Results 81 to 90 of about 9,467 (211)

Inactivation of tyrosinase photoinduced by pterin

Biochemical and Biophysical Research Communications, 2012
Tyrosinase catalyzes in mammals the first and rate-limiting step in the biosynthesis of the melanin, the main pigment of the skin. Pterins, heterocyclic compounds able to photoinduce oxidation of DNA and its components, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder in which the protection against UV ...
Dantola, Maria Laura, Gojanovich, Aldana Daniela, Thomas, Andrés Héctor   +2 more
openaire   +3 more sources

Metabolic Processes Preserved as Biosignatures in Iron-Oxidizing Microorganisms: Implications for Biosignature Detection on Mars [PDF]

Iron-oxidizing bacteria occupy a distinct environmental niche. These chemolithoautotrophic organisms require very little oxygen (when neutrophilic) or outcompete oxygen for access to Fe(II) (when acidophilic).
Emerson, David, Floyd, Melissa A. Merrill, Grubisic, Andrej, Williams, Amy J.   +3 more
core   +1 more source

Tetrahydrobiopterin Deficiency: From Phenotype to Genotype [PDF]

, 2017
As a result of the selective screening worldwide during the last 18 years, approximately 250 patients with tetrahydrobiopterin deficiency were discovered.
Blau, Nenad, Dhondt, Jean-Louis, Heizmann, Claus W., Thöny, Beat   +3 more
core  

7-Carboxy-7-deazaguanine Synthase: A Radical [PDF]

, 2017
Radical S-adenosyl-L-methionine (SAM) enzymes are widely distributed and catalyze diverse reactions. SAM binds to the unique iron atom of a site-differentiated [4Fe-4S] cluster and is reductively cleaved to generate a 5'-deoxyadenosyl radical, which ...
Bandarian, Vahe, Bruender, Nathan A., Dowling, Daniel P., Drennan, Catherine L, Grell, Tsehai Ariane, McCarty, Reid M.   +5 more
core   +1 more source

A call to integrate non‐visual functions of pigments and their interactions with visual functions to understand global change impacts on visual systems

Functional Ecology, Volume 39, Issue 10, Page 2588-2600, October 2025.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Animal coloration serves a variety of visually related functions in nature (e.g. mate choice, aposematism and camouflage) but the pigments in integumentary tissues such as skin, scales and feathers may also serve functions unrelated to the visual environment (e.g ...
Beth A. Reinke, Julian D. Avery, Jessica Hua   +2 more
wiley   +1 more source

Biosynthesis of Pteridines in Insects: A Review

Insects
Pteridines are important cofactors for many biological functions of all living organisms, and they were first discovered as pigments of insects, mainly in butterfly wings and the eye and body colors of insects. Most of the information on their structures
Juan Ferré
doaj   +1 more source

Crystal structure of (2-amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(1,10-phenanthroline-κ2N,N′)zinc trihydrate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, [Zn(C8H5N5O3)(C12H8N2)(H2O)]·3H2O, a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate ligand, a bidentate ancillary 1,10-phenanthroline (phen) ligand and a water molecule complete a distorted octahedral coordination ...
Siddhartha S. Baisya, Baidyanath Ghosh, Parag S. Roy   +2 more
doaj   +1 more source

Increasing Tetrahydrobiopterin in Cardiomyocytes Adversely Affects Cardiac Redox State and Mitochondrial Function Independently of Changes in NO Production [PDF]

, 2016
Tetrahydrobiopterin (BH4) represents a potential strategy for the treatment of cardiac remodeling, fibrosis and/or diastolic dysfunction. The effects of oral treatment with BH4 (Sapropterin™ or Kuvan™) are however dose-limiting with high dose negating ...
Bennett, Brian, Ionova, Irina A., Pieper, Galen M., Sethumadhavan, Savitha, Vasquez-Vivar, Jeannette, Whitsett, Jennifer   +5 more
core   +1 more source

Fundamental Molecules of Life are Pigments which Arose and Evolved to Dissipate the Solar Spectrum

, 2014
The driving force behind the origin and evolution of life has been the thermodynamic imperative of increasing the entropy production of the biosphere through increasing the global solar photon dissipation rate.
Michaelian, Karo, Simeonov, Aleksandar
core   +2 more sources

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation. [PDF]

, 2015
Activation of the NLRP3 inflammasome by microbial ligands or tissue damage requires intracellular generation of reactive oxygen species (ROS). We present evidence that macrophage secretion of IL1β upon stimulation with ATP, crystals or LPS is mediated by
Busso, N., Ives, A., LeRoy, D., Martinon, F., Miner, J.N., Nomura, J., Roger, T., Simon, G., So, A.   +8 more
core   +1 more source