Results 141 to 150 of about 22,716 (169)
Neferine inhibits vascular smooth muscle cell proliferation and migration in atherosclerosis by targeting CYS130 and PHE252 in PTEN. [PDF]
Front PharmacolJin Q +7 more
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The eIF5-mimic protein 5MP1: a regulator of translation stringency and a multifaceted oncogene. [PDF]
J BiochemBanerjee A +3 more
europepmc +1 more source
Exercise Stimulates <i>PINK-1, PARKIN, MFN-1</i>, and <i>ATG-3</i> Genes Expression Despite High-fat Diet: Tissue-specific Responses. [PDF]
In VivoDurak S +7 more
europepmc +1 more source
Regulation and Implementation of Apoptosis in Melanoma Tumor Cells with <i>BRAF</i>, <i>NRAS</i>, and <i>NF1</i> Gene Mutations. [PDF]
Curr Issues Mol BiolNosareva OL +9 more
europepmc +1 more source
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Brain Research, 2010
The identification of rare monogenic forms of Parkinson's disease (PD) has provided tremendous insights into the molecular pathogenesis of the disorder. Mitochondrial dysfunction and oxidative stress are thought to play a prominent role in the pathogenesis of PD, but how the monogenic mutation gene causes the disease onset or progression is largely ...
Jifeng Guo +2 more
exaly +3 more sources
The identification of rare monogenic forms of Parkinson's disease (PD) has provided tremendous insights into the molecular pathogenesis of the disorder. Mitochondrial dysfunction and oxidative stress are thought to play a prominent role in the pathogenesis of PD, but how the monogenic mutation gene causes the disease onset or progression is largely ...
Jifeng Guo +2 more
exaly +3 more sources
International Journal of Cardiology, 2018
Mitochondrial quality control is crucial to the development of angiotensin II (AngII)-induced cardiac hypertrophy. PTEN induced putative kinase 1 (PINK1) is rapidly degraded in normal mitochondria but accumulates in damaged mitochondria, triggering autophagy to protect cells. PINK1 mediates mitophagy in general, but whether PINK1 mediates AngII-induced
Yujia Bai, Qingchun Zeng, Hao Ren
exaly +3 more sources
Mitochondrial quality control is crucial to the development of angiotensin II (AngII)-induced cardiac hypertrophy. PTEN induced putative kinase 1 (PINK1) is rapidly degraded in normal mitochondria but accumulates in damaged mitochondria, triggering autophagy to protect cells. PINK1 mediates mitophagy in general, but whether PINK1 mediates AngII-induced
Yujia Bai, Qingchun Zeng, Hao Ren
exaly +3 more sources
Biochemical and Biophysical Research Communications, 2016
Chronic elevated glucose is harmful to pancreatic β-cells, resulting in pancreatic β-cells dysfunction and apoptosis. Understanding the molecular mechanisms associated with β-cells survival is pivotal for the prevention of β-cells injury caused by glucotoxicity.
Zhaohui Mo, Jingsong Zhou
exaly +3 more sources
Chronic elevated glucose is harmful to pancreatic β-cells, resulting in pancreatic β-cells dysfunction and apoptosis. Understanding the molecular mechanisms associated with β-cells survival is pivotal for the prevention of β-cells injury caused by glucotoxicity.
Zhaohui Mo, Jingsong Zhou
exaly +3 more sources
Biochemical and Biophysical Research Communications, 2015
Recent studies showed that increased mitochondrial fission is an early event of cell death during cerebral ischemia and dynamin-related protein 1 (Drp1) plays an important role in mitochondrial fission, which may be regulated by PTEN-induced putative kinase 1 (PINK1), a mitochondrial serine/threonine-protein kinase thought to protect cells from stress ...
Ding-I Yang +2 more
exaly +3 more sources
Recent studies showed that increased mitochondrial fission is an early event of cell death during cerebral ischemia and dynamin-related protein 1 (Drp1) plays an important role in mitochondrial fission, which may be regulated by PTEN-induced putative kinase 1 (PINK1), a mitochondrial serine/threonine-protein kinase thought to protect cells from stress ...
Ding-I Yang +2 more
exaly +3 more sources