Results 141 to 150 of about 2,361 (179)

The role and research progress of serine metabolism in tumor cells. [PDF]

Front Oncol
Lyu H, Bao S, Cai L, Wang M, Liu Y, Sun Y, Hu X.   +6 more
europepmc   +1 more source

De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma. [PDF]

Cancer Res
Teisseire M, Sahu U, Parola J, Tsai MC, Vial V, Durivault J, Grépin R, Cormerais Y, Molina C, Gouraud A, Pagès G, Ben-Sahra I, Giuliano S.   +12 more
europepmc   +1 more source

Epigenetic regulation of serine biosynthesis by PHF8 during neurogenesis. [PDF]

EMBO Rep
Artes MH, Iacobucci S, Barallobre MJ, Carballeira P, Garcia-Cajide M, Pérez-Venteo A, Padilla N, Viegas BS, Díaz-Vásquez A, Nacht AS, Vicent GP, Arbonés ML, de la Cruz X, Nieto M, Agell N, Mauvezin C, Martínez-Balbás MA.   +16 more
europepmc   +1 more source

One-carbon metabolism in cancer immunity: T-cell fitness, epigenetic programming, and therapeutic opportunities. [PDF]

Front Immunol
Wang R, Zhang N, Xu R, Xu Z, Li H.
europepmc   +1 more source

AD diagnosis model based on fusion of heterogeneous brain imaging and genomic data. [PDF]

Front Neurosci
Zhang Z, Zhang R, Yang W, Lv K, Wu M, Xu L.   +5 more
europepmc   +1 more source

Sustainable and innovative biological control strategies against <i>Pseudomonas syringae</i> pv<i>. tomato, Pseudomonas savastanoi</i> pv<i>. phaseolicola</i> and <i>Xanthomonas</i> spp. affecting vegetable crops: a review. [PDF]

Front Plant Sci
Giovanardi D, Biondi E, Biondo N, Quiroga N, Modica F, Puopolo G, Pérez Fuentealba S.   +6 more
europepmc   +1 more source

ABRO1 arrests cardiomyocyte proliferation and myocardial repair by suppressing PSPH

Molecular Therapy, 2023
The role of Abraxas 2 (ABRO1 or KIAA0157), a component of the lysine63-linked deubiquitinating system, in the cardiomyocyte proliferation and myocardial regeneration is unknown. Here, we found that ABRO1 regulates cardiomyocyte proliferation and cardiac regeneration in the postnatal heart by targeting METTL3-mediated m6A methylation of Psph mRNA.
Xin-Zhe Chen, Cui-Yun Liu
exaly   +3 more sources

PSPH promotes melanoma growth and metastasis by metabolic deregulation-mediated transcriptional activation of NR4A1

Oncogene, 2021
Metabolic deregulation, a hallmark of cancer, fuels cancer cell growth and metastasis. Here, we show that phosphoserine phosphatase (PSPH), an enzyme of the serine metabolism pathway, is upregulated in patient-derived melanoma samples. PSPH knockdown using short hairpin RNAs (shRNAs) blocks melanoma tumor growth and metastasis in both cell culture and ...
Romi Gupta, Xuchen Zhang, Eddy S Yang
exaly   +4 more sources

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Effect of PSPH on Angiogenesis and Migration of Hepatocellular Carcinoma Cells

2022 14th International Conference on Bioinformatics and Biomedical Technology, 2022
Fujian Wan
exaly   +3 more sources