Functional Disruption of a Chloroplast Pseudouridine Synthase Desensitizes Arabidopsis Plants to Phosphate Starvation [PDF]
Frontiers in Plant Science, 2017 Phosphate (Pi) deficiency is a common nutritional stress of plants in both agricultural and natural ecosystems. Plants respond to Pi starvation in the environment by triggering a suite of biochemical, physiological, and developmental changes that ...
Shan Lu +4 more
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iRNA-PseU: Identifying RNA pseudouridine sites
Molecular Therapy: Nucleic Acids, 2016 As the most abundant RNA modification, pseudouridine plays important roles in many biological processes. Occurring at the uridine site and catalyzed by pseudouridine synthase, the modification has been observed in nearly all kinds of RNA, including ...
Wei Chen +4 more
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Crystal Structure of Human Pus10, A Novel Pseudouridine Synthase
Journal of Molecular Biology, 2007 Pseudouridine (Psi) synthases catalyze the formation of one or more specific Psis in structured RNAs. Five families of Psi synthases have been characterized based on sequence homology. Pus10 has no significant sequence homology to these defined families and therefore represents a new family of Psi synthases.
Clare J, McCleverty +3 more
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Transfer RNA Modification Enzymes with a Thiouridine Synthetase, Methyltransferase and Pseudouridine Synthase (THUMP) Domain and the Nucleosides They Produce in tRNA [PDF]
Genes, 2023 Hiroyuki Hori
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Purification and crystallization ofEscherichia colipseudouridine synthase RluD
Acta Crystallographica Section D Biological Crystallography, 2003 RluD is the pseudouridine (Psi) synthase responsible for forming Psi1911, Psi1915 and Psi1917 in Escherichia coli 23S RNA. Out of the 11 Psi synthases in E. coli, only cells lacking RluD show a severe growth defect. In addition, RluD belongs to the RluA family of Psi synthases, one of the two remaining families without a representative crystal ...
Mark, Del Campo +2 more
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Genome-wide identification, characterization, and expression analysis unveil the roles of pseudouridine synthase (PUS) family proteins in rice development and stress response. [PDF]
Physiol Mol Biol Plants, 2023 Pseudouridylation, the conversion of uridine (U) to pseudouridine (Ѱ), is one of the most prevalent and evolutionary conserved RNA modifications, which is catalyzed by pseudouridine synthase (PUS) enzymes.
Dhingra Y +6 more
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The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface [PDF]
Nucleic Acids Research, 2021 Ute Kothe +2 more
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A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability [PDF]
EMBO Reports, 2017 Karine Choquet +2 more
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Loss of Drosophila pseudouridine synthase triggers apoptosis-induced proliferation and promotes cell-nonautonomous EMT. [PDF]
Cell Death Dis, 2015 Many developing tissues display regenerative capability that allows them to compensate cell loss and preserve tissue homeostasis. Because of their remarkable regenerative capability, Drosophila wing discs are extensively used for the study of ...
Vicidomini R +7 more
europepmc +2 more sources
Frontiers in Genetics, 2023 SHQ1 is an essential chaperone that binds the pseudouridine synthase dyskerin in the cytoplasm and escorts the enzyme to the nucleus, where dyskerin is assembled into small nucleolar RNPs (snoRNPs) of the H/ACA class.
Ismaël Alidou-D’Anjou +3 more
doaj +1 more source