Results 171 to 180 of about 499,109 (301)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Mental disorders in adults with malnutrition: Prevalence and association with nutritional outcomes: A retrospective cohort study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Despite often coexisting, the association between mental disorders and malnutrition is not well characterized. This study aimed to describe the prevalence of mental disorders and their association with malnutrition, nutritional interventions, and clinical outcomes.
Vivian V. Nguyen, Paramat Thimichai, Jennifer Jin, Leanna Tsang, Patricia To, Leah Gramlich   +5 more
wiley   +1 more source

Coherence policy markers for psychoactive substances.

, 2014
Identifying effective approaches to creating coherent policies regarding licit and illicit drugs has been the priority of the Pompidou Group during its 2010-14 work programme.
Pike, Brigid, Muscat, Richard
core  

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

PM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy, Joshua C. Wiener, Karen Pratt, Laura Brunton   +3 more
wiley   +1 more source

Knowledge, attitudes, and perception toward new psychoactive substances among Saudi university students: a cross-sectional study. [PDF]

Front Psychiatry
Hamid AA, Alnijadi AA, Alrubaia L, Albraik L, Alfaifi M.   +4 more
europepmc   +1 more source

The association between red blood cell distribution width‐to‐albumin ratio and risk of insomnia: A cross‐sectional analysis of National Health and Nutrition Examination Survey and Chinese clinical data

Sleep Research, EarlyView.
Abstract Background The red blood cell distribution width‐to‐albumin ratio (RAR) is a novel composite biomarker of inflammation and nutritional status, yet its association with insomnia and underlying mechanisms remain poorly understood. Objective To investigate the association between the RAR and insomnia in two independent cohorts, comprising a ...
Jingying Ma, Jue Hu, Lei Zhang, Yilin Meng, Fa Ye, Hailun Xia, Hongmin Zhang, Yonghua Zhang   +7 more
wiley   +1 more source

In vivo evaluation of synthetic cannabinoid JWH-018 derivatives as potential new psychoactive substances. [PDF]

Sci Rep
Khan S, Baek M, Jang JH, Myeong IS.
europepmc   +1 more source

Beyond sleep‐specific bias: Eye‐tracking observations of general negative attentional biases linked to insomnia

Sleep Research, EarlyView.
Abstract Although attentional bias toward sleep‐related stimuli is well documented in insomnia and is regarded as a cognitive outcome arising after the disorder's onset, it remains unclear whether insomnia also involves a general negative attentional bias toward nonsleep negative stimuli, a transdiagnostic vulnerability for psychiatric disorders ...
Liping Hu, Ruolan Huang, Yuyin Wei, Jianhui Liang, Ruoqi Zhao, Yan Huang   +5 more
wiley   +1 more source

Amanita muscaria in the evolving novel psychoactive substances landscape - toxicological risks and clinical implications: a narrative review. [PDF]

Front Pharmacol
Ordak M.
europepmc   +1 more source