Results 61 to 70 of about 8,213 (212)

The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents

The Journal of Physiology, Volume 604, Issue 7, Page 2939-2957, 1 April 2026.
Abstract figure legend Our study demonstrates that both GABA and glycine mediate inhibitory postsynaptic currents in the ventrolateral/ventromedial medulla (VLM/VMM) and increasing the activity of inhibitory synapses facilitates glycine release. We found that presympathetic VLM/VMM neurons receive glycinergic inputs, which release both glycine and GABA,
Hong Gao, Lucie D. Desmoulins, Adrien J. R. Molinas, Courtney M. Dugas, Andrea Zsombok, Andrei V. Derbenev   +5 more
wiley   +1 more source

Isolation and Characterization of Two Pseudorabies Virus and Evaluation of Their Effects on Host Natural Immune Responses and Pathogenicity

Viruses, 2022
Pseudorabies, caused by the pseudorabies virus (PRV), is an acute fatal disease, which can infect rodents, mammals, and other livestock and wild animals across species.
Qiongqiong Zhou, Longfeng Zhang, Hongyang Liu, Guangqiang Ye, Li Huang, Changjiang Weng   +5 more
doaj   +1 more source

A novel non-mineral oil-based adjuvant. II. Efficacy of a synthetic sulfolipopolysaccharide in a squalane-in-water emulsion in pigs [PDF]

, 1994
The adjuvanticity of a sulfolipopolysaccharide (SLP) incorporated into a squalane-in-water emulsion (SLP/S/W) was compared with that of a mineral oil-in-water (O/W) adjuvant currently used in commercial porcine vaccines.
Dazelle, T. (T.), Groenveld, B. (B.), Hilgers, L.A.Th. (L. A Th), Luitjens, A. (A.), Platenburg, P.L.I. (P. L I), Weststrate, J.T.M.   +5 more
core   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

The immunity protection of intestine induced by pseudorabies virus del gI/gE/TK in piglets

Frontiers in Microbiology
Compared to the classical strain of Pseudorabies virus (PRV), the PRV variant exhibits stronger transmissibility and pathogenicity, causing immense disasters for the global pig industry. Based on this variant, our laboratory has preliminarily constructed
Yang Zhang, Lei Xu, Qian Tao, Zheyan Liu, Jianhua Wen, Tong Xu, Siyuan Lai, Yanru Ai, Zhiwen Xu, Zhiwen Xu, Ling Zhu, Ling Zhu   +11 more
doaj   +1 more source

The Valproic Acid Derivative Valpromide Inhibits Pseudorabies Virus Infection in Swine Epithelial and Mouse Neuroblastoma Cell Lines

Viruses, 2021
Pseudorabies virus (PRV) infection of swine can produce Aujeszky’s disease, which causes neurological, respiratory, and reproductive symptoms, leading to significant economic losses in the swine industry. Although humans are not the natural hosts of PRV,
Sabina Andreu, Inés Ripa, Beatriz Praena, José Antonio López-Guerrero, Raquel Bello-Morales   +4 more
doaj   +1 more source

The caudal pedunculopontine tegmental nucleus may be involved in the regulation of skeletal muscle activity by melanocortin-sympathetic pathway: a virally mediated trans-synaptic tracing study in spinally transected transgenic mice [PDF]

, 2017
Understanding neuroanatomical sympathetic circuitry and neuronal connections from the caudal pedunculopontine tegmental nucleus to skeletal muscle is important to the study of possible mechanisms of pedunculopontine tegmental nucleus (PPTg) and cuneiform
He, Zhi-Gang, Li, Zhi-Xiao, Liu, Bao-Wen, Liu, San-Guang, Manyande, Anne, Tian, Xuebi, Xiang, Hong-Bing, Zhang, Ding-Yu   +7 more
core   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

The Pseudorabies Virus DNA Polymerase Accessory Subunit UL42 Directs Nuclear Transport of the Holoenzyme [PDF]

, 2016
Pseudorabies virus (PRV) DNA replication occurs in the nuclei of infected cells and requires the viral DNA polymerase. The PRV DNA polymerase comprises a catalytic subunit, UL30, and an accessory subunit, UL42, that confers processivity to the enzyme ...
Chang-Ming Liu, Hong-Li Wu, Li Feng, Li-Ping Huang, Wen-Juan Du, Yan-Wu Wei, Yi-Ping Wang   +6 more
core   +6 more sources

The Construction and Immunogenicity Analyses of Recombinant Pseudorabies Virus With NADC30-Like Porcine Reproductive and Respiratory Syndrome Virus-Like Particles Co-expression

Frontiers in Microbiology, 2022
Porcine reproductive and respiratory syndrome (PRRS) and pseudorabies (PR) are highly infectious swine diseases and cause significant financial loss in China. The respiratory system and reproductive system are the main target systems.
Jun Zhao, Ling Zhu, Ling Zhu, Lei Xu, Fengqing Li, Huidan Deng, Yao Huang, Sirui Gu, Xianggang Sun, Yuancheng Zhou, Zhiwen Xu, Zhiwen Xu   +11 more
doaj   +1 more source