Results 71 to 80 of about 10,101 (182)

Genetic Diversity, Recombination, and Pathogenicity of Porcine Epidemic Diarrhea Virus Strains Circulating in China During 2023–2024

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal piglets, posing a persistent threat to the global swine industry. Despite extensive vaccination, PEDV continues to circulate in China, underscoring the need for updated molecular epidemiological surveillance.
Yunlei Cao, Ahui Cui, Xin Chen, Yang Cheng, Rongfeng Tang, Hui Zeng, Yuchen Li, Qian Yang, Linzhu Ren   +8 more
wiley   +1 more source

Epidemiological surveillance and economic impact analysis of different porcine reproductive and respiratory syndrome virus infection statuses in 23 breeding pig farms in Hubei, China

Animal Diseases
Porcine reproductive and respiratory syndrome virus (PRRSV) has emerged as a significant threat to the pig farming industry worldwide, resulting in considerable economic losses. However, few reports detail its economic impact on the pig farming sector. A
Huifeng Zhao, Jingwei Zhou, Min Zhang, Xiutao Yang, Zhaofang Xi, Qingxia Gao, Rui Fang, Pengfei Zhao, Junlong Zhao   +8 more
doaj   +1 more source

Establishment of Systems to Enable Isolation of Porcine Monoclonal Antibodies Broadly Neutralizing the Porcine Reproductive and Respiratory Syndrome Virus

Frontiers in Immunology, 2019
The rapid evolution of porcine reproductive and respiratory syndrome viruses (PRRSV) poses a major challenge to effective disease control since available vaccines show variable efficacy against divergent strains.
David Goldeck, Dana M. Perry, Dana M. Perry, Jack W. P. Hayes, Jack W. P. Hayes, Luke P. M. Johnson, Luke P. M. Johnson, Jordan E. Young, Parimal Roychoudhury, Parimal Roychoudhury, Elle L. McLuskey, Elle L. McLuskey, Katy Moffat, Arjen Q. Bakker, Mark J. Kwakkenbos, Jean-Pierre Frossard, Raymond R. R. Rowland, Michael P. Murtaugh, Simon P. Graham, Simon P. Graham   +19 more
doaj   +1 more source

A centralised immunogen approach to develop a more broadly protective modified live porcine reproductive and respiratory syndrome virus 1 vaccine candidate

npj Vaccines
More efficacious vaccines are required to improve control of porcine reproductive and respiratory syndrome viruses (PRRSV). One strategy that has shown promise is the use of centralized antigens, generated from consensus sequence data. Here, we evaluated
Rory C. F. de Brito, Yashar Sadigh, Joseph Bowman, Stephanie Clive, Ben Jackson, Miriam Pedrera, Fraser Crofts, Matthieu Bernard, Fabian Z. X. Lean, Alejandro Núñez, Julian Seago, Jean-Pierre Frossard, Simon P. Graham   +12 more
doaj   +1 more source

Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression

Virulence
Porcine reproductive and respiratory syndrome virus (PRRSV) has a disastrous impact on the global swine industry. Even though PRRS commercial vaccines can provide homologous protection, broadly effective anti-PRRSV strategies are still in urgent need ...
Ming Qiu, Xinshuai Li, Shuai Li, Shubin Li, Ningjun Xie, Zhe Sun, Hong Lin, Jianzhong Zhu, Kegong Tian, Nanhua Chen   +9 more
doaj   +1 more source

A chimeric strain of porcine reproductive and respiratory syndrome virus 2 derived from HP-PRRSV and NADC30-like PRRSV confers cross-protection against both strains

Veterinary Research
Porcine reproductive and respiratory syndrome (PRRS) is one of the most significant swine viral infectious diseases worldwide. Vaccination is a key strategy for the control and prevention of PRRS.
Yang Li, Yumiao Wang, Xiuxiu Pei, Shao Chen, Yang Jing, Yongshuai Wu, Zhiqian Ma, Zhiwei Li, Zifang Zheng, Yingtong Feng, Lele Xu, Xiao Liu, Xuyang Guo, Haixue Zheng, Shuqi Xiao   +14 more
doaj   +1 more source

Etiological Detection, Isolation, and Pathogenicity of Porcine Reproductive and Respiratory Syndrome Virus in China

Veterinary Sciences
Due to its high genomic variability, the epidemiological landscape of porcine reproductive and respiratory syndrome virus (PRRSV) has become increasingly complex in recent years.
Yingbin Du, Jingyi Chen, Tianze Ren, Chunying Xie, Yiye Zhang, Liurong Fang, Yanrong Zhou   +6 more
doaj   +1 more source

Single-cell RNA sequencing analysis reveals a novel porcine alveolar macrophage subtype with high SLAMF7 expression promoting PRRSV infection

Virulence
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major and highly contagious swine pathogen that severely impacts the global pork industry.
Ankang Hu, Yao Guo, Yusi Zhou, Piao Chen, Yuhua Zhu, Tingjun Liu, Lianlian Wu, Dandan Qiao, Zhutao Huang, Yang Chen, Xufeng Han, Jing Liu, Quangang Chen   +12 more
doaj   +1 more source

Deciphering immune features and cellular heterogeneity in PRRSV infection via single-cell RNA sequencing

Journal of Virology
Porcine reproductive and respiratory syndrome virus (PRRSV), a major immunosuppressive pathogen, inflicts substantial economic losses on the global swine industry.
Jianda Li, Yue Liang, Yuyu Zhang, Yulin Xu, Fei Liu, Luogang Ding, Yu Wang, Zhihao Zhang, Zhi Chen, Wenbo Sun, Jiang Yu, Jiaqiang Wu   +11 more
doaj   +1 more source

Genetic variation and recombination analysis of the GP5 gene of the porcine reproductive and respiratory syndrome virus in Thailand

Frontiers in Veterinary Science
IntroductionPorcine reproductive and respiratory syndrome (PRRS) is a significant threat to the global swine industry, and its prevalence in Thailand spans over two decades.MethodsTo understand the genetic variation and recombination of the PRRS virus ...
Yajie Zheng, Gan Li, Kexin Liu, Qin Luo, Wenchao Sun, Mengmeng Zhao   +5 more
doaj   +1 more source