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Evaluation of PRRSV vaccine efficacy following infection with PRRSV 1-7-4
Our objective was to evaluate whether porcine reproductive and respiratory syndrome virus (PRRSV) vaccination improved mortality and morbidity following experimental infection with a PRRSV restriction fragment length polymorphism 1-7-4. Results indicated that mortality and morbidity were significantly lower for vaccinated pigs as compared to ...
Erin Little +7 more
openaire +1 more source
Novel Lentivirus-Based Method for Rapid Selection of Inhibitory Nanobody against PRRSV
The emergence and re-emergence of porcine reproductive and respiratory syndrome virus (PRRSV) has resulted in huge economic losses for the swine industry. Current vaccines are of limited efficacy against endemic circulating PRRSV variants. New strategies
Ze-Hui Liu +4 more
doaj +1 more source
Chunyan Shao,1– 5,* Ziwei Yu,1– 5,* Tongwang Luo,1– 5,* Bin Zhou,1– 5 Quanjiang Song,1– 5 Zhuoyue Li,1– 5 Xiaoqiang Yu,1– 5 Sheng Jiang,1– 5 Yingshan Zhou,1– 5 Wanyu Dong,1– 5 Xingdong Zhou,1– 5 Xiaodu Wang,1– 5 Houhui Song1– 5 1Key ...
Shao C +12 more
doaj
Molecular Characterization of the Nsp2 and ORF5s of PRRSV Strains in Sichuan China during 2012–2020
Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen that poses a serious threat to the global pig industry. Sichuan Province is one of the largest pig breeding provinces in China.
Jun Zhao +9 more
doaj +1 more source
Bacillus subtilis sups. chungkookjang produces a higher molecular mass poly-γ-glutamic acid (γ-PGA). Recently, previous studies have demonstrated immune stimulation and an antitumor effect of the high molecular mass γ-PGA using various mouse models ...
Seo Byoung-Joo +8 more
doaj +1 more source
The papain-like cysteine protease 2 (PLP2) within the N-terminus of the porcine reproductive and respiratory syndrome virus (PRRSV) nsp2 replicase protein specifies a deubiquitinating enzyme (DUB), but its biochemical properties and the role in infection
Shaochuan Zhou +10 more
doaj +1 more source
Porcine reproductive and respiratory syndrome (PRRS) is an infectious viral disease that causes great harm to the pig industry. PRRS virus (PRRSV), the causative agent of PRRS, is characterized by severe reproductive failure and respiratory confusion ...
Pengfei Zhao +4 more
doaj +1 more source
The Innate Immune DNA Sensing cGAS-STING Signaling Pathway Mediates Anti-PRRSV Function
Porcine reproductive and respiratory syndrome virus (PRRSV) modulates host innate immunity which plays a key role against PRRSV infection. As a RNA virus, PRRSV is mainly sensed by innate immune RNA receptors, whereas the role of innate immune DNA ...
Yulin Xu +12 more
doaj +1 more source
Restriction fragment length polymorphism (RFLP) of open reading frames 6 and 7 was applied to comparative genetic analysis of live attenuated vaccine strains (Amervac-PRRS/A3, Porcilis PRRS, Ingelvac PRRS) of porcine reproductive and respiratory syndrome
E. Kosinova, I. Psikal
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Antibody-dependent enhancement (ADE) is an event in preexisting sub-, or non-neutralizing antibodies increasing the viral replication in its target cells.
Liujun Zhang +8 more
doaj +1 more source

