Results 21 to 30 of about 499,109 (301)

The Psychonauts’ Benzodiazepines; Quantitative Structure-Activity Relationship (QSAR) Analysis and Docking Prediction of Their Biological Activity

open access: yesPharmaceuticals, 2021
Designer benzodiazepines (DBZDs) represent a serious health concern and are increasingly reported in polydrug consumption-related fatalities. When new DBZDs are identified, very limited information is available on their pharmacodynamics.
Valeria Catalani   +6 more
doaj   +1 more source

A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases

open access: yesPharmaceuticals, 2022
Despite increasing reports, antidepressant (AD) misuse and dependence remain underestimated issues, possibly due to limited epidemiological and pharmacovigilance evidence.
Stefania Chiappini   +5 more
doaj   +1 more source

The use of psychoactive substances in Germany

open access: yesDeutsches Ärzteblatt international, 2022
Monitoring the use of psychoactive substances and substance-related problems in the population allows for the assessment of prevalence and associated health and social consequences.The data are derived from the Epidemiological Survey of Substance Abuse (ESA) 2021 (n = 9046, 18-64 years).
Christian, Rauschert   +5 more
openaire   +2 more sources

Screening Unknown Novel Psychoactive Substances Using GC-MS Based Machine Learning [PDF]

open access: yes, 2022
In recent years, there is a large increase in structural diversity of novel psychoactive substances (NPS), exacerbating drug abuse issues as these variants evade classical detection methods such as spectral library matching.
Swee Liang, Wong   +3 more
core   +1 more source

Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signalling [PDF]

open access: yes, 2015
Novel psychoactive substances are newly used designer drugs ("internet drugs", "research chemicals", "legal highs") potentially posing similar health risks to classic illicit substances. Chemically, many novel psychoactive substances can be classified as
Liechti, Matthias E., Matthias Liechti
core   +1 more source

Pharmacology of novel psychoactive substances [PDF]

open access: yes, 2016
This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core   +1 more source

Abuse of Prescription Drugs in the Context of Novel Psychoactive Substances (NPS): A Systematic Review

open access: yesBrain Sciences, 2018
Recently, a range of prescription and over-the-counter drugs have been reportedly used as Novel Psychoactive Substances (NPS), due to their potential for abuse resulting from their high dosage/idiosyncratic methods of self-administration.
Fabrizio Schifano   +3 more
doaj   +1 more source

Novel Psychoactive Substances and Behavioral Addictions [PDF]

open access: yesBioMed Research International, 2014
Copyright © 2014 Giovanni Martinotti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Giovanni Martinotti   +3 more
openaire   +7 more sources

Head shops and new psychoactive substances: a public health perspective.

open access: yes, 2023
In 2010, Ireland found itself at the eye of an international storm as a network of head shops emerged selling new psychoactive substances (NPS) and Irish youth rapidly became the heaviest users of NPS in Europe.
Smyth, Bobby P
core   +1 more source

Legal approaches to new psychoactive substances: first empirical findings.

open access: yes, 2023
BACKGROUND: Generic drug legislation, i.e., simultaneously banning groups of drugs, has been introduced worldwide to counteract the trade and use of emerging "new psychoactive substances" (NPSs) more effectively.
van Amsterdam, Jan   +2 more
core   +1 more source

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