Results 11 to 20 of about 8,395 (249)
Eye can see clearly now: Identifying the locus associated with a white-eye mutation in honey bees (Apis mellifera). [PDF]
Insect Mol BiolWe performed a community science investigation with the beekeepers nationwide to find phenotypic mutants. Alongside a beekeeper in Kentucky, we performed a GWAS to identify a region associated with a white‐eye phenotype. We identified an eight bp region in a non‐coding RNA strongly associated with white eyes.
Shultz RR +5 more
europepmc +2 more sources
In silico and in vivo screening of triamterene synthetic analogues as promising diuretics
Medičnì Perspektivi, 2022 The modification of lead-compound aimed to the increasing of activity, decrement of toxicity or improvement of selectivity is one of the most important methods used for elaboration of novel medications.
K.V. Sokolova +4 more
doaj +1 more source
Oil Things Bright and Beautiful? How Hydrocarbon Pollution Impacts Guppy Ornamentation. [PDF]
Ecol EvolSpatial variation in crude oil pollution in Trinidad leads to differing levels of pollutant exposure in connected guppy populations. Male guppy ornamentation is an important sexually selected trait affected by environmental changes. Measuring area and intensity of this ornamentation, we found guppies from anthropogenically polluted habitats had greater
McGovern HR +3 more
europepmc +2 more sources
Diversity oriented synthesis : substitution at C5 in unreactive pyrimidines by Claisen rearrangement and reactivity in nucleophilic substitution at C2 and C4 in pteridines and pyrido[2,3-d]pyrimidines [PDF]
, 2011 Diversity oriented synthesis of fused pyrimidines leads to scaffolds with many biological activities. In the case of the preparation of pyrido[2,3-d]pyrimidines from 2-alkylthiopyrimidines, the formation of a new carbon-carbon bond at C5 is required, a ...
Adcock, Jonathan Paul +3 more
core +1 more source
Pteridines, 2017 Conjugated and unconjugated pteridines and their derivatives are important cofactors in cellular metabolism. Hence, the amount of unconjugated pteridines in biological fluids has been found to be modified as a result of several disorders. It is necessary
Espinosa-Mansilla Anunciación +1 more
doaj +1 more source
Age-dependance of pteridines in the malaria vector, Anopheles stephensi
Pteridines, 2017 Determining the accurate age of malaria vectors is crucial to measure the risk of malaria transmission. A group of fluorescent chemicals derived from a pyrimidine-pyrazine ring structure known as pteridines from the head, thorax and whole body of adult ...
Edalat Hamideh +2 more
doaj +1 more source
Pteridines, 1989 Urinary excretion levels of five pteridines in healthy cats and dogs and in 14 groups of animals with tumours or virus infections were determined by HPLC after partial purification by ion exchange chromatography.
Goldberg M. +2 more
doaj +1 more source
The role of urinary pteridines as disease biomarkers
Pteridines, 2017 Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Burton Casey, Ma Yinfa
doaj +1 more source
Allergology International, 2019 Background: Pteridines are metabolites of tetrahydrobiopterin, which serves as co-enzyme of nitric oxide synthase. We sought to investigate the usefulness of pteridines as biomarkers for childhood asthma control.
Saki Kasuga +10 more
doaj +1 more source
Pharmaceuticals, 2023 Structural-based drug design and solvent-free synthesis were combined to obtain three novel series of 5-arylethylidene-aminopyrimidine-2,4-diones (4, 5a–c, 6a,b), 5-arylethylidene-amino-2-thiopyrimidine-4-ones (7,8), and 6-arylpteridines (9,10) as dual ...
Samar El-Kalyoubi +4 more
doaj +1 more source