Reservoir of Bacterial Exotoxin Genes in the Environment
International Journal of Microbiology, 2010 Many bacteria produce secreted virulence factors called exotoxins. Exotoxins are often encoded by mobile genetic elements, including bacteriophage (phage). Phage can transfer genetic information to the bacteria they infect.
Veronica Casas +4 more
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PLoS ONE, 2010 BackgroundWe have previously explored a therapeutic strategy for specifically targeting the profibrotic activity of IL-13 during experimental pulmonary fibrosis using a fusion protein comprised of human IL-13 and a mutated form of Pseudomonas aeruginosa ...
Rogério S Rosada +8 more
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Chimeric carrier proteins for targeted delivery of tumor antigens to professional antigen presenting cells [PDF]
, 2007 Tumor-specific T lymphocytes can be regarded as a highly effective mechanism for tumor rejection. A substantial number of T-cell defined tumor antigens including mutated oncoproteins and differentiation antigens have been identified.
Kursar, Mischo +4 more
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Cooperative research and development opportunities with the National Cancer Institute [PDF]
The Office of Technology Development (OTD) of the National Cancer Institute (NCI) is responsible for negotiating Cooperative Research and Development Agreements (CRADAs), whereby the knowledge resulting from NCI investigators' government-sponsored ...
Sybert, Kathleen
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Effect of a nematicidal Bacillus thuringiensis strain on free- living nematodes : 3. Characterization of the intoxication process [PDF]
, 1996 La toxicité de #Bacillus thuringiensis$ est fonction de la température. L'incubation de #Caenorhabditis elegans$ avec des souches de #B. thuringiensis$ à 16, 20 et 25°C montre que la toxicité décroît en même temps que la température.
Arnaut, G. +5 more
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Pseudomonas Exotoxin A Based Toxins Targeting Epidermal Growth Factor Receptor for the Treatment of Prostate Cancer. [PDF]
Toxins (Basel), 2020 Fischer A +4 more
europepmc +1 more source
Pseudomonas aeruginosa exotoxin A and keratitis in mice.
Investigative ophthalmology & visual science, 2002 To determine the importance of Pseudomonas aeruginosa exotoxin A (ETA) as a virulence factor in corneal disease.Isogenic mutants deficient in ETA were constructed in P. aeruginosa strains PAO1 and ATCC 19660 by allelic exchange and then evaluated for virulence in a mouse model of bacterial keratitis.
Christopher M, Pillar, Jeffery A, Hobden
openaire +1 more source
Development of novel cytotoxin therapy that targets tumor-associated surface molecules of biliary tract carcinoma [PDF]
, 2011 課題番号 ...
SHODA JUNICHI, 正田 純一
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Different Approaches For Protein Engineering In Industrial Biotechnology [PDF]
, 2011 Protein engineering is the novel field which has wide applications from pharmaceutics, industry, commercial, laundry and research. It may apply rational design or non rational design or both.
Israr Khan, Muhammad Waheed Akhtar
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Inhibition of Pseudomonas-Aeruginosa Exoenzyme Expression by Subinhibitory Antibiotic Concentrations [PDF]
, 1989 Grimwood, K, To, M, Rabin, HR, Woods, DE
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