Pseudomonas exotoxin a - Open Access .click

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Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS.

PLoS ONE, 2012
Homologs of the transcriptional regulator PtxS are omnipresent in Pseudomonas, whereas PtxR homologues are exclusively found in human pathogenic Pseudomonas species.
Abdelali Daddaoua +5 more
doaj +1 more source

Molecular Detection of tox A Gene in Multidrug Resistance Pseudomonas aeruginosa Isolated from Burn Infections

Medical Journal of Babylon
Background: Exotoxin A (ExoA) is the most widespread and toxic virulence agent among pathogenic Pseudomonas aeruginosa species that acquire adenosine diphosphate-ribosyltransferase activity belonging to the class of exotoxins secreted by pathogenic ...
Zahraa Hamza Merza, Rabab Omran
doaj +1 more source

Reduced cytotoxicity by mutation of lysine 590 of Pseudomonas exotoxin can be restored in an optimized, lysine-free immunotoxin. [PDF]

Immunother Adv, 2022
Ammon A +7 more
europepmc +1 more source

Isolation Virulence genes ETA, OPrL, gyrB in Pseudomonas aeruginosa clinical samples from hospitals in Kerman by Multiplex-PCR [PDF]

, 2016
زمینه و هدف: سودوموناس آئروژینوزا یک پاتوژن فرصت طلب و عامل عفونت های بیمارستانی و مرگ و میر به خصوص در بیماران با ضعف سیستم ایمنی می باشد و مقاومت ذاتی به مواد ضد میکروبی منجر به مشکلاتی در درمان عفونت های آن می شود.
Amini, K., Kamali, A.
core +1 more source

Reservoir of Bacterial Exotoxin Genes in the Environment

International Journal of Microbiology, 2010
Many bacteria produce secreted virulence factors called exotoxins. Exotoxins are often encoded by mobile genetic elements, including bacteriophage (phage). Phage can transfer genetic information to the bacteria they infect.
Veronica Casas +4 more
doaj +1 more source

Pseudomonas Exotoxin A Based Toxins Targeting Epidermal Growth Factor Receptor for the Treatment of Prostate Cancer. [PDF]