Results 161 to 170 of about 2,435 (185)
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International Journal of Biological Macromolecules, 2023
T-2 toxin (T-2) with a molecular weight of 466.52 g/mol is an inevitable mycotoxin in food products and feeds, posing a significant threat to human and animal health. However, the underlying molecular mechanisms of the cytotoxic effects of T-2 exposure on porcine intestinal epithelial cells (IPEC-J2) remain unclear.
Wenbin Bao, Yin Zongjun, Zhengchang Wu
exaly +3 more sources
T-2 toxin (T-2) with a molecular weight of 466.52 g/mol is an inevitable mycotoxin in food products and feeds, posing a significant threat to human and animal health. However, the underlying molecular mechanisms of the cytotoxic effects of T-2 exposure on porcine intestinal epithelial cells (IPEC-J2) remain unclear.
Wenbin Bao, Yin Zongjun, Zhengchang Wu
exaly +3 more sources
Meta Gene, 2021
Abstract Male infertility (MI) is mainly caused by spermatogenic failure, and despite long years of assisted reproductive therapy, a significant number of cases remain idiopathic. Oligoasthenozoospermia (OA) is one of the most severe idiopathic MI forms, conditioned with decreased sperm motility and count.
Golnaz Shemshaki +3 more
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Abstract Male infertility (MI) is mainly caused by spermatogenic failure, and despite long years of assisted reproductive therapy, a significant number of cases remain idiopathic. Oligoasthenozoospermia (OA) is one of the most severe idiopathic MI forms, conditioned with decreased sperm motility and count.
Golnaz Shemshaki +3 more
openaire +1 more source
Cancer Gene Therapy
Hepatocellular carcinoma (HCC) progression is tightly linked to metabolic reprogramming and immune evasion. However, the transcriptional networks driving these processes remain misunderstood. Here, we identified a novel regulatory axis wherein the transcription factor SOX4 formed a stress-responsive complex with NRF2, as confirmed by co ...
Tien-An Lin, Yun-Shien Lee, Chi-Neu Tsai
exaly +3 more sources
Hepatocellular carcinoma (HCC) progression is tightly linked to metabolic reprogramming and immune evasion. However, the transcriptional networks driving these processes remain misunderstood. Here, we identified a novel regulatory axis wherein the transcription factor SOX4 formed a stress-responsive complex with NRF2, as confirmed by co ...
Tien-An Lin, Yun-Shien Lee, Chi-Neu Tsai
exaly +3 more sources
General Physiology and BiophysicsPhosphoserine phosphatase (PSPH), a key enzyme in the L-serine synthesis pathway, has been found to promote cancer progression through autophagy modulation. Here, we explored the functional role and molecular mechanisms of PSPH in colorectal cancer (CRC).
Bing Zhu
exaly +3 more sources
Cell Biology International, 2020
AbstractPhosphoserine phosphatase (PSPH), a key enzyme of the l‐serine synthesis pathway, has been involved in cancer progression and survival. However, limited evidence revealed the PSPH influence on hepatocellular carcinoma (HCC). Herein, we observed that PSPH expression was upregulated in both HCC tissues and cell lines, which was determined by ...
Jianli Zhang +3 more
openaire +2 more sources
AbstractPhosphoserine phosphatase (PSPH), a key enzyme of the l‐serine synthesis pathway, has been involved in cancer progression and survival. However, limited evidence revealed the PSPH influence on hepatocellular carcinoma (HCC). Herein, we observed that PSPH expression was upregulated in both HCC tissues and cell lines, which was determined by ...
Jianli Zhang +3 more
openaire +2 more sources
Cancer Research
Abstract Reprogrammed cellular metabolism is one of the key features of cancer and tumor microenvironment. L-3-phosphoserine phosphatase (PSPH) is one of the five rate-limiting enzymes in the biosynthesis of serine from glucose that supports cell proliferation. Here, we aim to study the role of PSPH in prostate cancer (PCa) and its tumor
Liankun Song +10 more
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Abstract Reprogrammed cellular metabolism is one of the key features of cancer and tumor microenvironment. L-3-phosphoserine phosphatase (PSPH) is one of the five rate-limiting enzymes in the biosynthesis of serine from glucose that supports cell proliferation. Here, we aim to study the role of PSPH in prostate cancer (PCa) and its tumor
Liankun Song +10 more
openaire +1 more source
Proceedings of the National Academy of Sciences, 2000
The hrp gene clusters of plant pathogenic bacteria control pathogenicity on their host plants and ability to elicit the hypersensitive reaction in resistant plants. Some hrp gene products constitute elements of the type III secretion system, by which
Justin Lee +11 more
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The hrp gene clusters of plant pathogenic bacteria control pathogenicity on their host plants and ability to elicit the hypersensitive reaction in resistant plants. Some hrp gene products constitute elements of the type III secretion system, by which
Justin Lee +11 more
openaire +1 more source
Phosphoserine phosphatase (
J B, Vincent +16 more
openaire +2 more sources