Results 51 to 60 of about 15,307 (229)

PRRSv-specific antibody response before and after challenge.

open access: yes, 2019
a) PRRSv-specific IgG and (b) IgA response were assessed by PRRSv-specific ELISA at the indicated time points. Each symbol represents the calculated average of one animal.
Christian Kraft (269160)   +6 more
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

Identification of MYH9 Key Domain Involved in the Entry of PRRSV Into Permissive Cells

open access: yesFrontiers in Microbiology, 2022
Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen that causes huge losses economically to the pig industry worldwide. Previous research suggested that receptor dependence is necessary for PRRSV infection. MYH9 and CD163
Liangliang Li   +6 more
doaj   +1 more source

MiniSdd7‐Derived Cytosine Base Editor Promotes Efficient Multiplex Gene Knockout in Porcine Primary Fibroblasts

open access: yesAnimal Research and One Health, EarlyView.
The miniSdd7‐BE4max‐SpG system enables highly efficient multiplex C‐to‐T base editing of APN, CD163, and MSTN in porcine fibroblasts, providing a robust platform for future development of multiplex gene‐edited livestock. ABSTRACT Efficient multiplex genome editing is essential for improving complex traits in livestock that are governed by multiple ...
Shaoshuai Wang   +4 more
wiley   +1 more source

PRRSV-specific antibody titers (S/P ratios) by ELISA in the time course of the different groups.

open access: yes, 2018
S/P ratio for non-vaccinated gilts (group 1), gilts that received intradermal PRRSV vaccination into the neck (group 2) and sows that received intradermal PRRSV vaccination into perianal region (group 3) are shown. Mean S/P ratios for the three different
Armin Saalmüller (318023)   +10 more
core   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

open access: yesAnimal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Follow-up of PRRSv-vaccinated piglets born from PRRSv-vaccinated, ELISA-seropositive and ELISA-seronegative sows

open access: yes, 2023
Vaccination against the porcine reproductive and respiratory syndrome virus (PRRSv) is widely used to prevent production losses in the swine industry. In this study, piglets born from both PRRSv-vaccinated ELISA-seropositive sows (E+ piglets) and PRRSv ...
Tignon, Marylene   +3 more
core   +2 more sources

Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt   +3 more
wiley   +1 more source

Type 2 PRRSV-infected PGE demonstrated high cytopathic effects (CPE), PRRSV-positive cells and viral titers.

open access: yes, 2023
PGE monolayers infected with mock, type 1, or type 2 at 105 TCID50/mL were observed for CPE, and PRRSV positive cells were investigated by immunocytochemistry using antibody against PRRSV envelop glycoprotein GP5.
Sutthasinee Poonyachoti (15361276)   +5 more
core   +1 more source

Reframing Technology and Ethics in Corneal Xenotransplantation: A Scoping Review of Standards and Safety in Ophthalmology

open access: yesHealth Care Science, EarlyView.
Bringing attention to the moral dilemmas raised by xenotransplantation and the continuous creation of standardized frameworks for donor technology and biosafety risk management, with a focus on striking a balance between patient safety, medical innovation, and ethical obligation.
Sankhajyoti Saha   +2 more
wiley   +1 more source

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