Results 41 to 50 of about 10,101 (182)

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

VIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song, Lulai Xu, Weilin Wu, Fei Xie, Yantong Pan, Tiantian Yang, Xiaoxia Xu, Yanyin Lin, Lihua Zhang, Jiahui Zhou, Junyou Zhou, Linping Li, Zhanhui Wang, Weijing Yi, Jing Wang   +14 more
wiley   +1 more source

Role of CD163 in PRRSV infection

Virology
Porcine reproductive and respiratory syndrome virus (PRRSV) is a highly infectious agent that poses a significant economic threat to the global swine industry. Efficient viral entry relies on interactions with cellular receptors, with CD163-a cysteine-rich scavenger receptor found on porcine alveolar macrophages (PAMs)-playing a critical role ...
Raymond R.R. Rowland, Alberto Brandariz-Nuñez   +1 more
openaire   +2 more sources

Immunity to PRRSV: Double-edged sword

Veterinary Microbiology, 1997
The immune system is a double-edged sword for porcine reproductive and respiratory syndrome virus (PRRSV) infection. On one edge PRRSV has a predilection for immune cells and the disease manifestations can be linked directly to changes in the immune system.
Molitor, T.W., Bautista, E.M., Choi, C.S.   +2 more
openaire   +2 more sources

The Performance of Seven Molecular Methods for the Detection of PRRSV [PDF]

Acta Veterinaria, 2020
Abstract Porcine Reproductive and Respiratory Syndrome is a viral disease of swine characterized by reproductive failure of breeding animals and respiratory disorders in all categories. The first PRRS case in Serbia was recorded in 2001 after illegal import of boar semen.
Milićević, Vesna, Kureljušić, Branislav, Veljović, Ljubiša, Valčić, Miroslav, Stević, Nataša, Savić, Božidar, Radojičić, Sonja   +6 more
openaire   +4 more sources

Identification of SNPs Associated With mRNA Expression Differences of the Complement Receptor Type 1‐Like Gene in Landrace Weaned Piglets

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
ABSTRACT Objective The aim of this study is to investigate the association between single nucleotide polymorphisms (SNPs) of porcine complement receptor 1‐like (CR1‐like) gene and its mRNA expression. Methods SNP identification, qRT‐PCR absolute quantification, linkage disequilibrium analysis and dual‐luciferase reporter assay were performed using 392 ...
Wei Yin, Jiachen Cheng, Qiongyu Li, Luyang Xu, Hongquan Li, Kuohai Fan, Zhenbiao Zhang, Na Sun, Panpan Sun, Huizhen Yang   +9 more
wiley   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4619-4639, July 2026.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

MiR-320 inhibits PRRSV replication by targeting PRRSV ORF6 and porcine CEBPB

Veterinary Research
AbstractPorcine reproductive and respiratory syndrome (PRRS), a highly contagious disease caused by Porcine reproductive and respiratory syndrome virus (PRRSV), results in huge economic losses to the world pig industry. MiRNAs have been reported to be involved in regulation of viral infection.
Xiaoxiao Gao, Xiangbin You, Guowei Wang, Mengtian Liu, Longlong Ye, Yufeng Meng, Gan Luo, Dequan Xu, Min Liu   +8 more
openaire   +3 more sources

Dijagnostika i karakteristike simultane PRRSV-1 I PRRSV-2 infekcije [PDF]

, 2023
Porcine reproductive and respiratory syndrome virus (PRRSV) was first discovered in Serbia in 2001. PRRSV belongs to the family Arteriviridae and is further classified into two genotypes, genotype PRRSV-1 and PRRSV-2. While PRRSV-1 mainly causes respiratory symptoms, PRRSV-2 leads to reproductive disorders.
Milićević, Vesna, Glišić, Dimitrije, Veljović, Ljubiša, Savić, Božidar, Kureljušić, Branislav   +4 more
openaire  

Discovery of Novel Viruses and Common Contaminants From Unmapped DNA and RNA in Pigs and Chickens Under Different Housing Conditions

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Unmapped sequencing reads in livestock often contain valuable information about pathogens but are typically discarded. We analyzed blood‐derived DNA and RNA from chickens and pigs kept under high‐ and low‐biosecurity conditions, focusing on unmapped reads.
Martijn F. L. Derks, Bert Dibbits, Richard P. M. A. Crooijmans, Kim Lensing   +3 more
wiley   +1 more source

Vectored vaccines to protect against PRRSV

Virus Research, 2010
PRRSV is the causative agent of the most important infectious disease affecting swine herds worldwide, producing great economic losses. Commercially available vaccines are only partially effective in protection against PRRSV. Moreover, modified live vaccines may allow virus shedding, and could revert generating virulent phenotypes.
Cruz, Jazmina L. G., Zuniga, Sonia, Becares, Martina, Sola, Isabel, Ceriani, Juan E., Juanola, Sandra, Plana, Juan, Enjuanes, Luis   +7 more
openaire   +5 more sources