
PRRSV BJ-4 virions with whole or F(ab')2 fragment of anti-PRRSV IgG were added to either Marc-poFcγRII cell lines and macrophages or Marc-145 cells.
Bo Wan (212083)   +10 more
core   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection Against Pseudorabies Virus

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun   +11 more
wiley   +1 more source

Follow-up of PRRSv-vaccinated piglets born from PRRSv-vaccinated, ELISA-seropositive and ELISA-seronegative sows

open access: yes, 2023
Vaccination against the porcine reproductive and respiratory syndrome virus (PRRSv) is widely used to prevent production losses in the swine industry. In this study, piglets born from both PRRSv-vaccinated ELISA-seropositive sows (E+ piglets) and PRRSv ...
Tignon, Marylene   +3 more
core   +2 more sources

Epidemiological surveillance and economic impact analysis of different porcine reproductive and respiratory syndrome virus infection statuses in 23 breeding pig farms in Hubei, China

open access: yesAnimal Diseases
Porcine reproductive and respiratory syndrome virus (PRRSV) has emerged as a significant threat to the pig farming industry worldwide, resulting in considerable economic losses. However, few reports detail its economic impact on the pig farming sector. A
Huifeng Zhao   +8 more
doaj   +1 more source

Establishment of CD163-truncated gene-edited pigs and evaluation of their anti-PRRSV ability

open access: yesHuanan Nongye Daxue xuebao
ObjectiveThis study aims to generate Large White pigs with a five-amino acid deletion (Δ525-529, AHFGE) in the SRCR5 domain of CD163 using CRISPR/Cas9 gene editing combined with somatic cell nuclear transfer, and evaluate their resistance to porcine ...
Jiayong TAN   +5 more
doaj   +1 more source

A Rapid, Field‐Deployable Diagnostic Platform for Getah Virus Based on RT‐RAA and CRISPR EsCas13d

open access: yesMicrobial Biotechnology, Volume 19, Issue 8, August 2026.
This study developed a rapid, one‐step, visual detection platform termed ROSVD by integrating RT‐RAA with CRISPR–EsCas13d, enabling simplified sample preparation, high‐sensitivity, on‐site detection of GETV within 30 min without the need for sophisticated equipment.
Liu Baoling   +5 more
wiley   +1 more source

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