Results 1 to 10 of about 8,174 (164)

The Deletion of US3 Gene of Pseudorabies Virus (PRV) ΔgE/TK Strain Induces Increased Immunogenicity in Mice [PDF]

Vaccines, 2022
Re-emerging pseudorabies (PR) caused by pseudorabies virus (PRV) variant has been prevailing among immunized herds in China since 2011, indicating that commercially available PR vaccine strains couldn’t provide complete protection against novel, epidemic
Meng-Meng Deng, Ya-Wei Sun, Chen-Meng Ding, Xi-Ya Xu, Zi-Yi Guo, Zi-Wei Han, Chen-Zhe Lv, Jiang-Kun Qi, Yong-Tao Li, Xia Yang, Lin-Yang Yu, Lu Chen   +11 more
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Antiviral activity of nitazoxanide against pseudorabies virus infection in vitro [PDF]

Frontiers in Veterinary Science
Pseudorabies (PR), an infectious disease caused by pseudorabies virus (PRV), has been responsible for substantial economic losses within the global swine industry.
Lei Tan, Pei Zhu, Zhaori Getu, Xi Yang, Shiling Zheng, Yuqing Duan, Jinping Wang, Yi Zhou, Yuyang Hu, Yijing Wang, Yuying Yang, Mengting Zuo, Jun Yao   +12 more
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Pseudorabies virus DNA polymerase processivity factor pUL42 inhibits type I IFN production by negatively regulating cGAS-STING signaling pathway [PDF]

Journal of Virology
Pseudorabies (PR), caused by the PR virus (PRV), is an acute infectious disease in livestock and various wild animals. PRV has developed several immune evasion mechanisms to antagonize the host’s antiviral immune response.
Guangqiang Ye, Jiaxiu Gao, Haoxuan Cao, Xiaohong Liu, Hongyang Liu, Shanghui Wang, Yunfei Liu, Longfei Han, Qiongqiong Zhou, Yandong Tang, Jin Tian, Liping Huang, Li Huang, Zhaoxia Zhang, Changjiang Weng   +14 more
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The Epidemiology and Variation in Pseudorabies Virus: A Continuing Challenge to Pigs and Humans

Viruses, 2022
Pseudorabies virus (PRV) can infect most mammals and is well known for causing substantial economic losses in the pig industry. In addition to pigs, PRV infection usually leads to severe itching, central nervous system dysfunction, and 100% mortality in ...
Qingyun Liu, Yan Kuang, Yafei Li, Huihui Guo, Chuyue Zhou, Shibang Guo, Chen Tan, Bin Wu, Huanchun Chen, Xiangru Wang   +9 more
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Construction and Immunogenicity of a Recombinant Pseudorabies Virus Variant With TK/gI/gE/11k/28k Deletion

Frontiers in Veterinary Science, 2022
In China, the re-emerging pseudorabies virus (PRV) variant has caused large-scale outbreaks of pseudorabies in swine herds with classical PRV vaccine immunization since late 2011.
Shijun Yan, Baicheng Huang, Xiaofei Bai, Ying Zhou, Linghua Guo, Tongyan Wang, Yihong Shan, Yuzhou Wang, Feifei Tan, Kegong Tian   +9 more
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Progress of Research into Novel Drugs and Potential Drug Targets against Porcine Pseudorabies Virus

Viruses, 2022
Pseudorabies virus (PRV) is the causative agent of pseudorabies (PR), infecting most mammals and some birds. It has been prevalent around the world and caused huge economic losses to the swine industry since its discovery.
Mo Zhou, Muhammad Abid, Shinuo Cao, Shanyuan Zhu   +3 more
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Recombinant Pseudorabies Virus Usage in Vaccine Development against Swine Infectious Disease

Viruses, 2023
Pseudorabies virus (PRV) is the pathogen of pseudorabies (PR), which belongs to the alpha herpesvirus subfamily with a double stranded DNA genome encoding approximately 70 proteins.
Mo Zhou, Muhammad Abid, Shinuo Cao, Shanyuan Zhu   +3 more
doaj   +1 more source

Genome editing of pseudorabies virus in the CRISPR/Cas9 era: a mini-review

Frontiers in Veterinary Science, 2023
Pseudorabies virus (PRV) is an important swine virus that has a significant impact on the global swine industry. PRV is a member of the herpesvirus family, specifically the alphaherpesvirus subfamily, and has been extensively utilized as a prototype ...
Hai-Ming Wang, Yang-Yang Qiao, Bing-Yan Cai, Ju Tan, Lei Na, Lei Na, Yu Wang, Hui Lu, Yan-Dong Tang, Yan-Dong Tang   +9 more
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Cross species transmission of pseudorabies virus leads to human encephalitis and visual impairment: A case report

Frontiers in Neurology, 2022
Pseudorabies virus (PRV) is a common pig infectious disease. There have been few reports of PRV infection in humans. The patient in this article had acute onset, which was manifested by fever, epilepsy, disturbance of consciousness, and other symptoms ...
Hui Huang, Na Wang, Zhi-Bing Ai, Jun Chen, Wei Huang, Yi Bao   +5 more
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A case report of long-delayed diagnosis of pseudorabies virus encephalitis with endophthalmitis: lessons from metagenomic next generation sequencing

BMC Neurology, 2023
Background Pseudorabies virus (PRV) was thought to only infect animals. Recent studies have shown that it can also infect human. Case presentation We report a case of pseudorabies virus encephalitis and endophthalmitis, diagnosed 89 days after onset ...
Yi Zhang, Lei Fang, Yi Zhou, Yongqing Zhang, Bing Liang, Chuanzhu Yan, Ling Li   +6 more
doaj   +1 more source