Results 31 to 40 of about 8,243 (225)

Long-term Cre-mediated retrograde tagging of neurons using a novel recombinant pseudorabies virus [PDF]

, 2014
Brain regions contain diverse populations of neurons that project to different long-range targets. The study of these subpopulations in circuit function and behavior requires a toolkit to characterize and manipulate their activity in vivo.
Anthony M. Zador, Hassana K. Oyibo, Hysell V. Oviedo, Lynn W. Enquist, Petr Znamenskiy   +4 more
core   +2 more sources

A gD&gC-substituted pseudorabies virus vaccine strain provides complete clinical protection and is helpful to prevent virus shedding against challenge by a Chinese pseudorabies variant

BMC Veterinary Research, 2019
Background Since 2011, pseudorabies caused by a variant PRV has re-emerged in many Chinese Bartha-K61-vaccinated pig farms. An efficacious vaccine is necessary to control this disease.
Chuanjian Zhang, Yamei Liu, Saisai Chen, Yongfeng Qiao, Mingpeng Guo, Yating Zheng, Mengwei Xu, Zhisheng Wang, Jibo Hou, Jichun Wang   +9 more
doaj   +1 more source

Design of live-attenuated animal vaccines based on pseudorabies virus platform

Animal Diseases, 2022
Pseudorabies virus (PRV) is a double-stranded DNA virus with a genome approximating 150 kb in size. PRV contains many non-essential genes that can be replaced with genes encoding heterogenous antigens without affecting viral propagation. With the ability
Zhen Liu, Zhengjie Kong, Meng Chen, Yingli Shang   +3 more
doaj   +1 more source

Characterisation of pseudorabies virus in domestic pigs and wild boars in Croatia [PDF]

, 2014
Serological data imply that pseudorabies (Aujeszky’s disease) is present in domestic pigs and wild boars in Croatia. Therefore, this study included testing of brain tissue samples collected from 200 domestic pigs and 105 wild boars originating from ...
Bedeković, Tomislav, Brnić, Dragan, Dežđek, Danko, Jemeršić, Lorena, Keros, Tomislav, Prpić, Jelena, Roić, Besi   +6 more
core   +1 more source

Pseudorabies virus (PRV) injection into inguinal white adipose tissue v1 [PDF]

, 2019
We utilize pesudorabies virus (PRV) retrograde tracing in combination with reporter mice, iDISCO, and confocal/light sheet microscopy to identify the location of pre- and post-ganglionic neurons as well as nerves that selectively innervate the iWAT in the mouse.
Clara Huesing, Heike Muenzberg, Rui Zhang, Nathan Lee, Emily Qualls-Creekmore, Marie Francois   +5 more
openaire   +1 more source

A novel recombinant pseudorabies virus expressing parvovirus VP2 gene: Immunogenicity and protective efficacy in swine

Virology Journal, 2011
Background Porcine parvovirus (PPV) VP2 gene has been successfully expressed in many expression systems resulting in self-assembly of virus-like particles (VLPs) with similar morphology to the native capsid.
Chen Dishi, Shi Qian, Luo Yan, Yan Qigui, Xu Zhiwen, Guo Wanzhu, Chen Yang, Zhu Ling, Wang Xiaoyu   +8 more
doaj   +1 more source

Host-virus interactions in PK-15 cells infected with Pseudorabies virus Becker strain based on RNA-seq

Virus Research, 2022
Pseudorabies is a highly contagious viral disease caused by the pseudorabies virus (PRV), and it is one of the most devastating diseases for the swine industry worldwide.
Aishao Shangguan, Jingjin Li, Yumei Sun, Zhongzhu Liu, Shujun Zhang   +4 more
doaj   +1 more source

DDX56 inhibits PRV replication through regulation of IFN-β signaling pathway by targeting cGAS

Frontiers in Microbiology, 2022
Pseudorabies virus (PRV) is an agent of Aujeszky's disease, and causes great economic losses to pig farming. Re-outburst of pseudorabies implies that new control measures are urgently needed.
Jingying Xie, Jingying Xie, Xiangrong Li, Shunyu Yang, Zhenfang Yan, Lei Chen, Yanmei Yang, Dianyu Li, Xiangbo Zhang, Ruofei Feng, Ruofei Feng   +10 more
doaj   +1 more source

Comprehensive evaluation of the safety and immunogenicity of a gene-deleted variant pseudorabies virus attenuated vaccine

Veterinary Research, 2022
Pseudorabies virus (PRV) variant infections have caused a substantial economic impact on swine production in the absence of new powerful candidate vaccines.
Ling Li, Yongfeng Du, Yanbin Zhang, Pengyu Li, Xinyue Liu, Xin Zhang, Jing Li, Tong Zhang, Xin Li, Dong Xiao, Peng Liu, Peng Qi, Jin Xiao   +12 more
doaj   +1 more source

Huaier Polysaccharide Interrupts PRV Infection via Reducing Virus Adsorption and Entry

Viruses, 2022
A pseudorabies virus (PRV) novel virulent variant outbreak occurred in China in 2011. However, little is known about PRV prevention and treatment. Huaier polysaccharide has been used to treat some solid cancers, although its antiviral activity has not ...
Changchao Huan, Jingting Yao, Weiyin Xu, Wei Zhang, Ziyan Zhou, Haochun Pan, Song Gao   +6 more
doaj   +1 more source