Results 61 to 70 of about 15,307 (229)
Veterinary Research, 2021 Neutralizing antibodies (NAbs) have attracted attention as tools for achieving PRRSV control and prevention, but viral antigenic variation undermines the abilities of NAbs elicited by attenuated PRRSV vaccines to confer full protection against ...
Zhigang Zhang +11 more
doaj +1 more source
VIEW, EarlyView.This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song +14 more
wiley +1 more source
PRRSv-specific IFNγ response before and after challenge.
, 2019 Spot forming units of 1x106 porcine PBMCs stimulated with RPMI medium (circles) or PRRS virus (squares, MOI of 1.0) were determined before PRRS virus challenge (a) and 10 days after PRRS virus challenge (b) by IFNγ ELISpot. c) Comparison of PRRSv (MOI 1)
Christian Kraft (269160) +6 more
core +1 more source
Let-7 family inhibits PRRSV-2 replication and directly target PRRSV-2 genomic RNA.
, 2022 Marc-145 cells were transfected with let-7 mimics/inhibitor, and then infected with PRRSV-2. The cells were collected at 9 hpi (9h) and 36 hpi (36h).
Huijuan Li (626298) +9 more
core +1 more source
Evaluation of PRRSV vaccine efficacy following infection with PRRSV 1-7-4
Journal of Swine Health and Production, 2021 Our objective was to evaluate whether porcine reproductive and respiratory syndrome virus (PRRSV) vaccination improved mortality and morbidity following experimental infection with a PRRSV restriction fragment length polymorphism 1-7-4. Results indicated that mortality and morbidity were significantly lower for vaccinated pigs as compared to ...
Erin Little +7 more
openaire +1 more source
Glycyrrhiza polysaccharides inhibits PRRSV replication
Virology Journal, 2023 AbstractGlycyrrhiza polysaccharide (GCP) is a natural plant active polysaccharide extracted from traditional Chinese medicine licorice. In this research, we studied the antiviral activity of glycyrrhiza polysaccharide against porcine reproductive and respiratory syndrome virus (PRRSV), a virus of the Arteriviridae family, with a high rate of variation ...
Youbing Yang +6 more
openaire +3 more sources
Viruses, 2020 Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important pathogens in the swine industry worldwide. Our previous study had indicated that proprotein convertase subtilisin/kexin type 9 (PCSK9) was a responsive gene in ...
Yujiao Zhang +9 more
doaj +1 more source
Microbiology Spectrum, 2022 Porcine reproductive and respiratory syndrome virus (PRRSV), a porcine arterivirus, causes severe financial losses to global swine industry. Despite much research, the molecular mechanisms of PRRSV infection remains to be fully elucidated. In the current
Lei Wang +6 more
doaj +1 more source
Advanced Science, Volume 13, Issue 50, 7 September 2026.A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen +5 more
wiley +1 more source
EGCG Restricts PRRSV Proliferation by Disturbing Lipid Metabolism
Microbiology Spectrum, 2022 Porcine reproductive and respiratory syndrome virus (PRRSV) infection leads to late-term reproductive failure and respiratory illness that affect the global swine industry.
Peng-Wei Yu +10 more
doaj +1 more source