Results 81 to 90 of about 3,223,608 (377)

Cannabis and psychosis : the Maltese contribution [PDF]

, 2010
Three different Maltese scientists have contributed to research on the link between cannabis and psychosis. The object of this article is to review and chronicle the work that has been done by these three colleagues in this field.
Agius, Mark, Grech, Anton, Zammit, Stanley   +2 more
core  

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Psychosis in Children: What is our present state of knowledge [PDF]

, 2005
Psychotic disorders are severe devastating illnesses that can seriously compromise the quality of life of many patients. Special considerations are needed for special patient populations such as, children and adolescents, as the developmental stage may ...
Sharma, I
core  

Cognitive alterations in patients with non-affective psychotic disorder and their unaffected siblings and parents [PDF]

, 2012
Meijer J, Simons CJP, Quee PJ, Verweij K, GROUP Investigators. Cognitive alterations in patients with non-affective psychotic disorder and their unaffected siblings and ...
Addington, Andreasen, Anselmetti, Appels, Bediou, Benton, Bilder, Blyler, Bora, Brand, Broome, Ceaser, Cornblatt, Dickinson, Egan, Egeland, Genetic Risk and Outcome in Psychosis (GROUP) Investigators, Glass, Green, Greenwood, Gur, Heinrichs, Heinrichs, Jabben, Keefe, Keefe, Keefe, Kelemen, Keshavan, Kremen, Kremen, Kéri, Meiran, Miller, Morice, Nolan, Nuechterlein, Palmer, Palmer, Pukrop, Savla, Sergi, Sitskoorn, Snitz, Sprong, Thornton, Van Hooren, Van Os, Van‘T Wout, Vauth, Versmissen, Wechsler, Welham, Yücel   +53 more
core   +2 more sources

Mental health-related stigma and pathways to care for people at risk of psychotic disorders or experiencing first-episode psychosis: a systematic review

Psychological Medicine, 2017
Background Stigma associated with mental illness can delay or prevent help-seeking and service contact. Stigma-related influences on pathways to care in the early stages of psychotic disorders have not been systematically examined.
P. Gronholm, G. Thornicroft, K. Laurens, Sara Evans-Lacko   +3 more
semanticscholar   +1 more source

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

Advanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li, Huiyang Huang, Cunhao Hu, Xuan Zhang, Song Lin, Xiaodan Huang, Ti‐fei Yuan, Kwok‐Fai So, Lu Huang, Chaoran Ren, Qian Tao   +10 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

A case report of adolescent lactation due to the drug blonanserin

BMC Psychiatry
Background Second-generation antipsychotic drugs are increasingly used to treat depressive disorders with psychotic symptoms. In addition to effectively managing psychotic symptoms, second-generation antipsychotics can also result in adverse drug ...
Peiyuan Tang, Chongze Wang, Wu Hong, Zhenghui Yi, Qinyu Lv   +4 more
doaj   +1 more source

Early clinical predictors and correlates of long-term morbidity in bipolar disorder [PDF]

, 2017
OBJECTIVES: Identifying factors predictive of long-term morbidity should improve clinical planning limiting disability and mortality associated with bipolar disorder (BD).
Baldessarini, R. J., DE CHIARA, Lavinia, Girardi, Paolo, Koukopoulos, A. E., Koukopoulos, Alexia, Reginaldi, D., Sani, Gabriele, Serra, Giulia, Tondo, L.   +8 more
core   +1 more source

Electroencephalographic delta/alpha frequency activity differentiates psychotic disorders: a study of schizophrenia, bipolar disorder and methamphetamine-induced psychotic disorder

Translational Psychiatry, 2018
Electroencephalography (EEG) has been proposed as a neurophysiological biomarker to delineate psychotic disorders. It is known that increased delta and decreased alpha, which are apparent in psychosis, are indicative of inappropriate arousal state, which
F. Howells, H. Temmingh, J. H. Hsieh, Andrea V van Dijen, D. Baldwin, Dan J Stein   +5 more
semanticscholar   +1 more source