Results 201 to 210 of about 499,109 (301)
Abstract Background and aims Currently, there is no data‐driven cannabis reduction metric using biochemical verification, which represents a significant gap in cannabis harm reduction research, treatment and policy. Using aggregated data from 7 cannabis use disorder treatment trials, the aims of this analysis were to 1) determine if decreases in self ...
Erin A. McClure +6 more
wiley +1 more source
Varenicline for cannabis use disorder: A randomized controlled trial
Abstract Background and aims Although cannabis use is widespread and prevalence of cannabis use disorder (CUD) is increasing, limited advancements have been made in CUD medication development. The objective of this study was to test the efficacy of varenicline with medical management for reducing cannabis use in treatment‐seeking individuals with CUD ...
Aimee L. McRae‐Clark +8 more
wiley +1 more source
Computational Approach to Select Lead-Like Compounds From an Opioid Class of Novel Psychoactive Substances. [PDF]
Arsić B +4 more
europepmc +1 more source
Abstract Background and aims Ketamine assisted psychotherapy is a promising new treatment for alcohol use disorder (AUD). The psychoactive effects of repeated intravenous (IV) ketamine infusions in people with AUD and their mechanistic role in treating AUD are largely unknown.
Cassie Bloy +11 more
wiley +1 more source
To better understand why people use new psychoactive substances in prison - outcomes of polish, qualitative study. [PDF]
Wieczorek Ł, Dąbrowska K.
europepmc +1 more source
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer +16 more
wiley +1 more source
DAST-28 severity and injection-related harm risks among people using psychoactive substances in psychiatric and correctional settings in Mongolia: a multicenter cross-sectional study. [PDF]
Nyamdorj B +9 more
europepmc +1 more source
What anabolic–androgenic steroids reveal about the limits of current harm reduction models
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski +2 more
wiley +1 more source

