Results 11 to 20 of about 16,807 (206)

PRRSV Non-Structural Proteins Orchestrate Porcine E3 Ubiquitin Ligase RNF122 to Promote PRRSV Proliferation [PDF]

open access: yesViruses, 2022
Ubiquitination plays a major role in immune regulation after viral infection. An alternatively spliced porcine E3 ubiquitin ligase RNF122 promoted PRRSV infection and upregulated in PRRSV-infected PAM cells was identified.
Ruiqi Sun   +9 more
semanticscholar   +4 more sources

The jigsaw of PRRSV virulence.

open access: yesVeterinary Microbiology, 2021
Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of the, probably, most economically important disease for the pig industry worldwide. This disease, characterised by producing reproductive failure in sows and respiratory problems in growing pigs, appeared in the late 1980s in the United States and Canada.
I. Ruedas-Torres   +6 more
semanticscholar   +5 more sources

A Natural Recombinant NADC30-Like PRRSV Strain in China: Intersection of CH-1a, QYYZ, and JXA1 Lineages. [PDF]

open access: yesTransbound Emerg Dis
Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major threat to global swine production. In this study, a novel strain (PRRSV‐AH1) was isolated during a respiratory disease outbreak at a commercial swine operation in Anhui Province, China. Viral replication in MARC‐145 cells was confirmed by observing cytopathic effects (CPEs) and
Zhang H   +6 more
europepmc   +2 more sources

Progress in Structure and Function of GP5 Protein of Porcine Reproductive and Respiratory Syndrome Virus

open access: yesGuangdong nongye kexue, 2023
Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease caused by porcine reproductive and respiratory syndrome virus (PRRSV).
Pu KANG   +4 more
doaj   +1 more source

Refining PRRSV-2 genetic classification based on global ORF5 sequences and investigation of their geographic distributions and temporal changes

open access: yesMicrobiology spectrum, 2023
Porcine reproductive and respiratory syndrome virus (PRRSV) is an important swine pathogen affecting the global swine industry. The first open reading frame 5 (ORF5)-based genetic lineage classification system describing global PRRSV-2 genetic diversity ...
Wannarat Yim-im   +8 more
semanticscholar   +1 more source

Efficacy of a Commercial PRRSV Vaccine on NADC34-Like PRRSV Challenge

open access: yesTransboundary and Emerging Diseases, 2023
NADC34-like porcine reproductive and respiratory syndrome virus (PRRSV) has become endemic in some provinces of China and caused huge economic losses to local pig industry. The increased reports of NADC34-like PRRSV outbreaks in vaccinated pig herds suggest the limited protection of immunization with commercial vaccines.
Lili Yuan   +5 more
openaire   +2 more sources

Progress in PRRSV Infection and Adaptive Immune Response Mechanisms

open access: yesViruses, 2023
Since its discovery, Porcine reproductive and respiratory syndrome (PRRS) has had a huge impact on the farming industry. The virus that causes PRRS is Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), and because of its genetic diversity and ...
Huanchang Cai   +5 more
semanticscholar   +1 more source

In Vivo and In Vitro Characterization of the Recently Emergent PRRSV 1-4-4 L1C Variant (L1C.5) in Comparison with Other PRRSV-2 Lineage 1 Isolates

open access: yesViruses, 2023
The recently emerged PRRSV 1-4-4 L1C variant (L1C.5) was in vivo and in vitro characterized in this study in comparison with three other contemporary 1-4-4 isolates (L1C.1, L1A, and L1H) and one 1-7-4 L1A isolate.
Gaurav Rawal   +14 more
semanticscholar   +1 more source

Lactate-lactylation-HSPA6 axis promotes PRRSV replication by impairing IFN-β production

open access: yesJournal of Virology, 2023
Lactate, traditionally considered a metabolic by-product, has recently been identified as a substrate for the induction of lactylation, a newly identified epigenetic modification that plays an important role in the regulation of host gene expression. Our
Yu Pang   +4 more
semanticscholar   +1 more source

Genetic Variability and Recombination of the NSP2 Gene of PRRSV-2 Strains in China from 1996 to 2021

open access: yesVeterinary Sciences, 2023
Simple Summary Genetic variability and recombination of the NSP2 gene are of great significance in gaining an in-depth understanding of the prevalence of PRRSV in China over the past 25 years.
Hang Zhang   +7 more
semanticscholar   +1 more source

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