Virology, 2019 Molecular adjuvants are vaccine delivery vehicle to increase specific antigens effectiveness. Herein, we concentrated on IgG Fc, an effective molecular adjuvant, to develop novel pseudorabies virus (PRV) subunit vaccines. Two major protective antigen genes of PRV were constructed and linked into the mouse IgG Fc fragment.
Jianglong, Li +6 more
openaire +2 more sources
The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes [PDF]
, 2019 Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs.
Bertzbach, Luca D. +7 more
core +2 more sources
Lyophilisation of influenza, rabies and Marburg lentiviral pseudotype viruses for the development and distribution of a neutralisation-assay based diagnostic kit [PDF]
, 2014 Pseudotype viruses (PVs) are chimeric, replication-deficient virions that mimic wild-type virus entry mechanisms and can be safely employed in neutralisation assays, bypassing the need for high biosafety requirements and performing comparably to ...
Assar +44 more
core +3 more sources
VaccinesInfection of pigs with the pseudorabies virus (PRV) causes significant economic losses in the pig industry. Immunization with live vaccines is a crucial aspect in the prevention of pseudorabies in swine.
Yan Liu +10 more
doaj +1 more source
Aptamer-Based QCM-Sensor for Rapid Detection of PRRS Virus
Proceedings, 2018 Porcine reproductive and respiratory syndrome (PRRS) is caused by an RNA virus and has substantial economic impact on swine industry. Screening pigs for infection is the best way to prevent spreading the disease. For that purpose, we developed biosensors
Chakpetch Kuitio +2 more
doaj +1 more source
Characterization of the Dynamic Transcriptome of a Herpesvirus with Long-read Single Molecule Real-Time Sequencing [PDF]
, 2017 Herpesvirus gene expression is co-ordinately regulated and sequentially ordered during productive infection. The viral genes can be classified into three distinct kinetic groups: immediate-early, early, and late classes.
Balázs, Zsolt +5 more
core +1 more source
Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP [PDF]
, 2008 Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Bienkowska-Szewczyk, Krystyna +19 more
core
Experimental Dual Infection of Specific Pathogen‐Free Pigs with Porcine Reproductive and Respiratory Syndrome Virus and Pseudorabies Virus [PDF]
, 2003 Isao Shibata +3 more
openalex +1 more source
Cathelicidin CATH-B1 Inhibits Pseudorabies Virus Infection via Direct Interaction and TLR4/JNK/IRF3-Mediated Interferon Activation [PDF]
, 2023 Chao Ye +8 more
openalex +1 more source
Veterinary SciencesDiseases associated with porcine circovirus type 2 (PCV2) and pseudorabies virus (PRV) significantly affect the economy of pig farms, particularly when combined infections lead to bacterial co-infections.
Fulai Yu +5 more
doaj +1 more source