Results 41 to 50 of about 499,109 (301)

Understanding the Opioid Epidemic through Pharmacovigilance Signals: an Analysis of Pharmacovigilance Datasets collecting Adverse Drug Reactions (ADRs) reported to EudraVigilance (EV) and the FDA Adverse Event Reporting System (FAERS) over 10 Years

Emerging Trends in Drugs, Addictions, and Health
Introduction: In the past twenty years, the consumption of opioid medications has reached significant proportions, leading to the so-called opioid epidemic, characterized by cyclical waves of heroin use and the non-medical use of pharmaceutical opioids ...
S. Chiappini, R. Vickers-Smith, A. Guirguis, J. Corkery, G. Martinotti, D.R. Harris, F. Schifano   +6 more
doaj   +1 more source

Benzodiazepine Boom: Tracking Etizolam, Pyrazolam, and Flubromazepam from Pre-UK Psychoactive Act 2016 to Present Using Analytical and Social Listening Techniques

Pharmacy
Introduction: The designer benzodiazepine (DBZD) market continues to expand whilst evading regulatory controls. The widespread adoption of social media by pro-drug use communities encourages positive discussions around DBZD use/misuse, driving demand ...
Anthony Mullin, Mark Scott, Giorgia Vaccaro, Giuseppe Floresta, Davide Arillotta, Valeria Catalani, John M. Corkery, Jacqueline L. Stair, Fabrizio Schifano, Amira Guirguis   +9 more
doaj   +1 more source

Development of a Quantum Dot-Based Immunochromatographic Assay for Rapid and Sensitive Detection of Non-Medical Etomidate Abuse

Biosensors
Etomidate is an ultrashort-acting imidazole-derived intravenous anesthetic. The non-medical abuse of etomidate as a new psychoactive substance has emerged as a critical public health challenge globally, particularly among adolescents, necessitating ...
Xin Yan, Liwei Jiang, Xiaolong Zhang, Yizhe Zhao, Zixin Wan, Jun Ma, Chunhui Song, Yikai Wang, Xingliang Liu   +8 more
doaj   +1 more source

Focus on Clozapine Withdrawal- and Misuse-Related Cases as Reported to the European Medicines Agency (EMA) Pharmacovigilance Database

Brain Sciences, 2020
Background: Clozapine is of high clinical relevance for the management of both treatment-resistant schizophrenia and psychotic disturbances with concurrent drug misuse.
Stefania Chiappini, Fabrizio Schifano, John Martin Corkery, Amira Guirguis   +3 more
doaj   +1 more source

The role of spirituality and religiosity in psychoactive substance use among adolescents in a Nigerian Hospital

Babcock University Medical Journal, 2022
Objective: Adolescence is a transition period where drug experimentation is common. Spirituality and religiosity have been recognized by literature as having a possible role in stabilizing good physical and mental health.
JOSHUA FALADE, Adekunle Fatai Mustapha, Adedayo Hakeem Oyebanji, Olusola Olawumi Falade   +3 more
doaj   +3 more sources

The Psychonauts’ World of Cognitive Enhancers

Frontiers in Psychiatry, 2020
BackgroundThere is growing availability of novel psychoactive substances (NPS), including cognitive enhancers (CEs) which can be used in the treatment of certain mental health disorders.
Flavia Napoletano, Flavia Napoletano, Fabrizio Schifano, John Martin Corkery, Amira Guirguis, Amira Guirguis, Davide Arillotta, Davide Arillotta, Caroline Zangani, Caroline Zangani, Alessandro Vento, Alessandro Vento, Alessandro Vento   +12 more
doaj   +1 more source

Is There a Risk for Semaglutide Misuse? Focus on the Food and Drug Administration’s FDA Adverse Events Reporting System (FAERS) Pharmacovigilance Dataset

Pharmaceuticals, 2023
Recent media reports commented about a possible issue of the misuse of antidiabetics related to molecules promoted as a weight-loss treatment in non-obese people.
Stefania Chiappini, Rachel Vickers-Smith, Daniel Harris, G. Duccio Papanti Pelletier, John Martin Corkery, Amira Guirguis, Giovanni Martinotti, Stefano L. Sensi, Fabrizio Schifano   +8 more
doaj   +1 more source

Substances psychoactives : consom

Cortica, 2023
Substances psychoactives : consomation, abus et dépendance
Joyce Oxenham, Giulia Suergiu
openaire   +1 more source

A Whole City Response to the Use of Novel Psychoactive Substances (NPS) by Young People in Newcastle-upon-Tyne [PDF]

, 2015
In recent years, Novel Psychoactive Substances (NPS) (otherwise known as ‘legal highs’) have posed an increasingly significant problem for practitioners and policy makers due to their widespread availability, largely unknown chemical composition and ...
Irving, Adele, Parker, Chris, Soppitt, Sarah   +2 more
core  

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source