Results 61 to 70 of about 10,666 (255)
Frontiers in Microbiology, 2016 Tetrahydrofolate (THF) and its one-carbon derivatives, collectively termed folates, are essential cofact¬ors, but are inherently unstable. While it is clear that chemical oxidation can cleave folates or damage their pterin precursors, very little is ...
Jennifer eThiaville +9 more
doaj +1 more source
Studies on the relation between heme and nucleic acid syntheses in erythroid cell. 3. Nucleolus of erythroblast, changes in relation with cell specialization [PDF]
, 1969 The disappearance of nucleolus has been traced in the rat erythroid cells in relation with the cell specialization under varying conditions, i. e. in anemia with or without treatment by bromouracil and aminopterin.
Shigehisa, Morio
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In Vivo Biosynthesis and Direct Incorporation of Noncanonical Amino Acids into Proteins
ChemBioChem, Volume 26, Issue 22, November 17, 2025.This review evaluates engineered (semi)autonomous cell systems for the biosynthesis and incorporation of noncanonical amino acids (ncAAs) into proteins. While semi‐autonomous cells convert supplied precursors into ncAAs autonomous cells integrate biosynthetic pathways that produce these building blocks intracellularly.
Jan Hendrik Illies +2 more
wiley +1 more source
Synthetic Routes to a Library of Novel Methionine Synthase Inhibitors [PDF]
, 2020 Fungal infections are of continuous concern, especially with regard to immunocompromised patients. In an effort to develop new potential anti-fungal agents, we have begun synthesizing a library of potential inhibitors of the fungal Methionine Synthase ...
Bennett, Zachary +4 more
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Nanosecond photoreduction of inducible nitric oxide synthase by a Ru-diimine electron tunneling wire bound distant from the active site [PDF]
, 2009 A Ru-diimine wire, [(4,4′,5,5′-tetramethylbipyridine)_2Ru(F_9bp)]^(2+) (tmRu-F_9bp, where F_9bp is 4-methyl-4′-methylperfluorobiphenylbipyridine), binds tightly to the oxidase domain of inducible nitric oxide synthase (iNOSoxy). The binding of tmRu-F_9bp
Belliston-Bittner, Wendy +4 more
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Applications of QSPR and Machine Learning in Molecular Photonics
Advanced Optical Materials, Volume 13, Issue 33, November 25, 2025.Quantitative structureproperty relationships (QSPR) and machine learning (ML) are transforming photochemistry by enabling pre‐synthetic screening of photoactive molecules. This review outlines advances in data‐driven discovery of optical materials and functional dyes, identifies effective descriptors and models for photophysical processes, and provides
Andrey A. Buglak +2 more
wiley +1 more source
Advanced Science, Volume 12, Issue 42, November 13, 2025.This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian +15 more
wiley +1 more source
Modulation of Free Radical Formation by Pterin Derivatives
Pteridines, 2004 All classes of pterins, fully reduced tetrahydropterins, aromatic pterins and dihydropterins have been investigated upon their effects on radical mediated reactions.
Karl Oettl +2 more
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The pterin molybdenum cofactors.
Journal of Biological Chemistry, 1992 crassa, demonstrated that the inactive apoprotein of nitrate reductase in extracts of the mutant could be reconstituted by the addition of denatured preparations of purified molybdoenzymes from animal, fungal, or bacterial origin. This crucial finding showed that mol- ybdoenzymes contain a dissociable entity fitting the description of a cofactor and ...
K V, Rajagopalan, J L, Johnson
openaire +2 more sources
First Synthesis of Asperopterin A, an Isoxanthopterin Glycoside from Aspergillus Oryzae [PDF]
, 2013 The key precursor, N-2-(N,N -dimethylaminomethylene)-6-hydroxymethyl-8-methyl-3-[2-(4-nitrophenyl)ethyl]-7-xanthopterin (16) was efficiently prepared from 2,5-diamino-6-methylamino-3H-pyrimidin-4-one (5) and ethyl 3-(tert-butyldimethylsilyloxy)-2 ...
Hanaya, Tadashi, Yamamoto, Hiroshi
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