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Pseudorabies Virus: From Pathogenesis to Prevention Strategies
Viruses, 2022 Pseudorabies (PR), also called Aujeszky’s disease (AD), is a highly infectious viral disease which is caused by pseudorabies virus (PRV). It has been nearly 200 years since the first PR case occurred.
Hui-Hua Zheng +3 more
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Progressive postnatal assembly of limbic-autonomic circuits revealed by central transneuronal transport of pseudorabies virus [PDF]
, 2000 The development of neuronal projections to a target and the establishment of synaptic connections with that target can be temporally distinct events, which typically are distinguished by functional assessments.
Card, JP, Levitt, P, Rinaman, L
core +1 more source
Structures of pseudorabies virus capsids
Nature Communications, 2022 Pseudorabies virus (PRV) is a major etiological agent of swine infectious diseases responsible for significant economic losses in the swine industry. The authors report the structures of the PRV A-capsid and C-capsid, shedding light on PRV’s assembly ...
Guosong Wang +18 more
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Pathogens, 2021 Suid alphaherpesvirus 1 (SuHV-1), better known as Pseudorabies virus (PrV), an alphaherpesvirus of swine, is the causative agent of Aujeszky’s Disease [...]
Barbara G. Klupp
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Interferon alpha suppresses alphaherpesvirus immediate early protein levels in sensory neurons, leading to the establishment of a latent infection [PDF]
, 2010 Alphaherpesviruses are a subfamily of the herpesviruses containing closely related human and animal pathogens, including human herpes simplex virus (HSV-1) and porcine pseudorabies virus (PRV)
De Regge, Nick +4 more
core
Advanced Science, Volume 13, Issue 24, 27 April 2026.In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
The Role of Latency-Associated Transcripts in the Latent Infection of Pseudorabies Virus
Viruses, 2022 Pseudorabies virus (PRV) can cause neurological, respiratory, and reproductive diseases in pigs and establish lifelong latent infection in the peripheral nervous system (PNS).
Jiahuan Deng +4 more
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Genome sequences of two pseudorabies virus strains isolated in Greece [PDF]
, 2016 Pseudorabies virus (species Suid herpesvirus 1) belongs to the genus Varicellovirus, subfamily Alphaherpesvirinae, family Herpesviridae, and is the causative agent of an acute and frequently fatal disease that affects mainly pigs.
Davison, Andrew J +7 more
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CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.This study establishes a whole‐brain monosynaptic input map to cholinergic neurons in the lower thoracic intermediolateral column (IML) using a cell‐type‐specific retrograde rabies tracing system in ChAT‐Cre mice. Our results reveal a widespread supraspinal network originating from five major brain divisions, including the telencephalon, diencephalon ...
Yuan‐jun Yang +9 more
wiley +1 more source
Interferon-gamma response of PBMC indicates productive pseudorabies virus (PRV) infection in swine
Veterinary Immunology and Immunopathology, 2004 In Chinese Meishan/German Landrace cross-bred swine F2 generation interferon gamma (IFN-gamma) production by peripheral blood mononuclear cells (PBMC) was determined directly ex vivo at different time points after survival of a virulent pseudorabies virus (PRV) infection. This reactivity was compared with the reactivity of naïve PBMC.
Hoegen, Bärbel +7 more
openaire +2 more sources