An investigation on the influence of pH and ionic strength on the adsorption and interfacial dilatational properties at the oil-water interface of pumpkin (Cucurbita pepo) seed protein hydrolysate [PDF]
Pumpkin (Cucurbita pepo) seed protein hydrolysate (PSPH) was obtained by enzymatic hydrolysis of pumpkin seed protein isolate using pepsin. Influence of pH (3, 5 and 8) and ionic strength, Ic (0–1 mol dm-3), on the adsorption kinetics of PSPH (diffusion ...
Bučko Sandra Đ. +6 more
doaj +4 more sources
Functional properties of pumpkin (Cucurbita pepo) seed protein isolate and hydrolysate [PDF]
Pumpkin seed protein isolate (PSPI) was enzymatically hydrolysed by pepsin to obtain pumpkin seed protein hydrolysate, PSPH. Investigation on solubility, interfacial and emulsifying properties of both PSPI and PSPH was conducted under different ...
Bučko Sandra Đ. +4 more
doaj +2 more sources
PSPH promotes the proliferation and metastasis of esophageal squamous cell carcinoma through MAPK signaling pathways. [PDF]
Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with limited therapeutic options and poor prognosis, underscoring the urgent need for novel molecular targets. Here, we identify phosphoserine phosphatase (PSPH) as a key oncogenic driver in ESCC.
Yongxin Zhao, Mingyue Tao
exaly +4 more sources
Exploring the DPP-IV Inhibitory, Antioxidant and Antibacterial Potential of Ovine “Scotta” Hydrolysates [PDF]
The aim of this work was to valorize the by-product derived from the ricotta cheese process (scotta). In this study, ovine scotta was concentrated by ultrafiltration and then subjected to enzymatic hydrolyses using proteases of both vegetable (4% E:S, 4 ...
Roberto Cabizza +7 more
doaj +2 more sources
Differential expression of enzymes associated with serine/glycine metabolism in different breast cancer subtypes. [PDF]
PURPOSE: Glycine and serine are well-known, classic metabolites of glycolysis. Here, we profiled the expression of enzymes associated with serine/glycine metabolism in different molecular subtypes of breast cancer and discuss their potential clinical ...
Sang Kyum Kim +2 more
doaj +4 more sources
Bacteriófagos en el control biológico de Pseudomonas syringae pv. phaseolicola agente causal del tizón de halo del frijol [PDF]
Pseudomonas syringae pv. phaseolicola (Psph) es el agente causal del tizón de halo del cultivo de frijol. El manejo de esta enfermedad está basado en antibióticos agrícolas o compuestos a base de cobre.
Evangelina Esmeralda Quiñones-Aguilar +3 more
doaj +2 more sources
The hrp gene clusters of plant pathogenic bacteria control pathogenicity on their host plants and ability to elicit the hypersensitive reaction in resistant plants. Some hrp gene products constitute elements of the type III secretion system, by which effector proteins are exported and delivered into plant cells. Here, we show that the hrpZ gene product
Lee, J. +11 more
openaire +4 more sources
PHGDH-Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration. [PDF]
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Xu HW +5 more
europepmc +2 more sources
Serine Ameliorates Cadmium-Induced Testicular Injury by Regulating the PGAM1/PHGDH Signaling Pathway. [PDF]
Serine mitigates cadmium‐induced testicular injury in mice by inhibiting the PGAM1/PHGDH pathway, restoring ion homeostasis and glycolysis, and relieving oxidative stress, inflammation, fibrosis, and apoptosis. ABSTRACT Cadmium (Cd) is a widespread environmental contaminant that impairs male reproductive function; however, the metabolic mechanisms ...
Wang X +8 more
europepmc +2 more sources
Background Because of dismal prognosis in gastric cancer, identifying relevant prognostic factors is necessary. Phosphoserine phosphatase (PSPH) exhibits different expression patterns in many cancers and has been reported to affect the prognosis of ...
Ma-Yan Huang +10 more
doaj +1 more source

