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The Deletion of US3 Gene of Pseudorabies Virus (PRV) ΔgE/TK Strain Induces Increased Immunogenicity in Mice [PDF]

Vaccines, 2022
Re-emerging pseudorabies (PR) caused by pseudorabies virus (PRV) variant has been prevailing among immunized herds in China since 2011, indicating that commercially available PR vaccine strains couldn’t provide complete protection against novel, epidemic
Meng-Meng Deng, Ya-Wei Sun, Chen-Meng Ding, Xi-Ya Xu, Zi-Yi Guo, Zi-Wei Han, Chen-Zhe Lv, Jiang-Kun Qi, Yong-Tao Li, Xia Yang, Lin-Yang Yu, Lu Chen   +11 more
doaj   +4 more sources

Comparative Transcriptomic Analysis Reveals Divergent Host Cell Responses to Classical and Variant Pseudorabies Virus Strains [PDF]

Veterinary Sciences
Pseudorabies virus (PRV), also called suid alphaherpesvirus 1, is a double-stranded linear DNA virus belonging to the subfamily Alphaherpsvirinae of the family Herpesviridae [...]
Zihan Yang, Xi Yang, Yuqing Duan, Pei Zhu, Jinping Wang, Mengting Zuo, Yun Zhou, Kewei Fan, Lei Tan, Jun Yao   +9 more
doaj   +2 more sources

Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus [PDF]

BMC Microbiology, 2009
Background Pseudorabies virus (PRV) is an alphaherpesviruses whose native host is pig. PRV infection mainly causes signs of central nervous system disorder in young pigs, and respiratory system diseases in the adult.
Furlong RA, Jafer O, Zhang SJ, Yuan JF, Chausiaux OE, Sargent CA, Zhang GH, Affara NA   +7 more
doaj   +3 more sources

Pseudorabies virus (PRV) strain with defects in gE, gC, and TK genes protects piglets against an emerging PRV variant [PDF]

Journal of Veterinary Medical Science, 2020
Lin J, Li Z, Feng Z, Fang Z, Chen J, Chen W, Liang W, Chen Q.   +7 more
exaly   +2 more sources

Generation of Premature Termination Codon (PTC)-Harboring Pseudorabies Virus (PRV) via Genetic Code Expansion Technology [PDF]

Viruses, 2022
Zhi-Jun Tian, Shu-Jie Wang, Hao Zheng
exaly   +2 more sources

Implication of the Identification of an Earlier Pseudorabies Virus (PRV) Strain HLJ-2013 to the Evolution of Chinese PRVs [PDF]

Frontiers in Microbiology, 2020
Huimin Liu, Chunguo Liu, Zhenzhao Sun
exaly   +2 more sources

The Epidemiology and Variation in Pseudorabies Virus: A Continuing Challenge to Pigs and Humans

Viruses, 2022
Pseudorabies virus (PRV) can infect most mammals and is well known for causing substantial economic losses in the pig industry. In addition to pigs, PRV infection usually leads to severe itching, central nervous system dysfunction, and 100% mortality in ...
Qingyun Liu, Yan Kuang, Yafei Li, Huihui Guo, Chuyue Zhou, Shibang Guo, Chen Tan, Bin Wu, Huanchun Chen, Xiangru Wang   +9 more
doaj   +1 more source

Construction and Immunogenicity of a Recombinant Pseudorabies Virus Variant With TK/gI/gE/11k/28k Deletion

Frontiers in Veterinary Science, 2022
In China, the re-emerging pseudorabies virus (PRV) variant has caused large-scale outbreaks of pseudorabies in swine herds with classical PRV vaccine immunization since late 2011.
Shijun Yan, Baicheng Huang, Xiaofei Bai, Ying Zhou, Linghua Guo, Tongyan Wang, Yihong Shan, Yuzhou Wang, Feifei Tan, Kegong Tian   +9 more
doaj   +1 more source

Progress of Research into Novel Drugs and Potential Drug Targets against Porcine Pseudorabies Virus

Viruses, 2022
Pseudorabies virus (PRV) is the causative agent of pseudorabies (PR), infecting most mammals and some birds. It has been prevalent around the world and caused huge economic losses to the swine industry since its discovery.
Mo Zhou, Muhammad Abid, Shinuo Cao, Shanyuan Zhu   +3 more
doaj   +1 more source

Recombinant Pseudorabies Virus Usage in Vaccine Development against Swine Infectious Disease

Viruses, 2023
Pseudorabies virus (PRV) is the pathogen of pseudorabies (PR), which belongs to the alpha herpesvirus subfamily with a double stranded DNA genome encoding approximately 70 proteins.
Mo Zhou, Muhammad Abid, Shinuo Cao, Shanyuan Zhu   +3 more
doaj   +1 more source