Results 81 to 90 of about 14,311 (225)

The 2b protein as a minor structural component of PRRSV [PDF]

Virus Research, 2005
Porcine reproductive and respiratory syndrome virus (PRRSV) ORF2 contains an internal ORF that codes for a small non-glycosylated protein known as 2b. Previous work had identified the presence of a 10kDa 2b protein in virus-infected cells and the induction of an anti-2b response in PRRSV-infected pigs, as well as a possible association of 2b with the ...
Wu, Wai-Hong, Fang, Ying, Rowland, Raymond R.R., Lawson, Steven R., Christopher-Hennings, Jane, Yoon, Kyoung-Jin, Nelson, Eric A.   +6 more
openaire   +2 more sources

PRRSV titration results. [PDF]

PRRSV MN 1-8-4 and PRRSV 1-4-4 L1C Variant titration results per surface, contact time and temperature. (PDF)
Gustavo S. Silva (8286627), Mckenna Brinning (17816853), Isadora Machado (17816841), Vivian Flores (17816868), Onyekachukwu Osemeke (17816847), Mafalda Mil-Homens (16810497), Daniel Moraes (17816850), Swaminathan Jayaraman (14562014), Ethan Aljets (17816838), Ana Paula Poeta Silva (17816856), Mallory Wilhelm (17816865), Jianqiang Zhang (613834), Madison Durflinger (17816862), Jolie Frenier (17816871), Derald Holtkamp (4635799), Daniel Linhares (17816874), Lauren Tidgren (17816859), Rodrigo C. Paiva (16810485), Guilherme Cezar (17816844)   +18 more
core   +1 more source

Two Commercial Type 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)-Modified Live Vaccines Reduce Seminal Shedding of Type 1 PRRSV but not Type 2 PRRSV in Infected Boars [PDF]

, 2017
The objective of this study was to compare the effects of two commercial type 1 porcine reproductive and respiratory syndrome virus (PRRSV)-modified live vaccines on type 1 and type 2 PRRSV shedding in the semen of experimentally infected boars.
Kang, I., Park, C., Jeong, J., Park, S. -J., Chae, C., Kim, T., Choi, K.   +6 more
core   +1 more source

EGCG Restricts PRRSV Proliferation by Disturbing Lipid Metabolism

Microbiology Spectrum, 2022
Porcine reproductive and respiratory syndrome virus (PRRSV) infection leads to late-term reproductive failure and respiratory illness that affect the global swine industry.
Peng-Wei Yu, Peng-Fei Fu, Lei Zeng, Yan-Li Qi, Xiu-Qing Li, Qi Wang, Guo-Yu Yang, Hua-Wei Li, Jiang Wang, Bei-Bei Chu, Meng-Di Wang   +10 more
doaj   +1 more source

Discovery of Novel Viruses and Common Contaminants From Unmapped DNA and RNA in Pigs and Chickens Under Different Housing Conditions

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Unmapped sequencing reads in livestock often contain valuable information about pathogens but are typically discarded. We analyzed blood‐derived DNA and RNA from chickens and pigs kept under high‐ and low‐biosecurity conditions, focusing on unmapped reads.
Martijn F. L. Derks, Bert Dibbits, Richard P. M. A. Crooijmans, Kim Lensing   +3 more
wiley   +1 more source

PRRSV Non-Structural Proteins Orchestrate Porcine E3 Ubiquitin Ligase RNF122 to Promote PRRSV Proliferation [PDF]

, 2022
Ubiquitination plays a major role in immune regulation after viral infection. An alternatively spliced porcine E3 ubiquitin ligase RNF122 promoted PRRSV infection and upregulated in PRRSV-infected PAM cells was identified.
Ruiqi Sun, Jinhai Huang, Yanyu Guo, Jun Han, Lei Zhang, Lilin Zhang, Ruiqiao Li, Jingxuan Shi, Xiaoyang Li, Zheng Tan   +9 more
core   +1 more source

A broadly neutralizing monoclonal antibody induces broad protection against heterogeneous PRRSV strains in piglets

Veterinary Research, 2021
Neutralizing antibodies (NAbs) have attracted attention as tools for achieving PRRSV control and prevention, but viral antigenic variation undermines the abilities of NAbs elicited by attenuated PRRSV vaccines to confer full protection against ...
Zhigang Zhang, Tianshu Zhai, Mingshuo Li, Kun Zhang, Jingrui Li, Xu Zheng, Chaonan Tian, Rui Chen, Jianhui Dong, En-Min Zhou, Yuchen Nan, Chunyan Wu   +11 more
doaj   +1 more source

Nanopore direct RNA sequencing and the epitranscriptome: Advances in mapping native RNA landscapes

iMeta, Volume 5, Issue 3, June 2026.
Nanopore direct RNA sequencing advances transcriptomics by capturing full‐length transcripts and multiple RNA modifications; this review details its principles, workflows, tools, applications, challenges, and future research potential. Abstract Nanopore direct RNA sequencing (DRS) has transformed transcriptomics by enabling single‐molecule, long‐read ...
Tianyuan Zhang, Jia Li, Chao Tang, You Wu, Hao Wu, Xi‐Tong Zhu, Ziyang Luo, Hang Qin, Lishan Ding, Yu Zeng, Shiou Yih Lee, Xiaotao Shen, Shiwen Gao, Zhaoyang Tian, Qian Tang, Mian Li, Muhammad Tahir Ul Qamar, Yang Dong, Komivi Dossa, Yaxuan Zhang, Hu Chen, Sanqi An, Xiang Yu, Lu Chen, Dingjie Wang, Shengli Li, Ling‐Ling Chen, Yanqiang Li   +27 more
wiley   +1 more source

PRRSV_SD23983-infected and clinically recovered gilt-2 had PRRSV-specific cytotoxic T-cells. [PDF]

, 2018
Cytotoxic T-lymphocyte responses were measured by the percentage of PRRSV-infected MDM (TFL4+) that received the lethal death signal (PS+) at 0, 3 and 24 hours post-PRRSV infection. The phenotypes of cytotoxic T-cells were determined by the percentage of
Jieun Yu (5725070), Sang-Ho Cha (1527031), Joanna Rzepka (3744965), Amanda L. Grimm (3308100), Dharani Ajithdoss (5725067), Grace Chung (2268085), Chak-Sum Ho (668078), Chungwon J. Chung (3308094), William C. Davis (464877)   +8 more
core   +1 more source

Porcine Reproductive and Respiratory Syndrome Virus Antagonizes PCSK9’s Antiviral Effect via Nsp11 Endoribonuclease Activity

Viruses, 2020
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important pathogens in the swine industry worldwide. Our previous study had indicated that proprotein convertase subtilisin/kexin type 9 (PCSK9) was a responsive gene in ...
Yujiao Zhang, Fei Gao, Liwei Li, Kuan Zhao, Shan Jiang, Yifeng Jiang, Lingxue Yu, Yanjun Zhou, Changlong Liu, Guangzhi Tong   +9 more
doaj   +1 more source