Results 31 to 40 of about 10,101 (182)

A Novel Motif in the 3′-UTR of PRRSV-2 Is Critical for Viral Multiplication and Contributes to Enhanced Replication Ability of Highly Pathogenic or L1 PRRSV

Viruses, 2022
Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) with enhanced replication capability emerged in China and has become dominant epidemic strain since 2006.
Junyao Xiong, Xingyang Cui, Kuan Zhao, Qian Wang, Xinyi Huang, Dongyan Li, Fang Yu, Yongbo Yang, Di Liu, Zhijun Tian, Xuehui Cai, Tongqing An   +11 more
doaj   +1 more source

PRRSV, the virus

Veterinary Research, 2000
Porcine reproductive and respiratory syndrome virus (PRRSV) is a positive-strand RNA virus that belongs to the Arteriviridae family. PRRSV grows in primary alveolar macrophages and in monkey kidney cell lines. The genomic RNA is approximately 15 kb.
openaire   +3 more sources

Identification of MYH9 Key Domain Involved in the Entry of PRRSV Into Permissive Cells

Frontiers in Microbiology, 2022
Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen that causes huge losses economically to the pig industry worldwide. Previous research suggested that receptor dependence is necessary for PRRSV infection. MYH9 and CD163
Liangliang Li, Weiyao Sun, Qifan Hu, Tongtong Wang, Guang Zhu, Qin Zhao, En-Min Zhou   +6 more
doaj   +1 more source

MYH9 Key Amino Acid Residues Identified by the Anti-Idiotypic Antibody to Porcine Reproductive and Respiratory Syndrome Virus Glycoprotein 5 Involve in the Virus Internalization by Porcine Alveolar Macrophages

Viruses, 2019
MYH9 has been identified as an indispensable cellular protein for porcine reproductive and respiratory syndrome virus (PRRSV) entry into permissive cells using the monoclonal anti-idiotypic antibody (Mab2-5G2) recognizing an antibody that specifically ...
Liangliang Li, Lu Zhang, Qifan Hu, Liang Zhao, Yuchen Nan, Gaopeng Hou, Yiyang Chen, Ximeng Han, Xiaolei Ren, Qin Zhao, Hu Tao, Zhenzhao Sun, Gaiping Zhang, Chunyan Wu, Jingfei Wang, En-Min Zhou   +15 more
doaj   +1 more source

The structural biology of PRRSV

Virus Research, 2010
Porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped, positive-sense single-stranded RNA virus belonging to the Arteriviridae family. Arteriviruses and coronaviruses are grouped together in the order Nidovirales, based on similarities in genome organization and expression strategy.
openaire   +2 more sources

PP2A Facilitates Porcine Reproductive and Respiratory Syndrome Virus Replication by Deactivating irf3 and Limiting Type I Interferon Production

Viruses, 2019
Protein phosphatase 2A (PP2A), a major serine/threonine phosphatase in mammalian cells, is known to regulate the kinase-driven intracellular signaling pathways.
Jiayu Xu, Lu Zhang, Yunfei Xu, He Zhang, Junxin Gao, Qian Wang, Zhijun Tian, Lv Xuan, Hongyan Chen, Yue Wang   +9 more
doaj   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Porcine reproductive and respiratory syndrome (PRRS) developments: An in-depth review of recent findings

Open Veterinary Journal
The porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) belonging to the Arteriviridae family is the cause of PRRS disease. After being discovered for the first time in the United States in 1987, this illness quickly expanded to Canada ...
Rimayanti Rimayanti, Aswin Rafif Khairullah, Tita Damayanti Lestari, Tatik Hernawati, Sri Mulyati, Suzanita Utama, Ratna Damayanti, Ikechukwu Benjamin Moses, Sheila Marty Yanestria, Muhammad Khaliim Jati Kusala, Ricadonna Raissa, Ima Fauziah, Syahputra Wibowo, Agung Prasetyo, Mo Awwanah, Kartika Afrida Fauzia   +15 more
doaj   +1 more source

MOLECULAR AND PATHOLOGICAL STUDIES OF POST-WEANING MULTI-SYSTEMIC WASTING SYNDROME AMONG PIGLETS IN KERALA, INDIA [PDF]

Exploratory Animal and Medical Research, 2019
Post weaning multi systemic wasting syndrome (PMWS) is an economically important porcine viral associated diseases caused by porcine circovirus 2(PCV2) in weaned piglets worldwide. Recently, the presence of PCV2 was reported in pig population of Kerala.
R. Sairam, B. Dhanush Krishna, K. Krithiga, I. S. Sajitha, P. M. Priya, Chintu Ravishankar, Mammen J. Abraham   +6 more
doaj  

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source