Results 81 to 90 of about 15,921 (224)
PRRSV-2 infection-induced PLIN2 degradation requires RAB18 and lysosome.
(A) Sgcontrol and sgRAB18 MARC-145 cells were infected with LP-PRRSV-2 (MOI = 10) for 0–36 h. PLIN2, RAB18, PRRSV-2-N and ATCB were analyzed by immunoblot analysis.
Guo-Yu Yang (1728175) +9 more
core +1 more source
PRRSVSD23983-infected and clinically recovered gilt-2 had PRRSV-specific cytotoxic T-cells.
Cytotoxic T-lymphocyte responses were measured by the percentage of PRRSV-infected MDM (TFL4+) that received the lethal death signal (PS+) at 0, 3 and 24 hours post-PRRSV infection. The phenotypes of cytotoxic T-cells were determined by the percentage of
Jieun Yu (5725070) +8 more
core +1 more source
Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan +7 more
wiley +1 more source
Diagnosis and characteristics of simultaneous PRRSV-1 and PRRSV-2 infection
Virus reproduktivnog i respiratornog sindroma svinja (PRRSV) je prvi put u Srbiji otkriven 2001. godine. PRRSV pripada familiji Arteriviridae i razvrstava se u dva genotipa, genotip PRRSV-1 i PRRSV-2.
Veljović, Ljubiša +4 more
core +1 more source
Analysis of PRRSV-ADE infection in poFcγRII bearing cell lines.
PRRSV BJ-4 virions with whole or F(ab')2 fragment of anti-PRRSV IgG were added to either Marc-poFcγRII cell lines and macrophages or Marc-145 cells.
Bo Wan (212083) +10 more
core +1 more source
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun +11 more
wiley +1 more source
Vaccination against the porcine reproductive and respiratory syndrome virus (PRRSv) is widely used to prevent production losses in the swine industry. In this study, piglets born from both PRRSv-vaccinated ELISA-seropositive sows (E+ piglets) and PRRSv ...
Tignon, Marylene +3 more
core +2 more sources
Porcine reproductive and respiratory syndrome virus (PRRSV) has emerged as a significant threat to the pig farming industry worldwide, resulting in considerable economic losses. However, few reports detail its economic impact on the pig farming sector. A
Huifeng Zhao +8 more
doaj +1 more source
Establishment of CD163-truncated gene-edited pigs and evaluation of their anti-PRRSV ability
ObjectiveThis study aims to generate Large White pigs with a five-amino acid deletion (Δ525-529, AHFGE) in the SRCR5 domain of CD163 using CRISPR/Cas9 gene editing combined with somatic cell nuclear transfer, and evaluate their resistance to porcine ...
Jiayong TAN +5 more
doaj +1 more source
A Rapid, Field‐Deployable Diagnostic Platform for Getah Virus Based on RT‐RAA and CRISPR EsCas13d
This study developed a rapid, one‐step, visual detection platform termed ROSVD by integrating RT‐RAA with CRISPR–EsCas13d, enabling simplified sample preparation, high‐sensitivity, on‐site detection of GETV within 30 min without the need for sophisticated equipment.
Liu Baoling +5 more
wiley +1 more source

