Results 11 to 20 of about 8,420 (250)

Colour Confusion: Reviewing Ambiguities in the Identification and Classification of Chromatophore Deficiencies Among Amphibians. [PDF]

Ecol Evol
The colour of amphibian skin and eyes is the result of light interacting with multiple chromatophores (xanthophores, iridophores and melanophores), leading to challenges when trying to identify which of these cells are involved in colour abnormalities.
Gould J.
europepmc   +2 more sources

Pigments, Chromatophore Structure, and Gene Expression Underlying Colour Polytypy of a Panamanian Poison Frog. [PDF]

Mol Ecol
ABSTRACT Colour polytypism represents an example of phenotypic diversification shaped by genetic divergence and ecological pressures. Poison frogs of the genus Oophaga (Dendrobatidae) are highly polytypic in coloration, making them an ideal system for investigating the genetic and physiological basis of colour variation.
Mantzana-Oikonomaki V, Tamayo-Castillo G, Vásquez-Cháves V, Mora-Machado A, Zamora Ramirez WJ, Ibáñez R, Pröhl H, Rodríguez A.   +7 more
europepmc   +2 more sources

Analysis of the Influence of Changing and Fixed Temperatures on the Growth and Pteridine Content in the Head of Adults Sarcophaga crassipalpis (Diptera: Sarcophagidae)

Animals, 2023
Flesh flies (Diptera: Sarcophagidae) are regarded as significant in medical and veterinary entomology, and their development models can be utilized as considerable markers to ascertain the minimum postmortem interval (PMImin).
Fernand Jocelin Ngando, Xiangyan Zhang, Hongke Qu, Changquan Zhang, Fengqin Yang, Yakai Feng, Yanjie Shang, Sile Chen, Lipin Ren, Yadong Guo   +9 more
doaj   +1 more source

Highly Efficient Generation of Germline Mutations Using CRISPR/Cas9 in the Speckled Wood Butterfly <i>Pararge aegeria</i>. [PDF]

Ecol Evol
We demonstrate the efficient use of CRISPR/Cas9 to generate germline loss‐of‐function (LOF) mutations in the speckled wood butterfly (Pararge aegeria), an ecological model species. Targeting the yellow‐y gene, we achieved nearly 80% mosaic LOF phenotypes in adults and high germline mutation rates in offspring.
Shoshan AB, Tunström K, Wheat CW, Gotthard K.   +3 more
europepmc   +2 more sources

In silico and in vivo screening of triamterene synthetic analogues as promising diuretics

Medičnì Perspektivi, 2022
The modification of lead-compound aimed to the increasing of activity, decrement of toxicity or improvement of selectivity is one of the most important methods used for elaboration of novel medications.
K.V. Sokolova, V.V. Stavytskyi , O.Yu. Voskoboinik , O.A. Podpletnya , S.I. Kovalenko   +4 more
doaj   +1 more source

Novel Aminopyrimidine-2,4-diones, 2-Thiopyrimidine-4-ones, and 6-Arylpteridines as Dual-Target Inhibitors of BRD4/PLK1: Design, Synthesis, Cytotoxicity, and Computational Studies

Pharmaceuticals, 2023
Structural-based drug design and solvent-free synthesis were combined to obtain three novel series of 5-arylethylidene-aminopyrimidine-2,4-diones (4, 5a–c, 6a,b), 5-arylethylidene-amino-2-thiopyrimidine-4-ones (7,8), and 6-arylpteridines (9,10) as dual ...
Samar El-Kalyoubi, Samiha A. El-Sebaey, Sherin M. Elfeky, Hanan A. AL-Ghulikah, Mona S. El-Zoghbi   +4 more
doaj   +1 more source

Diversity oriented synthesis : substitution at C5 in unreactive pyrimidines by Claisen rearrangement and reactivity in nucleophilic substitution at C2 and C4 in pteridines and pyrido[2,3-d]pyrimidines [PDF]

, 2011
Diversity oriented synthesis of fused pyrimidines leads to scaffolds with many biological activities. In the case of the preparation of pyrido[2,3-d]pyrimidines from 2-alkylthiopyrimidines, the formation of a new carbon-carbon bond at C5 is required, a ...
Adcock, Jonathan Paul, Gibson, Colin, Huggan, Judith, Suckling, Colin   +3 more
core   +1 more source

Age-dependance of pteridines in the malaria vector, Anopheles stephensi

Pteridines, 2017
Determining the accurate age of malaria vectors is crucial to measure the risk of malaria transmission. A group of fluorescent chemicals derived from a pyrimidine-pyrazine ring structure known as pteridines from the head, thorax and whole body of adult ...
Edalat Hamideh, Akhoundi Mohammad, Basseri Hamidreza   +2 more
doaj   +1 more source

Studies and Comparison of Urinary Pteridine Patterns in Dogs and Cats and their Alteration in Various Neoplasias and Virus Infections

Pteridines, 1989
Urinary excretion levels of five pteridines in healthy cats and dogs and in 14 groups of animals with tumours or virus infections were determined by HPLC after partial purification by ion exchange chromatography.
Goldberg M., Gassner F., Merkenschlager M.   +2 more
doaj   +1 more source

Pteridines in the Assessment of Neoplasia [PDF]

cclm, 1982
Biological processes which might explain the association of pteridine excretion with proliferation are still unknown. Difficulties in the analysis and the determination of naturally occurring pteridines are described. The best quantitative estimations were achieved when measurement of non-reduced forms was attempted.
HAUSEN, A., Wachter, H.
openaire   +2 more sources