A model to understand type I oxidations of biomolecules photosensitized by pterins
Journal of Photochemistry and Photobiology, 2021 Photosensitized oxidations, in part responsible for the harmful effect of UV and visible radiation on biological systems, can take place through type I (generation of radicals) and type II (singlet oxygen) mechanisms.
Carolina Lorente +2 more
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Comparative metabolism of conjugated and unconjugated pterins in Crithidia, Leishmania and African trypanosomes. [PDF]
PLoS Neglected Tropical DiseasesMammalian cells synthesise tetrahydrobiopterin de novo, an essential cofactor for hydroxylation of aromatic amino acids, cleavage of ether lipids and the synthesis of nitric oxide.
Han B Ong, Susan Wyllie, Alan H Fairlamb
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Two Cases of 6-Pyruvoyl Tetrahydropterin Synthase Deficiency: Case Report and Literature Review [PDF]
Children, 2023 6-pyruvoyl tetrahydropterin synthase deficiency (PTPSD) is a rare neurometabolic disease that can be diagnosed in newborn screening (NBS) and is part of the family of tetrahydrobiopterin deficiency disorders (BH4Ds). It is essential to diagnose and treat
Lucia Maria Sur +4 more
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Synthesis, Redox and Spectroscopic Properties of Pterin of Molybdenum Cofactors [PDF]
Molecules, 2022 Pterins are bicyclic heterocycles that are found widely across Nature and are involved in a variety of biological functions. Notably, pterins are found at the core of molybdenum cofactor (Moco) containing enzymes in the molybdopterin (MPT) ligand that ...
Kyle J. Colston, Partha Basu
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Pushing at the Boundaries of Pterin Chemistry [PDF]
MoleculesPterins are molecules of substantial interest as they occur in nature in a number of forms with quite distinct and often indispensable roles. Chemically, the synthesis of the principle pterin scaffold is comparably simple, while the insolubility of the ...
Jevy V. Correia +2 more
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Cerebrospinal Fluid Neurotransmitters, Pterins, Folates and Amino Acids in Paediatric Onset Epilepsies: A Tertiary Centre Retrospective Cohort Study [PDF]
ChildrenObjectives: To investigate the clinical value of cerebrospinal fluid (CSF) testing for biogenic amine, pterins, amino acids, and folates in paediatric onset epilepsies. Methods: Retrospective clinical and biochemical phenotyping of patients with epilepsy
Mario Mastrangelo +6 more
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Autoxidation Kinetics of Tetrahydrobiopterin—Giving Quinonoid Dihydrobiopterin the Consideration It Deserves [PDF]
Molecules, 2023 In humans, tetrahydrobiopterin (H4Bip) is the cofactor of several essential hydroxylation reactions which dysfunction cause very serious diseases at any age.
Ayoub Boulghobra +7 more
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Pterin-Based Red Coloration Predicts the Outcome of Male–Male Competition in Guinan Toad-Headed Lizard [PDF]
AnimalsAnimal coloration offers a unique opportunity to explore the evolutionary mechanisms underlying phenotypic diversity. Conspicuous coloration caused by pigments plays a crucial role in social signaling across multiple species by conveying information ...
Xiao Xiao +8 more
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Pterin function in bacteria [PDF]
Pteridines, 2017 Pterins are widely conserved biomolecules that play essential roles in diverse organisms. First described as enzymatic cofactors in eukaryotic systems, bacterial pterins were discovered in cyanobacteria soon after.
Feirer Nathan, Fuqua Clay
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Cells, 2019 Inborn errors of monoamine neurotransmitter biosynthesis and degradation belong to the rare inborn errors of metabolism. They are caused by monogenic variants in the genes encoding the proteins involved in (1) neurotransmitter biosynthesis (like tyrosine
Oya Kuseyri Hübschmann
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