Results 181 to 190 of about 499,109 (301)

Effects of Obstructive Sleep Apnea on Personality and Temperament: A Cohort and Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is associated with neurocognitive impairment, but its causal relationship with personality traits remains poorly understood. This study investigates the association and causality between OSA and personality using both cohort and genetic data.
Jian‐Hong Liao, Yun‐Han Shi, Xin‐Peng Xu, Yan‐Ru Li, De‐Min Han   +4 more
wiley   +1 more source

Complementary insights from wastewater surveillance and the toxicology findings of clinical presentations involving new psychoactive substances in Australia. [PDF]

J Anal Toxicol
Bade R, Nadarajan D, Harris K, Harvey C, Jiranantakan T, Morgan H, Partridge E, Schumann J, Smith JL, Weber C, Hall W.   +10 more
europepmc   +1 more source

Impacts of Global Cannabis Policy Changes on Substance Use: A Systematic Review of Quasi‐Experimental Studies

The Milbank Quarterly, EarlyView.
Policy Points The liberalization of medical and recreational cannabis policies may increase cannabis initiation across age groups, with increased prevalence of cannabis use among young adults and adults and weaker effects among youth. Evidence also suggests increases in cannabis‐related health care utilization among adults.
SARAH B. WINDLE, PETER M. SOCHA, JASLEEN ARNEJA, SAM HARPER, GENEVIEVE GORE, GENEVIÉVE GARIÉPY, EVA GRAHAM, ANDREA BENEDETTI, ARIJIT NANDI   +8 more
wiley   +1 more source

Predicting affinity and potency of new psychoactive substances at cannabinoid 1 receptor with explainable artificial intelligence. [PDF]

Front Pharmacol
Schöning V, Alluisetti G, Grafinger KE, Pasin D, Stove CP, Gréen H, Weinmann W, Hammann F.   +7 more
europepmc   +1 more source

Lithium Use in Pregnancy and the Risk of Spontaneous Preterm Birth: An Australian Statewide Retrospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To investigate whether lithium exposure in pregnancy is associated with spontaneous preterm birth, congenital malformations and abnormal fetal growth. Design Statewide retrospective cohort study. Setting Victoria, Australia. Population 867 454 births (2009–2020), including 234 (0.03%) exposed to lithium during pregnancy.
Alexandra Roddy Mitchell, Anthea Lindquist, Richard J. Hiscock, Anna Forsythe, Hannah Gordon, Caroline S. E. Homer, Natasha Pritchard, Jessica Atkinson, Susan P. Walker, Stephen Tong, Roxanne Hastie   +10 more
wiley   +1 more source

Explainable Artificial Intelligence (xAI) for 5-HT_2A Receptor Binding Affinity of New Psychoactive Substances. [PDF]

Molecules
Schöning V, Grafinger KE, Pasin D, Stove CP, Weinmann W, Hammann F.   +5 more
europepmc   +1 more source

Prevalence of novel psychoactive substances in selected clinical urine specimens submitted for drug monitoring

Journal of Forensic Sciences, EarlyView.
Abstract Novel psychoactive substances (NPS) are compounds emerging as alternatives to more established drugs of abuse. They are constantly changing and being modified, which makes their detection difficult. The study objective was to determine the prevalence of NPS in selected clinical specimens. Deidentified urine specimen remnants were analyzed that
Jillian R. Neifeld, Theresa M. Meli, Sarah H. Bartock   +2 more
wiley   +1 more source

Protodesnitazene: The identification and tissue distribution of a new nitazene

Journal of Forensic Sciences, EarlyView.
Abstract Multiple new analogues from the 2‐benzyl benzimidazole or “nitazene” class of drugs have emerged on the drug market in recent years. Nitazenes are highly potent μ‐opioid receptor agonists that present a substantial public health concern due to their elevated risk of severe toxicity in overdose and their significant potential for misuse.
Andrew Griffiths, Nathan Milne, Michelle Johnston, Karen Blakey, Rogan Scott   +4 more
wiley   +1 more source

Ritual to relief: ethical frontiers in repurposing psychoactive substances. [PDF]

CNS Spectr
O'Leary E, Dodd S, Stahl S.
europepmc   +1 more source

The Local Spillover Effect of Marijuana Liberalization: Evidence From Material Misstatements

Accounting &Finance, EarlyView.
ABSTRACT This study documents an organizational spillover effect of marijuana liberalization on corporate financial reporting quality. Exploiting the staggered adoption of state‐level medical marijuana legalization (MML) laws, we find that firms headquartered in states adopting MMLs experience a higher likelihood of material misstatements.
Ting‐Chiao Huang, Jin Zhang
wiley   +1 more source