The identification and neurochemical characterization of central neurons that target parasympathetic preganglionic neurons involved in the regulation of choroidal blood flow in the rat eye using pseudorabies virus, immunolabeling and conventional pathway tracing methods [PDF]
The choroidal blood vessels of the eye provide the main vascular support to the outer retina. These blood vessels are under parasympathetic vasodilatory control via input from the pterygopalatine ganglion (PPG), which in turn receives its preganglionic ...
Anton Reiner +7 more
core +2 more sources
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal +5 more
wiley +1 more source
We report the case of a patient who presented with viral encephalitis and a pulmonary infection complicated with bilateral acute retinal necrosis after direct contact with diseased swine. Next-generation sequencing of the cerebrospinal fluid and vitreous
Yuwei Wang +5 more
doaj +1 more source
Pseudorabies virus exploits N6-methyladenosine modification to promote viral replication
IntroductionPseudorabies virus (PRV) is the pathogenic virus of porcine pseudorabies (PR), belonging to the Herpesviridae family. PRV has a wide range of hosts and in recent years has also been reported to infect humans.
Pei-Lun Yu +21 more
doaj +1 more source
Iowa Animal Industry News, 2012, Vol. 14, no. 1 [PDF]
Newsletter produced by Department of Agriculture and Land Stewardship about the animal industry in Iowa.Previously titled Animal Industry ...
core
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
An Overview of Live Attenuated Recombinant Pseudorabies Viruses for Use as Novel Vaccines
Pseudorabies virus (PRV) is a double-stranded, DNA-based swine virus with a genome approximating 150 kb in size. PRV has many nonessential genes which can be replaced with genes encoding heterologous antigens but without deleterious effects on virus ...
Bo Dong, Dante S. Zarlenga, Xiaofeng Ren
doaj +1 more source
Development Of Gene Deleted Recombinant Pseudorabies Virus [PDF]
The glycoprotein E (gE) and thymidine kinase (TK) genes are virulence-associated genes of pseudorabies virus (PrV). The study conducted was to shut down the gE gene from an established local TK defective (TK¯) PrV strain (TK¯gE+PrV).
Alauddin, Zeenathul Nazariah
core
The effects of viral load on pseudorabies virus gene expression [PDF]
Background Herpesvirus genes are classified into distinct kinetic groups on the basis of their expression dynamics during lytic growth of the virus in cultured cells at a high, typically 10 plaque-forming units/cell multiplicity of infection (
Judit S Tóth +3 more
core +2 more sources
Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley +1 more source

